-
Clin Cancer Res: Efficacy of adjuvant imatinib therapy in GIST patients with KIT exon 9 mutations: a European multicenter retrospective study
Time of Update: 2021-10-20
This retrospective study showed that GIST patients with KIT exon 9 mutations received adjuvant imatinib treatment, and a daily dose of 800 mg did not have a better survival prognosis than 400 mg a day .
-
Exercise not only prevents cancer, but also helps patients receiving ADT suppress prostate cancer!
Time of Update: 2021-10-20
Myokine Expression and Tumor-suppressive Effect of Serum following 12 Weeks of Exercise in Prostate Cancer Patients on ADT.
Myokine Expression and Tumor-suppressive Effect of Serum following 12 Weeks of Exercise in Prostate Cancer Patients on ADT.
-
Nature: Engineered bacteria regulate tumor metabolism and promote immunotherapy effects
Time of Update: 2021-10-20
To this end, the researchers used synthetic biology methods to develop an engineered probiotic Escherichia coli Nissle 1917 strain, which can colonize tumors and continuously convert the metabolic waste products accumulated in tumors, ammonia, into L-essence Acid .
-
J Immunother Cancer: Efficacy and safety of immune checkpoint inhibitors in patients with psoriasis
Time of Update: 2021-10-20
Forty-three patients (57%) experienced exacerbation of psoriasis at a median of 44 days after ICI treatment (range 1725 days) .
Forty-three patients (57%) experienced exacerbation of psoriasis at a median of 44 days after ICI treatment (range 1725 days) .
-
Eur Urol Focus: A nomogram to predict moderate postoperative renal function loss
Time of Update: 2021-10-20
Researchers used the preoperative and surgical variables of the large multicenter data set to develop a clinical nomogram that can predict long-term RF loss after RAPN.
A Nomogram for the Prediction of Intermediate Significant Renal Function Loss After Robot-assisted Partial Nephrectomy for Localized Renal Tumors: A Prospective Multicenter Observational Study (RECORd2 Project) .
-
Lancet Oncol: Carrelizumab combined with apatinib is expected to be a salvage treatment plan for chemotherapy-refractory/recurrent gestational trophoblastic tumors!
Time of Update: 2021-10-20
All in all, the combination of carrelizumab and apatinib has shown expected anti-tumor activity and acceptable safety in high-risk chemotherapy-refractory or recurrent gestational trophoblastic tumor patients, or can be used as such The patient's rescue treatment options .
-
The three substances contained in daily necessities are likely to be accomplices of breast cancer!
Time of Update: 2021-10-20
This study used MCF-7 breast cancer cell transplantation mouse models to detect the estrogenic activity of 1-HCHPK, MBB, and MTMP to confirm the endocrine disrupting effect of light stimulants .
-
Dev Cell: What causes the death of cancer patients?
Time of Update: 2021-10-20
Recently, Professor David Bilder’s team published a research paper titled Tumor-induced disruption of the blood-brain barrier promotes host death in the Journal of Developmental Cell .
-
J Clin Oncol: Phase III clinical trial results of vincristine-topotecan-cyclophosphamide for the initial treatment of non-metastatic Ewing's sarcoma
Time of Update: 2021-10-20
Ewing sarcoma (EWS) is a rare children's cancer, which constantly adjust and improve the prognosis of conventional chemotherapy, it has also been a gradual improvement of the childRecently, a new phase III randomized controlled trial published in the Journal of Clinical Oncology, the main purpose of which is to clarify whether the addition of vincristine, topotecan and cyclophosphamide (VTC) to interval compression chemotherapy can improve previously untreated The survival prognosis of patients with non-metastatic Ewing sarcoma .
-
J Clin Oncol: The efficacy of nivolumab combined with low-dose ipilimumab in the first-line treatment of MSI-H/dMMR metastatic colorectal cancer
Time of Update: 2021-10-20
Based on the CheckMate 142 study, Nivolumab was approved by the US FDA as a single agent or combined with Ipilimumab for the treatment of high microsatellite instability/mismatch repair defects (MSI-H/dMMR) Of metastatic colorectal cancer (mCRC) that has progressed after treatment with fluoropyrimidine, oxaliplatin, and irinotecan .
-
Eur Urol: In the treatment of local prostate cancer, which is better, open radical prostatectomy or robot-assisted laparoscopic prostatectomy?
Time of Update: 2021-10-20
Recently, researchers from Sweden published an article in "Eur Urol", evaluating the function and oncology of robot-assisted laparoscopic prostatectomy (RALP) and open retropubic radical prostatectomy (RRP) after 8 years The result situation .
-
Can lung cancer care specialists improve the clinical outcome of patients?
Time of Update: 2021-10-20
An article published in the International Journal of Nursing Studies assessed whether the work practices of lung cancer nursing specialists are related to mortality and unplanned hospitalizations to complement current workforce planning and future workforce policies .
-
Prostate Cancer PD: Rezūm steam therapy for the treatment of multi-disease patients with urinary retention and catheter dependence
Time of Update: 2021-10-20
Recently, researchers from Australia published an article in "Prostate Cancer PD", investigating the safety and effectiveness of this method in the treatment of patients with recurrent urinary retention and catheter dependence, who are not suitable for surgery.
-
Professor Liu Congrong: Clinical and Pathological Interpretation of "Ovarian Cancer Test Report"
Time of Update: 2021-10-20
The results of these large-scale clinical studies indicate that HRR gene testing + HRD testing can benefit more patients and is currently the most comprehensive detection of PARP inhibitor markers for ovarian cancer .
-
Are the abbreviations of chemotherapy regimens for lung cancer, breast cancer, and gastrointestinal cancer confusing?
Time of Update: 2021-10-20
To this end, the editor compiled the chemotherapy regimens for tumors in the 2021 CSCO and NCCN guidelines in the form of tables, involving lung cancer, breast cancer , colorectal cancer ,Common tumors such as gastric cancer .
-
J Clin Oncol: Resectable T1-T2N0 oral and oropharyngeal cancer sentinel lymph node biopsy VS. Equivalence of cervical nodule resection
Time of Update: 2021-10-20
Sentinel lymph node (SN) biopsy can accurately diagnose operable oral and oropharyngeal cT1-T2N0 cancers (OC), but so far, the oncological equivalence of SN biopsy and cervical lymph node dissection (ND; standard treatment) has never been Has been evaluated .
-
Front Oncol: Anlotinib combined with PD-1 inhibitors are effective and controllable in the treatment of advanced solid tumors
Time of Update: 2021-10-20
Immune blood vesselSince January 2019, 26 patients with advanced cancer have received treatment, including lung cancer, gallbladder cancer, endometrial cancer,Gastric cancer , pancreatic cancer , penile cancer and melanoma .
-
Nature: Tumor metabolic waste is actually a "treasure"!
Time of Update: 2021-10-20
The metabolic waste in the environment is converted into L-arginine, which promotes the anti-tumor immune response of T cells, and provides a new strategy and basis for improving the effect of clinical T cell therapy .
-
Front Oncol: Effects of esophagectomy and non-esophagectomy on the long-term prognosis of patients with stage T1 esophageal cancer
Time of Update: 2021-10-20
In view of this, a team from Zhejiang University conducted a retrospective study based on the SEER database to compare the effects of esophagectomy and non-esophagectomy on the long-term survival of patients with stage T1 esophageal cancer, and to determine the risk factors that affect the prognosis of patients .
-
Sports should also "choose time"?
Time of Update: 2021-10-20
In breast cancer survivors, the afternoon rather than the morning or mixed time is related to the improvement of health, lower body muscle endurance and function .
