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A person's blood type may be associated with their risk of early stroke, according to a new meta-analysis led by researchers at the University of Maryland School of Medicine (UMSOM)
"The number of early strokes is on the rise
He and his colleagues conducted a meta-analysis of 48 studies on genetic and ischemic stroke, including 17,000 stroke patients and nearly 600,000 healthy controls who had never experienced a stroke
The study found that people with early strokes were more likely to have type A blood and less likely to have type O (the most common blood type) compared to people with advanced strokes and people who had never had a stroke
"Our meta-analysis looked at people's genetic profiles and found an association between blood type and risk of early-onset stroke
Dr Kittner said: "We still don't know why blood type A is associated with a higher risk, but it may be related to clotting factors, such as platelets, vascular lining cells and other circulating proteins, which are involved in the formation of blood clots.
One limitation of this study is the relative lack of diversity among the participants
"This study raises an important question that warrants a more in-depth investigation of how our genetically predetermined blood type plays a role in early stroke risk," said Mark T.
This research was supported by the National Institutes of Health and the Department of Veterans Affairs
