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J INTERN MED: Higher levels of autoantibodies against apoB100 p210 are associated with lower incidence of atrial fibrillation in women

 Last Update: 2021-09-29
 Source: Internet
 Author: User

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Atrial fibrillation (AF) is associated with inflammation of the whole body and atrial tissue
.
The level of oxidized LDL in patients with AF increases, and it is considered to be one of the important molecules that cause inflammation

Recently, an authoritative journal in the field of internal medicine published a research article in the Journal of Internal Medicine.
Researchers explored the correlation between autoantibodies against oxidized apolipoprotein B100 peptide and the incidence of AF in a large population-based cohort
.

The researchers measured the IgM and IgG levels of the natural and aldehyde-modified apoB100 peptides 210 (p210) and 45 in the plasma of 5169 participants from the Malmö diet and cancer cohort by ELISA
.

During the 21.
3-year follow-up period, the researchers recorded a total of 769 AF events
.
Individuals with higher IgM levels for natural p210 at baseline had a lower risk of AF, but this association did not persist after adjusting for age and gender

Thus, these results support the association between self-body fluid immunity and atrial fibrillation
.

These results support the association between body fluid immunity and atrial fibrillation
.
immunity

Original source:

Kari Anne Sveen.

et al.

High levels of autoantibodies against apoB100 p210 are associated with lower incidence of atrial fibrillation in women in this message

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