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Summary table of lung cancer, targeted and immunotherapy drugs (January 2022)
Time of Update: 2022-01-08
For patients, many more patients are waiting for new life-saving drugs!The editor compiled more than 40 drugs approved by the FDA and NMPA and recommended by NCCN guidelines in the field of lung cancer targeted and immunotherapy (as of December 2021), and attached relevant information such as medical insurance payment prices and medical insurance indications .
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Express AbbVie's ADC therapy is recognized by the FDA as a breakthrough therapy for the treatment of non-small cell lung cancer
Time of Update: 2022-01-08
It is used to treat patients with advanced/metastatic epidermal growth factor receptor (EGFR) wild-type non-squamous non-small cell lung cancer (NSCLC) who have disease progression and c-Met overexpression during or after platinum drug treatment .
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Ann Oncol: Patients with limited-stage small cell lung cancer (LD-SCLC) treated with nivolumab and ipilimumab after concurrent chemoradiotherapy + PCI can not improve the prognosis of patients
Time of Update: 2022-01-08
Therefore, some investigators have launched a phase II study ETOP/IFCT 4-12 STIMULI to evaluate the efficacy of nivolumab+ipilimumab treatment in patients with limited-stage small cell lung cancer (LD-SCLC) after concurrent radiotherapy and chemotherapy + PCI .
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J Clin Oncol: PD-1 and CTLA-4 dual blocking second-line treatment of advanced cervical cancer has a significant effect
Time of Update: 2022-01-08
Recently, the Journal of Clinical Oncology published a research result, mainly to evaluate the efficacy and safety of PD-1 inhibitor Balstilimab + CTLA-4 inhibitor zalifrelimab in the treatment of patients with recurrent and or metastatic cervical cancer who have progressed from first-line platinum chemotherapy.
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Science Sub-Journal: Penn and Yale University jointly develop a new field of mRNA vaccines
Time of Update: 2022-01-08
Drew Weissman of the University of Pennsylvania has developed an mRNA-based vaccine designed to prevent Lyme disease by targeting the salivary protein of ticks .
The research results were published in Science Translational Medicine under the title "mRNA vaccination induces tick resistance and prevents transmission of the Lyme disease agent" .
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European Radiology: Application of functional MRI in the characterization of benign and malignant parotid tumors
Time of Update: 2022-01-08
Pleomorphic adenomas (PAs), Warthin tumors (WTs) and malignant tumors (MTs) are the most common types of parotid gland tumors . They account for 65%, 15-20%, and 15-30% of parotid gland tumors, respe
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Eur Urol: Evaluation of the efficacy and safety of stereotactic radiotherapy and short-term pembrolizumab in the treatment of oligometastatic renal cell carcinoma
Time of Update: 2022-01-08
Stereotactic ablation radiotherapy (SABR) is the treatment of oligometastasis An option for clear cell renal cell carcinoma (ccRCC), but limited due to lack of prospective clinical trial dataRecently, researchers from Australia published an article in the journal Eur Urol.
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Ther Adv Med Oncol: A retrospective study by Professor Zhong Zhong Shiming’s team found that lenvatinib + teriprizumab + hepatic arterial infusion chemotherapy (HAIC) can improve the prognosis of patients with advanced hepatocellular carcinoma
Time of Update: 2022-01-08
Studies have shown that compared with lenvatinib alone, the LeToHAIC group (Lenvatinib + toripalimab +HAIC) can improve the prognosis of patients with advanced hepatocellular carcinoma, and the toxicity is tolerable .
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Radiology: Radiology model, so that clinical stage I lung adenocarcinoma has nowhere to hide!
Time of Update: 2022-01-08
Lung cancer is one of the most common cancers and the leading cause of cancer deaths worldwide . Among them , adenocarcinoma is the most common histological subtype . Surgical resection provides the
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Nature: A magical discovery!
Time of Update: 2022-01-08
"Non-genetic determinants of malignant clonal fitness at single-cell resolution" successfully used a new type of cell barcode technology to track and analyze the behavior of cancer cells .
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European Radiology: The value of MRI in differentiating benign and malignant pancreatic mucinous cystic tumors
Time of Update: 2022-01-08
Recently, published in the E uropean a journal Radiology study to assess the value of MRI in differentiating benign and malignant mucinous cystic pancreatic tumors , provides a valuable reference for the development of treatment programs preoperative assessment clinic .
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Imaging of massive intrahepatic single-tube cell carcinoma
Time of Update: 2022-01-08
At present, only hepatectomy has a clear effect on prolonging survival time for patients with resectable intrahepatic cholangiocarcinoma .
At present, only hepatectomy has a clear effect on prolonging survival time for patients with resectable intrahepatic cholangiocarcinoma .
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Clinical Guidelines for Radiotherapy of Small Cell Lung Cancer in China (2020 Edition)
Time of Update: 2022-01-08
Source: Chinese Journal of Radiation OncologySource: Chinese Journal of Radiation Oncology Source: Chinese Journal of Radiation OncologyreferencesReferences ReferencesChinese Medical Association Radiation Oncology Therapeutics Branch, Chinese Medical Doctor Association Radiation Oncology Therapeutics Branch, Chinese Anti-Cancer Association Radiotherapy Professional Committee, Chinese Clinical Oncology Society Radiotherapy Expert Committee.
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EBCAM: Curative Effect Observation of Modified Zishen Tongguan Decoction Combined with Acupuncture on Urinary Retention after Cervical Cancer Operation
Time of Update: 2022-01-08
statisticsConclusion: Modified Zishen Tongguan Decoction combined with acupuncture can significantly improve the therapeutic effect, bladder compliance and urine function of patients with urinary retention after cervical cancer surgery .
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The protagonist of the "blood test for cancer" scam was convicted!
Time of Update: 2022-01-08
After several years of development, the company's equipment claims to be able to detect hundreds of indicators with just a few drops of blood, and screen out a variety of diseases including cancer and diabetes .
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BMC Cancer: For locally advanced esophageal cancer, such as cT1N+ and cT2Nany, is neoadjuvant therapy or adjuvant therapy better?
Time of Update: 2022-01-08
Differences in OS of different treatment options in the adjuvant therapy (AT) group OS difference of different treatment options in the adjuvant treatment (AT) group OS difference of different treatment options in the adjuvant treatment (AT) group In summary, studies have shown that NT has no obvious advantage over AT in patients with cT1N+ and cT2N any esophageal cancer .
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J Urol: Comparison of cardiotoxicity between surgical castration and medical castration in prostate cancer patients
Time of Update: 2022-01-08
Recently, a researcher published an article in the journal J Urol comparing the risk of major adverse cardiovascular and cerebrovascular events (MACCEs) in prostate cancer patients undergoing surgical castration or GnRH therapy .
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European Radiology: After the diagnosis of lung cancer, are there brain metastases?
Time of Update: 2022-01-08
This study shows that CT-derived imaging features and clinical stages, lung cancer subtypes, and EGFR mutations are predictors of brain metastasis in newly diagnosed NSCLC patients, showing different associations according to the resectability of the tumor .
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Express treatment of advanced lung cancer, tumor suppressor gene therapy/Keytruda combination obtained FDA fast track qualification
Time of Update: 2022-01-08
S. FDA has granted the gene therapy Reqorsa Fast Track Designation (FTD), and Merck (MSD)'s blockbuster PD-1 inhibitor Keytruda (pembrolizumab, pembrolizumab) Combined use to treat patients with stage III or IV non-small cell lung cancer (NSCLC) whose histologically confirmed unresectable .
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Nat Rev Clin Oncol: Cancer-related accelerated aging and biological behavior modifiers: a framework for research and clinical treatment
Time of Update: 2022-01-08
We recommend that these host factors be considered in cancer-related age acceleration models, and interventions aimed at reducing stress, improving sleep health, increasing physical activity, controlling weight, and/or reducing alcohol and tobacco use as promising solutions Method of research .
