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NAT COMMUN: Mitochondria control angiogenesis during wound healing and tumor growth.
Time of Update: 2020-07-28
Vascular is a highly malleable tissue that can switch from a stationary state to an active proliferative state during angiogenesis In this process, metabolic reprogramming of endothelial cells () is e
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JAMA Surg: FOLFIRINOX or GA first-line treatment of limited pancreatic catheter adenocarcinoma.
Time of Update: 2020-07-28
Fluorouresy, calcium zolinalate, Ilitikon, Oshariplatin and Gixithabin combined with yewol are the first-line chemotherapy programs for pancreatic cancer Recently, researchers compared or first-line t
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Acta Neuropathologica: A case of COVID-19 in young people H3K27M mutant diffuse midline glial accompanied by a wide range of intracancerary microthrombosis.
Time of Update: 2020-07-28
Little is known about the effects of new coronavirus diseases on tumor biology associated with high coagulation and cerebrovascular accidents Malignant tumors are closely related to high coagulation s
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NEJM Cases . . . The feces is a silver metastatic colorectal cancer.
Time of Update: 2020-07-28
human feces are usually light brown to dark brown, which is produced by a combination of bile from dead red blood cells and bilirubin derivatives of urobilin.
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Repeated black stool for 1 year but can not find the source of bleeding? Notice that the disease will disguise.
Time of Update: 2020-07-28
Table 2: gist classification in Chinese expert consensus on diagnosis and treatment of gastrointestinal stromal tumors (2017 Edition) the prognosis of gist is closely related to tumor size and depth of invasion, mitotic index and metastasis.
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New discovery of breast cancer! Identify 32 new susceptibility gene constellations.
Time of Update: 2020-07-28
Today, I'd like to share with you an article published in Nature Genetics (if: 25.455) in June: genome wide association study identities 32 new breast cancer susceptibility loci from overall and subtype specific We conducted a genome-wide association study using standard and new methods to explain potential tumor heterogeneity based on the status and tumor grade of estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2, and identified 32 new susceptibility loci.
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PNAS: Northwestern University: Nanoparticle therapy can significantly increase survival in breast cancer patients and prevent breast cancer recurrence.
Time of Update: 2020-07-28
Introduction: Breast cancer is often referred to as the "pink killer" and its incidence rate ranks first among women with malignant tumors The incidence of breast cancer in China is on the rise year b
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In patients with follicular lymphoma, you need to know, don't miss it.
Time of Update: 2020-07-28
Follicular lymphoma (FL) is one of the most common B-cell lymphoma in non Hodgkin's lymphoma except diffuse large B-cell lymphoma. It is also a subtype of lymphoma with high cure rate after drug treat
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Today's "King Blast" combination is the star of the joint therapy.
Time of Update: 2020-07-28
▍ endometrial cancer in September 2019, based on the results of a single arm phase II keynote-146 / study 111 clinical trial, the combination of "Wang Bao" was approved by FDA for the treatment of patients with advanced endometrial cancer who did not have high microsatellite instability (MSI-H) or mismatch repair defect (dmmr) after systemic treatment.
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Minimally invasive surgery is not the best treatment strategy for some gynaecological cancers.
Time of Update: 2020-07-28
in a systematic review and meta-analysis, the researchers identified 15 observational studies (9499 patients) on the treatment of early cervical cancer with a median follow-up time of more than 2 years.
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CSCO guidelines are released
Time of Update: 2020-07-28
"The annual progress seminar on clinical oncology in China, sponsored by the Chinese Society of Clinical Oncology() was held on the line recently, and experts and scholars summarized the update of th
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A number of new drugs are expected to be available in China; ESMO colon cancer guidelines are released; and new targeted drugs are released with new data. Tumor intelligence.
Time of Update: 2020-07-28
Every day 1 minute, give you the professional "talk material" in tumor circle! (if you need the original literature, you can get it through the wechat YXJ Oncology) Jie said that as a professional in
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Domestic anti-PD-1 therapy! Jiahe biogeptanolimab listing application by the State Drug Administration to treat peripheral T-cell lymphoma (PTCL)
Time of Update: 2020-07-28
Jiahe Biopharmaceuticals ( ) is a biopharmaceutical company focused on the development and commercialization of innovative and quasi-commercialized oncology and immunodeficiency therapies Recently, th
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Several articles focus on new advances in the field of lung adenocarcinoma!
Time of Update: 2020-07-28
"Lung adenocarcinoma is a kind of non-small cell lung cancer which is more likely to occur metastasis In recent years, the incidence of lung adenocarcinoma in the population has continued to rise In
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Mol Cancer: The Shanghai Nine-Yuan Fan Group team discovered a new type of LncRNA that accelerates the onset of retinoblastoma and reveals its specific molecular mechanisms.
Time of Update: 2020-07-28
previously, fan xianqun's team found that lncrna gau1 can recruit transcription elongation factor a1 (tcea1) to the promoter of peptide N-acetylgalactosamine transferase 8 (galnt8), thus up regulating the expression of oncogene and accelerating the tumorigenesis of retinoblastoma.
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Science sub-journal! Cancer cells rely on the original energy generation pathway to multiply and spread.
Time of Update: 2020-07-28
NEW YEAR (UPI) -- In order to speed up their rapid proliferation of tumor cells rely on glycoenzyme, which is a primitive metabolic pathway cancer can easily use to get energy to grow and spread Glysi
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More uncertainty about BRCA-related platinum chemotherapy for breast cancer.
Time of Update: 2020-07-28
however, geparsixto test (NEJM JW Oncol Hematol SEP 2014 and lancet Oncol 2014 Jun; 15:747 and NEJM JW Oncol Hematol SEP 2017 and JAMA Oncol 2017; 3: 1378) showed that the addition of platinum drugs (carboplatin) to neoadjuvant therapy of paclitaxel, anthracycline and antiangiogenic agent (bevacizumab) did not significantly improve the pathological complete response rate (PCR) in patients with HER2 + or BRCA associated TNBC disease.
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Acta Neuropathologica: Spatial enrichment of glioblastoma cell state.
Time of Update: 2020-07-28
The authors determine whether the cell state may correspond to the terrain location within the tumor The gene expression spectrum of cell state and proliferation was extracted from the study and appl
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7 plus multi-group prediction of drug sensitivity lncRNA.
Time of Update: 2020-07-28
this paper mainly focuses on the use of bioinformatics methods to identify lncrnas associated with drug response in breast cancer by integrating multi-dimensional genomic data.
the researchers identified lncrnas (drlncs) associated with drug response by combining lncrna, microRNA, mRNA, methylation levels, somatic mutations, and survival data of cancer patients receiving drug treatment.
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Multiple articles focus on new results in cancer heterogeneity research!
Time of Update: 2020-07-28
"Cancer heterogeneity is one of the characteristics of malignant tumor, which refers to the tumor in the growth process after many times the division and proliferation of its subcells show molecular biology or genetic changes so that the growth rate of the tumor, invasive ability, sensitivity to drugs, prognosis and other aspects of difference In this paper, a number of important research results to read together scientists in the cancer heterogeneity research to share with you!
