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    Home > Active Ingredient News > Antitumor Therapy > Radiology: Radiology model, so that clinical stage I lung adenocarcinoma has nowhere to hide!

    Radiology: Radiology model, so that clinical stage I lung adenocarcinoma has nowhere to hide!

    • Last Update: 2022-01-08
    • Source: Internet
    • Author: User
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    Lung cancer is one of the most common cancers and the leading cause of cancer deaths worldwide
    .


    Among them , adenocarcinoma is the most common histological subtype


    Lung cancer is one of the most common cancers and the leading cause of cancer deaths worldwide


    Recently, image-based radiomics has attracted more and more attention as an emerging method to quantify tumor heterogeneity, and may provide potential clinical imaging features for patient stratification


    Recently, he published in a journal Radiology study the use of CT radiation group learning model based on different region of interest (VOIs), including tumor and peritumoral area , assessing their prognosis to improve clinical stage I lung adenocarcinoma accuracy entity , To provide more accurate guidance for the clinic and assist the clinic to predict the prognosis of early-stage lung cancer patients more accurately, and to provide data support for the formulation of individualized and refined treatment plans earlier


    This retrospective study included patients with clinical stage I solid lung adenocarcinoma from two hospitals (center 1 and center 2)


    A total of 334 patients were enrolled (204 and 130 in No.


     

    The figure performs multivariate Cox regression analysis on selected radiomic features in four regions: aGTV, bPTV0~+3, cPTV-3~+3, dPTV0~+6 .
    .
    Means p<0.
    05, * means p<0.
    01, ** means p<0.
    001, *** means p<0.
    0001, determined by DeLong test .
     

    The figure performs multivariate Cox regression analysis on selected radiomic features in four regions: aGTV, bPTV0~+3, cPTV-3~+3, dPTV0~+6 .


    .
    Means p<0.


    This study shows that , compared with the VOI based on 3mm or 6mm inside and outside the tumor, the radiomic model based on the visible tumor boundary of 6mm (PTV-3~+3) predicts the prognosis of clinical stage I solid lung adenocarcinoma Aspect is more accurate


    Original source :

    Kunfeng Liu , Kunwei Li , Tingfan Wu ,et al .


    Improving the accuracy of prognosis for clinical stage I solid lung adenocarcinoma by radiomics models covering tumor per se and peritumoral changes on CT.
    DOI: 10.


    Liu Kunfeng Kunwei of Li Tingfan Wu , et Al 10.
    1007 / s00330-021-08194-0 10.
    1007 / s00330-021-08194-0 in this message
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