Science sub-journal! Cancer cells rely on the original energy generation pathway to multiply and spread.

NEW YEAR (UPI) -- In order to speed up their rapid proliferation of tumor cells rely on glycoenzyme, which is a primitive metabolic pathway cancer can easily use to get energy to grow and spreadGlysis is the oldest form of energy produced by living cellsIt existed for billions of years before the accumulation of oxygen on Earth was the first type of energy production on Earth in primitive life formsThis process involves glucose decomposition to provide energy for cellular metabolic activityThe same is true for bacteria that use sugar to solve more complex organisms such as plants and animalsHowever, the latter has developed more complex forms of energy production although it still has sugar enzymes with lower energy yieldsFor example, electron transfer chains produce more energy molecules than glycoenzymesHowever, many types of tumor cells prioritize the use of glycoenzymes to provide sufficient energy for growth and proliferationPhoto Credit: Cancer Science Group, University of Southampton School of Medicine, UK, and report that high glycoenzyme rates in cancer cells remain a recognized feature of many human tumorsThe energy production process provides cancer cells with metabolites that these metabolites can act as precursors to the anabolic pathwayIn an article published in the journal, and a group of cancer researchers found that in in vitro breast cancer models they were able to find something surprising new that they called glycoenzyme stress responseGenes carry a blueprint for a protein called tumor proteinsThis protein plays a key role in regulating cell activity such as cell division and cell deathStudies have long shown that mutations can cause cancer cells to grow and spread"The basic aerobic sugar enzyme effect is a characteristic of cancer cells that is usually caused by mutations in the cancer gene and the anti-cancer gene," he wroteIt has a number of consequences for tumor cells, including the ability to produce less dependence on oxygen and thus the potentially destructive reactive oxygen produced by the mitochondrial electron transfer chain"The century has shown that cancer cells cultured have high glucose intake and lactic acid secretion rates even when oxygen is not needed These three characteristics of glucose intake, lactic acid secretion and oxygen-free energy creation are the signs of effect It was a German scientist at the beginning of the century who first studied sea urchin eggs but turned his attention to mouse tumors This shift has had a lasting impact on the discipline of cancer biology, especially in understanding the energy generation and use of tumor cells It is noted that cancer cells promote their own growth by absorbing large amounts of glucose from the host's blood Today's positron emission scans can help identify cancer by locating areas where human cells consume a lot of glucose These cells are easily identified as cancer cells because of their insatiable appetite for glucose Photo Source: In addition, cancer cells always choose the ancient metabolic pathway glycoenzyme to produce energy Realizing that cancer cells have found a way to ensure their survival by developing the oldest form of energy production on Earth It is estimated that there are effects in all cancers Now the team at the University of Southampton has developed a new understanding of the energy production of cancer cells The researchers found that the protein is regulated by "oxygen-demand sugar enzymes" in cancer cells This is a further mediated family dependency on transcription regulation which was never anticipated "By providing glucosolphosphate enzymes for the glycophosphate pathway, it also promotes the generation of also archetypal nicotinamide adenine di nucleotide phosphate to provide reductive equivalents for the reactive oxygen species conservation pathway," the team wrote () References: : :