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    Home > Active Ingredient News > Antitumor Therapy > Eur Radiol: Can spleen volume be related to liver failure after hepatocellular carcinoma resection and overall survival after surgery?

    Eur Radiol: Can spleen volume be related to liver failure after hepatocellular carcinoma resection and overall survival after surgery?

    • Last Update: 2021-03-20
    • Source: Internet
    • Author: User
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    According to major international HCC management guidelines, liver fibrosis or cirrhosis is closely related to portal hypertension, and the presence of portal hypertension is a contraindication for HR.


    According to major international HCC management guidelines, liver fibrosis or cirrhosis is closely related to portal hypertension, and the presence of portal hypertension is a contraindication for HR.


    Recently, a study published in the journal European Radiology proved that the spleen volume (SV) measured by preoperative CT images is related to the PHLF and overall survival (OS) of HCC patients after HR, providing new opportunities for clinical screening of HCC patients suitable for surgical treatment.


    This study included 317 patients with very early/early HCC who underwent preoperative CT scan and HR surgery between January 2010 and December 2016.


    This study included 317 patients with very early/early HCC who underwent preoperative CT scan and HR surgery between January 2010 and December 2016.


    There are 72 patients with PHLF (22.


    Table 1 The relationship between clinical features and spleen size and liver failure after hepatectomy

    Table 1 The relationship between clinical features and spleen size and liver failure after hepatectomy

    Table 2 The relationship between clinical characteristics and spleen size and overall survival

    Table 2 The relationship between clinical characteristics and spleen size and overall survival

    In HCC patients, the larger the SV BSA , the higher the incidence of PHLF after hepatectomy and the worse the OS.


    In HCC patients, the larger the SV BSA , the higher the incidence of PHLF after hepatectomy and the worse the OS.


    Original source:

    Jae Seok Bae,Dong Ho Lee,Jeongin Yoo,et al.


    Jae Seok Bae,Dong Ho Lee,Jeongin Yoo,et al.
    Association between spleen volume and the post-hepatectomy liver failure and overall survival of patients with hepatocellular carcinoma after resection.
    DOI: org/10.
    1007/s00330-020-07313-7">10.
    1007/s00330-020-07313-7org/10.
    1007/s00330-020-07313-7"> 10.
    1007/s00330 -020-07313-7 Leave a message here
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