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Sci Adv Tang Li's team uses chemical methods to achieve specific activation of immunomodulatory proteins in tumor tissues
Time of Update: 2021-10-01
When Sw-IM enters the tumor tissue with the blood circulation, the specific stimulation of the tumor microenvironment can effectively cut off the environmentally responsive chemical bond in the connection structure to remove the shielded polymer, thereby specifically "turning on" in the tumor tissue "The biological activity of immunomodulatory proteins .
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Decoding the rheumatism live broadcast room ①Improve the standardization of rheumatism diagnosis and treatment to benefit more rheumatism patients
Time of Update: 2021-10-01
The clinical application of hormones, immunosuppressants, and biologically targeted drugs can better control lupus, reduce the time and dose of hormone use, so that the patient's disease can be stabilized as soon as possible, while also avoiding long-term organ damage .
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Professor Yang Xiuyan: Expensive medicine is not good medicine. Why is methotrexate so classic?
Time of Update: 2021-10-01
*It is only for medical professionals to read for reference.
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The latest research reveals that there are four major differences between systemic sclerosis and overlap syndrome
Time of Update: 2021-10-01
The purpose is to compare the clinical characteristics and survival outcomes of SSc patients and SSc overlap syndrome patients in the Asian cohort study, and propose the hypothesis that the two groups of patients have different disease courses, serum antibody profiles, organ involvement, and prognosis .
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Express's first topical JAK inhibitor was approved by the FDA to treat atopic dermatitis
Time of Update: 2021-10-01
▎Incyte, editor of WuXi AppTec's content team, announced today that the US FDA has approved Opzelura (ruxolitinib) cream for short-term and non-continuous long-term treatment of patients with mild to moderate atopic dermatitis (AD) over 12 years old .
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Immunity | Li Wei/Yao Xu and other teams discovered that different human Langerhans cell subgroups coordinate their functions with each other
Time of Update: 2021-10-01
September 10, 2021, Li Wei, Fudan University, Yao Xu, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, and Li Xiao, Texas Heart Institute (The Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College is the first Unit) Joint Communication published a research paper titled "Distinct human Langerhans cell subsets orchestrate reciprocal functions and require different developmental regulation" in Immunity.
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"Lupus Nephritis Diagnosis and Treatment Specifications" released!
Time of Update: 2021-10-01
Recently, the Rheumatology Branch of the Chinese Medical Association formulated and issued the "Regulations for the Diagnosis and Treatment of Lupus Nephritis" (hereinafter referred to as the "Regulations"), which aims to improve the treatment level of LN, reduce recurrence, and improve patient prognosis .
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Small difference, big impact!
Time of Update: 2021-10-01
In a new study published on "Cell Systems" on September 17, Beijing time, a research team led by Utrecht University in the Netherlands discovered the immune diversity of the population by drawing antibody maps of healthy individuals and patients, namely Everyone has their own unique serological antibody library .
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Immunity Zhou Xi/Lulu team's collaborative research reveals a new antiviral drug development strategy targeting viral RNAi inhibitors
Time of Update: 2021-09-30
Responsible editor | Xi RNAi is a highly conserved post-transcriptional gene silencing mechanism in eukaryotes. It is also a highly effective antiviral natural immune mechanism. It is considered to
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What is the disease of leg rash with joint pain?
Time of Update: 2021-09-30
Recently, the team of Professor Chen Jianghua from the Renal Disease Center of the First Affiliated Hospital of Zhejiang University published a case in the British Medical Journal (BMJ), documenting and discussing the diagnosis and treatment of a long rash on both legs and other system discomforts .
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Professor Zhang Wen: There are endless calls, when will these "potential stocks" be approved for Sjogren's syndrome indications?
Time of Update: 2021-09-30
Although there are many types of clinical drugs, Professor Zhang Wen said At present, the treatment of pSS is far behind other common rheumatic diseases .
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How is the new drug for lupus progressing?
Time of Update: 2021-09-30
In general, compared with the placebo group, Anifrolumab significantly reduced the disease activity of SLE patients, and showed a greater efficacy advantage in multiple primary/secondary endpoints .
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Environmental exposure can induce systemic lupus erythematosus: a research express based on the results of the Jiangsu population survey
Time of Update: 2021-09-30
In order to assess the impact of environmental exposure on SLE, Nanjing scholar Chen Jiaqi and others conducted a cohort study in Jiangsu Province to examine the living environment (including air and drinking water pollution, population density, economic development, etc.
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STTT Huazhong University of Science and Technology Liu Chaohong/Lu Zhongxin reveals the underlying mechanism of immunodeficiency in patients recovering from new coronavirus infection
Time of Update: 2021-09-30
In conclusion, the study found that SARS-CoV-2 infection down-regulates the expression of CD19 in B cells by enhancing B cell metabolism, leading to immunodeficiency in recovered patients, which may provide a new intervention target for curing COVID-19 .
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"Nature": Chinese scholars reveal the key mechanism of plant immunity enhancement
Time of Update: 2021-09-30
Researchers have found that when plants respond to pathogens, the activation of NLR's TIR signal plays a vital role in enhancing the defense response during the PRR-mediated pattern triggering immune process .
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Osteoporosis is not terrible, the most serious is this complication!
Time of Update: 2021-09-30
Figure 1 The 2020 AACE diagnostic criteria for postmenopausal osteoporosis first uses FRAX to assess the risk of fracture, and then uses the BMD assessment classification IOF/ESCEO 2020 version of the guidelines to detail the low, high and very high risk OP fracture algorithm Explained and pointed out the importance of bone mineral density (BMD) in OP in postmenopausal OP in assessing fracture risk and clinical intervention nodes .
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EHJ: Use uric acid lowering drugs for gout, beware of "cardiovascular risks"!
Time of Update: 2021-09-30
Only for medical professionals to read and refer to clinical information, 1s to reach more cutting-edge clinical information, follow the clinical pharmacy channel to obtain the source of this article
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What does high erythrocyte sedimentation rate and C-reactive protein mean?
Time of Update: 2021-09-30
. Among the patients with ankylosis, the X-ray hip joint involved, the serum C-reactive protein and erythrocyte sedimentation rate were significantly higher than those with hip pain symptoms but normal X-ray .
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Immunity breakthrough!
Time of Update: 2021-09-30
This study confirmed for the first time that VTP-specific targeting of VSR can effectively release RNAi antiviral immunity in virus-infected cells and in vivo, which fully proves the physiological and functional importance of RNAi as mammalian antiviral immunity .
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J INTERN MED: Higher levels of autoantibodies against apoB100 p210 are associated with lower incidence of atrial fibrillation in women
Time of Update: 2021-09-29
High levels of autoantibodies against apoB100 p210 are associated with lower incidence of atrial fibrillation in women .
13393High levels of autoantibodies against apoB100 p210 are associated with lower incidence of atrial fibrillation in women in this message
