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J Clin Oncol: Resectable T1-T2N0 oral and oropharyngeal cancer sentinel lymph node biopsy VS. Equivalence of cervical nodule resection

 Last Update: 2021-10-20
 Source: Internet
 Author: User

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Sentinel lymph node (SN) biopsy can accurately diagnose operable oral and oropharyngeal cT1-T2N0 cancers (OC), but so far, the oncological equivalence of SN biopsy and cervical lymph node dissection (ND; standard treatment) has never been Has been evaluated
.

In this phase III multicenter trial, a total of 307 OC patients were enrolled in the study, and they were randomly assigned to (1) ND group or (2) SN group (experimental group: in the primary tumor surgery, if it is negative, it will be performed separately Biopsy, if it is positive, then proceed to ND)
.

The main result is the neck lymph node recurrence-free survival (RFS) within 2 years

As a result, a total of 279 patients (139 ND and 140 SN) data can be analyzed
.

Within 2 years, the RFS of cervical lymph nodes was 89.

In summary, this study proved the oncology equivalence of SN and ND methods.

Original source:

Renaud Garrel.

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