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    Home > Active Ingredient News > Antitumor Therapy > Eur Urol Focus: A nomogram to predict moderate postoperative renal function loss

    Eur Urol Focus: A nomogram to predict moderate postoperative renal function loss

    • Last Update: 2021-10-20
    • Source: Internet
    • Author: User
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    Partial nephrectomy (PN) is the standard surgical treatment for local kidney tumors
    .


    There are numerous advantages compared with radical nephrectomy (RN), such as (RF) retention of good renal function than RN, can reduce heart vascular morbidity and mortality of the disease, and cancer treatment does not affect the final results


    With radical nephrectomy (RN) has many advantages when compared to retain as good in terms of renal function (RF) ratio RN, can reduce heart vascular morbidity and mortality of the disease, and ultimately does not affect cancer treatment and cure nephrectomy (RN) has many advantages compared to, such as in renal function (RF) retention of better than RN, can reduce heart vascular morbidity and mortality of the disease, and cancer treatment does not affect the final results heart blood vessels

    Although robot-assisted partial nephrectomy (RAPN) is increasingly used to treat local renal tumors, there are fewer studies on the extent and predictive factors of renal function (RF) loss after RAPN, especially in long-term evaluations.
    Less
    .

    Recently, researchers from Italy published an article in "Eur Urol Focus" to investigate the predictive factors and develop a clinical nomogram to predict the final RF loss after RAPN
    .

    Investigated the predictors and developed a clinical nomogram to predict the extent of the final RF loss after RAPN.
    Investigated the predictors and developed a clinical nomogram to predict the extent of the final RF loss after RAPN.

    The researchers prospectively evaluated all patients treated with RAPN in a multicenter series (RECORd2 project)
    .

    Significant RF loss was defined as a reduction of >25% in the estimated glomerular filtration rate (eGFR) at the 48th month postoperative follow-up compared to the preoperative assessment
    .


    Univariate and multivariate logistic regression were used to analyze RF loss


    The estimated glomerular filtration rate (eGFR) at the 48th month postoperative follow-up was reduced by >25% compared to the preoperative assessment


    R&D nomogram

    R&D nomogram

    In summary, the researchers used the preoperative and surgical variables of a large multi-center data set to develop a clinical nomogram that can predict long-term RF loss after RAPN


    Researchers used the preoperative and surgical variables of the large multicenter data set to develop a clinical nomogram that can predict long-term RF loss after RAPN.


    Original source:

    Original source:

    Andrea Mari, Riccardo Tellini, Alessandro Antonelli et al.


    A Nomogram for the Prediction of Intermediate Significant Renal Function Loss After Robot-assisted Partial Nephrectomy for Localized Renal Tumors: A Prospective Multicenter Observational Study (RECORd2 Project)

     

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