-
Blood: In multiple myeloma, monoclonal immunoglobulin promotes bone loss
Time of Update: 2020-07-12
Most patients with multiple myeloma develop severe bone-soluble diseases Myeloma cells secrete immune globulin, the presence of monoclonal immunoglobulin in the serum of patients is important dia
-
Brukinsa, a BTK inhibitor in Baiji Shenzhou, is under review in Europe for the treatment of Fahrenheit polycyloproteinemia
Time of Update: 2020-07-12
Brukinsa (zanubrutinib, Zebtinib), a BTK small molecule inhibitor developed by Baiji Shenzhou, has been censored by European regulators to treat patients with Fahrenheit polycyteproteinemia (WM)
-
59-year-old patient without cancer markers for more than 3 years after receiving CAR-T cell immunotherapy
Time of Update: 2020-06-25
Even after three years, Andrew Parker and his oncologist, Michael Bishop, m.D., at the University of Chicago Medical Center, are in awe of the amazing turn of CAR-T cell immunotherapy 2016, Parker
-
Gene therapy LentiGlobin Treatment of Sickle Cell Disease: Phase I / Phase II Clinical Positive Results
Time of Update: 2020-06-25
The latest data from Bluebird Bio's ongoing phase I/II study of gene therapy LentiGlobin for the treatment of sickle cell disease (SCD) shows that severe vascular aocstatory crisis (VOC) and acute
-
Baiji Shenzhou announced that combination chemotherapy was used in non-squamous non-small cell lung cancer patients, the stage 3 trial reached the main end point of progression-free survival
Time of Update: 2020-06-25
Baiji Shenzhou announced that its anti-PD-1 monoanti-relizumab combined permeitus and platinum chemotherapy, a phase 3 trial for first-line treatment of non-squamous non-small cell lung cancer (NSCL
-
Concerned about the rare disease "Red Blood Cell-producing Prosofe and X-Chain Dystrophy": Launched Global Phase III Clinical Trials of MT-7117
Time of Update: 2020-06-25
Mitsubishi Tianbian Pharmaceutical Co., Ltd announced today that it has begun a global Phase III clinical trial of MT-7117, a selective black skin quality 1 receptor (MC1R) agonisant, aimed at treat
-
FDA Awards FT-4202 Orphan Drug for Sickle Cell Disease
Time of Update: 2020-06-25
FORMA, a clinically phased biopharmaceutical company focused on rare haematology diseases and cancers, recently announced that the FDA has awarded its FT-4202 orphan drug designation, which is curre
-
Collection: Collection of Blood Research Highlights, April 16, 2020
Time of Update: 2020-06-25
The volume of high-start total metabolic tumors helps identify ultra-high-risk DLBCL populations https://doi.org/10.1182/blood.2019003526 https://doi.org/10.1182/blood.2019003526 early identif
-
PKR activator mitapivat treatment of thalassemia: continued improvement in patient hemoglobin levels
Time of Update: 2020-06-25
Agios Pharmaceuticals recently reported on Phase II studies showing that its experimental oral drug mitapivat (PKR activator) significantly improved hemoglobin (Hb) levels and the associated markers
-
NMPA approves anti-PD-1 monoanti-relylibeads in Baiji Shenzhou for the treatment of locallate or metastatic urethral skin cancer
Time of Update: 2020-06-25
Baiji Shenzhou announced that its anti-PD-1 antibody tislelizumab (tislelizumab) has been approved by the State Drug Administration of China (NMPA) for pD-L1 high expression, during or after platinu
-
Blood: The best drug for isosome platelet hyperplasia, aspirin optimizes antiplatelet therapy
Time of Update: 2020-06-25
Ispeciallyanocal hyperplasia (ET) is characterized by abnormal macrocytocell production and an increased risk of blood clots Recommended antithrombotic treatment options: small dose aspirin, once da
-
A selection of Lancet research highlights on April 18, 2020
Time of Update: 2020-06-25
1 Gixithabin-Platinum Chemotherapy for the late-stage epithelial skin cancer DOI: https://doi.org/10.1016/S0146/S0146-6736 (20)30415-3 is rare and pre-conditioned than bladder ontheuliopath
-
Blood: Vascular autonomic nerve function abnormalities in sickle cell disease (SCD)
Time of Update: 2020-06-25
Subjects of sickle cell disease (SCD) exhibited subjective hypersensitivity to cold and hot sensations in the experimental environment, such as cold exposure and other known causes that cause the p
-
Lancet: Acalabrutinib's first-line treatment of chronic lymphocytic leukemia is effective
Time of Update: 2020-06-25
Acalabrutinib is an alternative Bruton tyrosine kinase inhibitor that has the activity to treat chronic lymphocytic leukemia The researchers looked at the efficacy of Acalabrutinib in the treatment
-
AACR 2020: Ibtinib and Litoxi monotherapy follicle lymphoma Phase III Research Launch (PERSPECTIVE Study)
Time of Update: 2020-06-24
research background For elderly or patients with fissyllosic lymphoma (FL), the first-line chemo-free (no chemotherapy) treatment options are very limited At present, rituximatomaishasis has been
-
Cell Metab: Lactic acid regulates muscle ischemia
Time of Update: 2020-06-24
Endothelial cells (EC) produce signals that help organs regenerate, but there have been reports of metabolic communication within blood vessels recently, researchers found that EC-specific glycoen
-
Bcl-2 inhibitor APG-2575 for use in chronic lymphocytic leukemia or small lymphocytic lymphoma in Phase Ib/II clinical, approved by NMPA
Time of Update: 2020-06-24
Ascentage Pharma announced that it has received approval from the State Drug Administration of China (NMPA) for its Ib/II phase of its new Bcl-2 selective inhibitor APG-2575 to treat recurrent/refra
-
Blood: Effects of arginine therapy on mitochondrial function during vascular closed pain in sickle cell disease in children
Time of Update: 2020-06-24
The mitochondrial function of sickle cell disease (SCD) changes, in part because of the low bioavailability of nitric oxide (NO) Arginine is the substrate that produces NO and becomes severely defic
-
Virol J: Non-transplantative acute leukemia patients receiving chemotherapy combined with human herpes virus
Time of Update: 2020-06-24
The human herpes virus (HHVs) still has an incubation period after primary infection and can be reactivated after immunosuppression and chemotherapy Little is known about its incidence, potential re
-
Blood: Three aspirin treatment options in optimizing isoplate hyperpluse patients with antiplatelet treatment comparison
Time of Update: 2020-06-24
Ispeciallyanocal hyperplasia (ET) is characterized by abnormal macrocytocell production and an increased risk of blood clots Daily small-dose (od) aspirin is the recommended antithrombotic treatment