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Palbociclib is not effective for adult patients with recurrent glioblastoma
Time of Update: 2020-06-03
Jennie W Taylor of neurosurgery at the University of California, San Francisco, USA, has conducted research on the efficacy of recurrent GBM and its pharmacokineticand and pharmacodynamics characteris
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The role of PROX1 in the occurrence and development of glioblastoma
Time of Update: 2020-06-03
Ref: Goudarzi KM , et al Cancer Res 2018 Oct 15;78 (20):5901-5916 doi: 10.1158/0008-5472.CAN-18-0320 Epub 2018 Aug 22.: has studied that the homologous domain transcription factor PROX1 is associate
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Deep learning to find prognostic-related genes in GBM patients
Time of Update: 2020-06-03
The deep learning survival prediction model explores genes closely related to GBM stem cells and tolerable genes that can be used to guide patient synods Compared with the traditional Cox proportional
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Lomoxine combined with tamoxamine improves the efficacy of GBM
Time of Update: 2020-06-03
The German Society of Oncology's Neuro-Oncology Working Group initiated a randomized open label phase 3 CeTeG/NOA-09 clinical trial to further analyze the application value of lomostine and tamoxifen
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Building a model of glioblastoma organs
Time of Update: 2020-06-03
There was no statistical difference in the rate of growth of GBM in the brains of young and older organ brains However, gbM growth patterns varied in the brains of organs of different ages, and glioma
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Tyrosine-PET identifies GBM "recurrence" or "late false progression"
Time of Update: 2020-06-03
Diagnosing "false progression" of glioblastoma (GBM) is a difficult problem; Studies have shown that false progression may be caused by changes in the blood-brain barrier caused by radiation and chemo
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Prospects for the application of clinical sequencing of adult glioma
Time of Update: 2020-06-03
Siyuan Zheng of the Neurotumor Department at the University of Texas Anderson Cancer Center used the T200 gene panel of the Anderson Cancer Center to conduct a forward-looking cohort study of 237 glio
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Characteristic table of NFPA prolactin elevated patients
Time of Update: 2020-06-03
Ref: Park SS, et al World Neurosurg 2018 Nov;119:e1035-e1040 doi: 10.1016/j.wneu.2018.08.068 Epub 2018 Aug 23.: developed hyperlactinemia in patients with non-functional pituitary adenomas (nonfunct
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Mass spectrometry detection 2-HG to quickly diagnose IDH mutations
Time of Update: 2020-06-03
Traditional PCR sequencing and immunohistomydization require more than 1 day to get the test results, which is not suitable for rapid diagnosis Therefore, on the basis of previous discoveries, the aut
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Four molecular markers of glioma
Time of Update: 2020-06-03
The initial IDH mutation was closely related to the formation of low-level glioma, followed by 1p/19q co-miss, TERT mutation or P53 and ATRX mutation; - From the article chapter (Ruff: Ruff: Ruff: R
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Evaluation of craniofacial endoscopic surgery
Time of Update: 2020-06-03
Low-level olfactory neuroblastoma is preferred by ESBS, but high-level olfactory neuroblastoma usually requires open-cranial surgery There is little data on cartilage sarcoma, but early results show t
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Analysis of the molecular spectrum of brain stem gliomas through CSF-sourced circulation tumor DNA sequencing
Time of Update: 2020-06-03
Ref: Pan C, et al. Acta Neuropathol 2018 Nov 20 doi: 10.1007/s00401-018-1936-6 The cerebral glioma is a group of molecular heterogeneous diseases Because tumors are located in important functional
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Experimental Study of EGFR Inhibitor Controlling PDX Model GBM
Time of Update: 2020-06-03
Erlotinib concentration determination of subcutaneous or intracranial PDX model GBM GBM was carried out using matrix-assisted laser desorscent ionizing/ionizing mass spectrometry (MALDI MSI) and liqui
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New therapeutic target for IDH-positive glioma - DLL3
Time of Update: 2020-06-03
Mutations that encode isocitric acid dehydrogenase IDH1/IDH2 occur in low-grade gliomas and secondary glioma stomas The mutation of IDH is generally considered an early event of glioma, and the mutati
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CD34 expression and clinical pathology characteristics of low-level brain tumors associated with epilepsy
Time of Update: 2020-06-03
Ref: Giulioni M, et al World Neurosurg 2018 Sep 26 doi: 10.1016/j.wneu.2018.09.212 (E expub of print) of epilepsy-related low-level brain tumors (low-grade epilepsy-associated tumors, LEATs) includ
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Vaccine clinical trials for new diagnosis of glioblastoma
Time of Update: 2020-06-03
It is shown that APVAC1-induced T-cell function and PTP-013 can be presented via HLA peptides Of the 13 patients, 9 (69.2%) showed an answer to CD4-T cells of 1 to 2 unmutated HLA-II peptide antigens
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JNS: Non-functional GBM ultra-full excision vs. patient prognosis comparison
Time of Update: 2020-06-03
In a single-center retrospective study of non-functional GBM surgery, Tae Hoon Roh of Yonsei University in Seoul, South Korea, and others assessed whether SupTR had a longer survival period compared t
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Effect of gamma knife radiosurgery on the treatment of pituitary adenoma on the function of the pituitary gland
Time of Update: 2020-06-03
When GKRS is used to treat pituitary adenomas, the photo-dose of the pituitary handle and pituitary glands is higher than the average point dose, and the pituitary function is prone to decline I Depar
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Gamma knife phase treatment of large brain metastatic tumors
Time of Update: 2020-06-03
Ammoren Dohm, of the Winston-Salem Wake Forest School of Medicine in North Carolina, and others who use phased SRS to treat larger brain metastatic tumors can improve the prognosis of brain metastatic
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New dynamics! Tumor electric field therapy to treat glioblastoma has new results
Time of Update: 2020-06-03
Tumor Electric Field Therapy (TTFields) is a non-invasive anti-fistosion therapy In a Phase III clinical study EF-14 for newly diagnosed glioblastoma patients, TTFields and TTFields (TTFields / TMZ) c
