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Hypertension: Predictive value of pulmonary arterial compliance in patients with systemic lupus erythematosus combined with pulmonary hypertension.
Time of Update: 2020-09-01
Pulmonary hypertension is a serious complication of systemic lupus erythematosus, characterized by increased load after the right chamber, including pulmonary arterial compliance (PAC) and pulmonary vascular resistance.
results of this study show that PAC is a good predictor of mortality and clinical deterioration in patients with systemic lupus-related pulmonary hypertension.
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CELL: Can TREM2 enhance tumor anti-PD-1 immunotherapy?
Time of Update: 2020-09-01
contrast, the researchers observed TREM2 plus macrophages in 75 percent of tumors from different primary sites by screening and evaluating multicance tissue chips with 126 samples.
, TREM2 is a potential target for altering bone marrow immersion in tumors and may enhance checkpoint immunotherapy.
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To cure AIDS as the goal! FDA approves Phase I clinical treatment of GENE Technology Corporation (AGT) to advance HIV treatment program.
Time of Update: 2020-09-01
American Genenure Technology Corporation (AGT) announced today that it has received FDA approval to begin Phase I clinical trials to test the effectiveness and safety of gene therapy AGT103-T for AIDS treatment, the first human trial of AGT103-T.
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Microorganisms: Probiotics help inhibit the development of colon cancer.
Time of Update: 2020-08-31
20, 2020 /--- new research shows that probiotics can control the development of colorectal cancer (CRC).
Foey and his team tested the ability of a mixture of lactic acid bacteria (LAB) strains to affect the activity of immune cells (macrophages) and the on the development of bowel cancer.
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J Autoimmun: SARS-CoV-2 infection in patients with autoimmune rheumatoid disease in north-eastern Italy.
Time of Update: 2020-08-29
Between April 9 and April 25, 2020, after the peak of SARS-CoV-2 infection, researchers conducted a telephone survey to investigate the effects of COVID-19 on patients with systemic lupus erythematosus (SLE), systemic sclerosis (SSc), rheumatoid arthritis (RA), ANCA-related vasculitis (AAV) and adrenal inflammatory myopathy (IIM).
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Institute: New research could help treat stroke.
Time of Update: 2020-08-29
when P2X4R is overactive, it can cause a series of harmful effects in brain cells, leading to ischemic brain damage.
by blocking receptor activity, the researchers found that excessive immune responses were effectively inhibited to improve the recovery of acute and chronic strokes.
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Primary bile bile teritis (PBC) best-in-class, breakthrough drug! Clinical success of phase III of the PPAR xenon agitant seladelpar III!
Time of Update: 2020-08-28
"PBC" (Photo Source: Genfit.com) ENHANCE is a randomized, double-blind, placebo-controlled global study of 265 PBC patients who did not respond well to bear deoxycholic acid (UDCA) (at least 12 months after treatment, serum alkaline phosphatase levels (ALP) were 1.67 x normal upper limit (ULN)) or had poor tolerance to UBC.
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The 100-year-old mystery of "connected couples" has been solved.
Time of Update: 2020-08-28
, in fact, these are nothing, incredible is the breeding strategy of herring: female and male fish "blood and flesh fusion", co-prosperity symbonity.
researchers say the genes that encode these MHC molecules in permanently attached herring have largely lost their independence, as if they had abandoned immune recognition for tissue fusion.
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Nature: A new mRNA vaccine has been designed to keep the new crown virus protrusion protein in a pre-fusion image.
Time of Update: 2020-08-28
" NIAID team and members of the McLellan Laboratory at the University of Texas at Austin announced earlier this year that they had identified the molecular structure of the stabilized SARS-CoV-2 protrusion protein within weeks of receiving the gene sequence, and published the structure of the hedgehog protein in the journal Science.
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Oral new medicine for multiple sclerosis! Next-generation selective immunomodant IMU-838: significant efficacy, good safety!
Time of Update: 2020-08-28
results showed that the study reached a major endpoint: within 24 weeks of treatment, the cumulative number of combined independent magnetic resonance imaging (CUA-MRI) lesions in patients in the 45 mg dose group decreased significantly by 62% compared to the placebo group.
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Leukemia: The combination of the drug quizatini in combination with dasatinyni may be effective in the treatment of acute myeloid leukemia.
Time of Update: 2020-08-28
Enzyme inhibitors, which close the replaceable survival path of cancer cells when they bind to another TKI called dasatinib, could be more effective in promoting leukemia cell death, and the results may help researchers develop new therapies to treat AML patients with the FRT3 gene mutation.
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The first drug to carry out sexual fibrosis mesothylytic pulmonary disease (PF-ILD)! Blinger Ingehan Ofev (Nidanibu) significantly delays the decline in lung function!
Time of Update: 2020-08-28
analysis showed that Ofev reduced the annual rate of FVC decline in patients with chronic fibrosis ILD compared to placebos, independent of baseline demographic characteristics, lung function, or ILD diagnosis.
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Nature: Scientists in China have discovered that the new coronary virus S-RBD vaccine induces a protective immune response.
Time of Update: 2020-08-28
the findings were published online July 29, 2020 in the journal Nature, entitled "A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces the immunity".
A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces the immunity.
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Cell: Severe COVID-19 is characterized by abnormal regulation of bone marrow cells.
Time of Update: 2020-08-27
!--Webeditor:title"--August 7, 2020//--- In a new study, from the Charit School of Medicine in Berlin, Germany, the University of Bonn, the German Center for Neurodegenerative Diseases (DZNE) Researchers at research institutions such as the Helmholtz Infection Research Center (HZI) and the German Infection Research Center (DZIF) found that, contrary to popular belief, the severe course of COVID-19 not only leads to a strong immune response, but the immune response is in a continuous activation and suppression cycle.
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A new drug for multiple sclerosis! Novarhua once a month of ofatumab III clinical efficacy beat Sanofi oral drug Aubagio!
Time of Update: 2020-08-27
!-- Webeditor:page title"--August 07, 2020 // -- Novartis recently announced that the New England Journal of Medicine (NEJM), an international authoritative medical journal, ) Positive results from two Phase III clinical studies (ASCLEPIOS I, II) on the treatment of multiple sclerosis (RMS) with monoantigenic drug of often oatumumab (OMBI157) have been published online.
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Nature: A new study has found that the ChAdOx1 nCoV-19 vaccine prevents rhesus monkeys from developing new coronary pneumonia.
Time of Update: 2020-08-27
in a new study, researchers from the National Institute of Allergy and Infectious Diseases of the United States and research institutes such as the University of Oxford in the United Kingdom found that chAdOx1 nCoV-19, a candidate vaccine for adenovirus vectors encoding SARS-CoV-2 puncture proteins, is immunogenic in mice and can trigger powerful body fluid immune responses and cell-mediated immune responses.
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Nat Microbiol: Scientists have successfully identified the evolutionary origins of SARS-CoV-2.
Time of Update: 2020-08-27
August 9, 2020 // -- Researchers from China, Europe and the United States have reconstructed the SARS-CoV-2 virus that causes COVID-19 in a study published in the international journal Nature Microbio
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Hypertension: Long-term high blood pressure may damage the blood vessel health of the brain.
Time of Update: 2020-08-27
August 8, 2020 // -- In a recent study published in the international journal Hypertension, scientists from the University of Michigan School of Medicine and others found that long-term high blood pre
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Nature: New Discovery! Before the body infects the pathogen, the gut microorganisms may shape the body's production of a variety of antibodies!
Time of Update: 2020-08-27
researcher Limenitakis says we can use a specially designed computer program to process millions of genetic sequences that compare antibody pools in B cells, depending on whether microbes stay in the intestines or reach the bloodstream, in which case the antibody bank changes, but the way they change depends on how exposure occurs.
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Cell: Special proteins may promote cells in stress states into molecular "traffic jams" that can trigger cell suicide paths.
Time of Update: 2020-08-27
August 9, 2020 // -- When cells experience high levels of stress (such as exposure to excessive ultraviolet radiation), the nucleucleus in the cells collides and causes "traffic jams" within the cells
