European Radiology: After the diagnosis of lung cancer, are there brain metastases?

Brain metastasis is a common complication of non-small cell lung cancer ( NSCLC ), with a total incidence of 40% during the course of the disease and 15-20% at the time of initial diagnosis
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Brain metastasis indicates a poor prognosis and is of great significance in NSCLC patients.

Brain metastasis is a common complication of non-small cell lung cancer ( NSCLC ), with a total incidence of 40% during the course of the disease and 15-20% at the time of initial diagnosis

Currently, the indications for brain imaging of newly diagnosed NSCLC patients are based on clinical staging

Recently, published in the E uropean a journal Radiology study in NSCLC patients with newly diagnosed, according to the disease resectability were dichotomy assessment to find out from the chest CT and clinical features of staging can be assessed predictors of brain metastases , as The accurate clinical staging and the formulation of personalized treatment plan provide reference basis .
 

In this study , NSCLC patients who were newly diagnosed with clinical stage II-IV from November 2017 to October 2018 were enrolled.

The study included 911 NSCLC patients (mean age, 65 ± 11 years; 620 men), of which 194 patients were diagnosed with brain metastases

FIG.
A Axial enhanced CT image shows the right lung lobe mass on a 77 mm, lobulated edges .
b The mediastinal window shows pleural effusion and nodular thickening of the pleura (arrow), indicating pleural metastasis .
c mediastinal crown under the window set bit display right lung and right lung lower lobe lymph nodes (arrow) next to the trachea .
Taken together, the clinical stages of the patient are T4, N2, and M1a .
The brain MRI examination used for staging is negative for brain metastases .
 

FIG.

A Axial enhanced CT image shows the right lung lobe mass on a 77 mm, lobulated edges .
b The mediastinal window shows pleural effusion and nodular thickening of the pleura (arrow), indicating pleural metastasis .
c mediastinal crown under the window set bit display right lung and right lung lower lobe lymph nodes (arrow) next to the trachea .
Taken together, the clinical stages of the patient are T4, N2, and M1a .
The brain MRI examination used for staging is negative for brain metastases .

This study shows that CT-derived imaging features and clinical stages, lung cancer subtypes, and EGFR mutations are predictors of brain metastasis in newly diagnosed NSCLC patients, showing different associations according to the resectability of the tumor

Original source :

Sohee Park , Sang Min Lee , Yura Ahn , et al .

Identification of predictors for brain metastasis in newly diagnosed non-small cell lung cancer: a single-center cohort study.
DOI: 10.
1007/s00330-021-08215-y

Park Sohee Sang Min Lee Yura Ahn , et Al 10.
1007 / Y-s00330-021-08215 10.
1007 / s00330-021-08215-Y in this message