-
Br J Surg: Can Child-Pugh Class B liver cirrhosis patients undergo laparoscopic liver resection?
Time of Update: 2021-03-20
1093/bjs/znaa041" target="_blank" rel="noopener">Laparoscopic and open liver resection for hepatocellular carcinoma with Child-Pugh B cirrhosis: multicentre propensity score-matched study .
1093/bjs/znaa041" target="_blank" rel="noopener">Laparoscopic and open liver resection for hepatocellular carcinoma with Child-Pugh B cirrhosis: multicentre propensity score-matched study in this message
-
Cancer Discov: Efficacy and safety of new EGFR inhibitor Mobocertinib for NSCLC patients with EGFRex20ins mutation
Time of Update: 2021-03-20
CD-20-1598">Activity and Safety of Mobocertinib (TAK-788) in Previously Treated Non-Small Cell Lung Cancer With EGFR Exon 20 Insertion Mutations From a Phase 1/2 Trial .
-
Clin Cancer Res: Phase 3 trial | Cardiotoxicity of adriamycin therapy in patients with advanced soft tissue sarcoma
Time of Update: 2021-03-20
In the case of combined use with the cardioprotective agent dexrazoxane, the cumulative dose of doxorubicin can be very high (>450 mg/m2), and the incidence of cardiotoxicity is low.
-
Ann Oncol: Intracranial and extracranial efficacy of loratinib in ALK-positive NSCLC patients treated with second-generation TKI
Time of Update: 2021-03-20
This study evaluated the overall, intracranial and extracranial efficacy of loratinib for advanced ALK-positive NSCLC after treatment with second-generation ALK TKIs. In the ongoing phase II study (NCT01970865), patients with ALK-positive advanced NSCLC who had received more than one second-generation ALK TKI±chemotherapy were included in the extended cohort (EXP) based on treatment history.
-
Cell Death Differ: GLI1 mediates the occurrence and development of chondrosarcoma through mTOR/S6K1 signaling cascade
Time of Update: 2021-03-20
Simultaneous inhibition of MVP and GLI1 significantly inhibits the growth of CSIn this study, the researchers confirmed that GLI1 participates in the SMO-independent signaling pathway in CS cells.
1038/s41418-021-00749-4">Constitutive GLI1 expression in chondrosarcoma is regulated by major vault protein via mTOR/S6K1 signaling cascade .
-
American Association for Cancer Research: Sugary drinks increase the risk of death of breast cancer patients by nearly 90%!
Time of Update: 2021-03-20
To this end, researchers from the State University of New York at Buffalo conducted a comprehensive analysis of the impact of SSB on the risk of death in breast cancer patients, and the results were published in the American Association for Cancer Research ( AACR ) journal "Cancer Epidemiology, Biological Indicators and Prevention " ( Cancer Epidemiology, Biomarkers & Prevention ) magazine.
-
Eur Radiol: Elastography to distinguish pancreatic cancer from autoimmune pancreatitis!
Time of Update: 2021-03-20
Recently, a study published in the journal European Radiology prospectively studied the stiffness and fluidity of pancreatic ductal adenocarcinoma (PDAC) and autoimmune pancreatitis (AIP) on tomographic elastography, and evaluated their role in differentiating this.
The stiffness and fluidity of PDAC, AIP and healthy pancreas were compared, as well as the diagnostic performance of tomography and conventional MRI.
-
J Immunother Cancer: Types of drug resistance and imaging changes during anti-PD-1 immunotherapy for advanced melanoma
Time of Update: 2021-03-20
The primary and secondary drug resistance defined by SITC are different clinical manifestations of melanoma patients.
com/content/9/2/e002092" target="_blank" rel="noopener">Radiological dynamics and SITC-defined resistance types of advanced melanoma during anti-PD-1 monotherapy: an independent single-blind observational study on an international cohort .
-
Eur Urol: Phase 3 | The effect of pazopanib as adjuvant therapy after nephrectomy in patients with advanced renal cell carcinoma
Time of Update: 2021-03-20
029">Adjuvant Pazopanib Versus Placebo After Nephrectomy in Patients With Localized or Locally Advanced Renal Cell Carcinoma: Final Overall Survival Analysis of the Phase 3 PROTECT Trial .
-
The mechanism of cancer recurrence revealed that cancer cells may enter a dormant state and escape chemotherapy!
Time of Update: 2021-03-20
Source: ShutterstockA new study published by Will-Cornell Medical’s scientists in the American Cancer Research Association’s Journal of Cancer Discovery shows that cancer cells can escape chemotherapy by entering a state similar to aging.
-
Eur Radiol: How different is the AI application of low-dose chest CT among radiologists?
Time of Update: 2021-03-20
Screening diagnosis Recently, a study published in the journal European Radiology evaluated the computer-assisted low-dose chest CT (LDCTs) of radiologists in the nationwide lung cancer screening (LCS) program by comparing with the retrospective analysis of the central laboratory.
-
The most complete, liver cancer 10 markers combined test comparison assessment
Time of Update: 2021-03-20
The following briefly introduces some currently available liver cancer markers:Alpha-fetoprotein (AFP)Alpha-fetoprotein (AFP)According to the regulations issued by the National Health Commission for the diagnosis and treatment of primary liver cancer (2019 edition), the current clinically most effective method for assessing the risk of hepatocellular carcinoma is serum AFP combined with ultrasound, once every 6-12 months.
-
Eur Radiol: Use MRI to evaluate the chemotherapy effect of bone tumors and evaluate survival
Time of Update: 2021-03-20
diagnosis Recently, a study published in the journal European Radiology evaluated the parameters of diffusion-weighted imaging (DWI) and dynamic enhanced magnetic resonance imaging (DCE-MRI) of the tumor and the surrounding area of OS patients, which are the tumor histology of neoadjuvant chemotherapy before surgery.
-
Eur Heart J: Analysis of re-admission of cancer patients treated with percutaneous coronary intervention due to acute myocardial infarction and bleeding within 90 days
Time of Update: 2021-03-20
do?w=%E5%BF%83%E8%A1%80%E7%AE%A1">heart blood vessels magazine field authority Eur Heart published a research article on J, this study was designed to evaluate 90 days of acute myocardial infarction (AMI) and readmission rates in cancer patients undergoing PCI bleeding.
-
Professor Lu Shun: AI multi-omics deep learning predicts the efficacy of lung cancer immunity PD-1/PD-L1
Time of Update: 2021-03-20
Based on high-quality real-world data and deep learning models, this study provides important solutions for predicting the clinical benefit of patients during lung cancer immunotherapy (PD-1/PD-L1).
-
Eur Radiol: Can spleen volume be related to liver failure after hepatocellular carcinoma resection and overall survival after surgery?
Time of Update: 2021-03-20
management Recently, a study published in the journal European Radiology proved that the spleen volume (SV) measured by preoperative CT images is related to the PHLF and overall survival (OS) of HCC patients after HR, providing new opportunities for clinical screening of HCC patients suitable for surgical treatment.
-
Lancet Sub-Journal: Here comes the evidence-absolutely necessary!
Time of Update: 2021-03-20
The study shows that investing in cancer treatment, imaging, and quality of care at the same time can produce huge health and economic benefits, especially in low- and middle-income countries.
-
JAMA Netw Open: Preferred pathological biopsy or magnetic resonance imaging for age stratization screening for adenocarcinoma?
Time of Update: 2021-03-20
In summary, in the decision analysis model of this hypothetical cohort, compared with priority screening for biopsy, the priority diagnosis approach of MRI is associated with the pros and cons of prostate cancer screening and the improvement of cost-effectiveness.
-
BMJ: Breast cancer screening once every 2 years can greatly reduce the incidence and mortality of advanced breast cancer
Time of Update: 2021-03-20
Breast Cancer Screening Researchers recently investigated the impact of clinical breast cancer screening on reducing breast cancer staging and disease mortality.
Recently, researchers investigated the impact of clinical breast cancer screening on reducing breast cancer staging and disease mortality.
-
J Urol: 18F-DCFPyL-PET/CT can accurately detect and locate the metastases of prostate cancer
Time of Update: 2021-03-20
The specificity of PSMA-targeted PET/CT to detect metastatic prostate cancer reached the predetermined primary endpoint, but the sensitivity did not.
The specificity of PSMA-targeted PET/CT to detect metastatic prostate cancer reached the predetermined primary endpoint, but the sensitivity did not.
