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Pfizer has submitted an Emergency Use Authorization application to the U.
Moncef Slaoui, chief operating officer of Operation Curvature Speed, the U.
At the same time, BD (Becton, Dickinson and Company), one of the largest suppliers of injection equipment in the United States, and ApiJect Systems, a maker of prefilled syringes, are accelerating the supply of hundreds of millions of syringes to support global vaccination
BD supplies hundreds of millions of vaccine syringes
BD supplies hundreds of millions of vaccine syringesTo date, BD has committed more than 800 million needles and syringes to 12 countries and NGOs conducting COVID-19 vaccination campaigns
BD said on its company blog website, "Needles and syringes look simple, but they are highly calibrated, highly precise and intelligent drug delivery devices.
The 800 million vaccine syringes announced by BD on its official website are mainly provided to the United States, Canada, the United Kingdom, Spain, the Netherlands, Germany, Saudi Arabia and Australia and other countries and regions
According to BD, the entire syringe production process includes the following steps:
Plastic resin pellets are heated, melted and injected into a mold to form the plastic parts of a syringe - the barrel and plunger rod
Plastic resin pellets are heated, melted and injected into a mold to form the plastic parts of a syringe - the barrel and plunger rod
The tube is then shrunk using a drawing metalworking process until it reaches the proper wall thickness and gauge (outside diameter measurement), and then cut to length
The needle parts (cannula, hub and shield) and syringe parts (syringe barrel, plunger rod and stopper) are separately fed into a high-speed assembly machine and the final product into a packaging machine
Assembled syringes are immediately placed into on-site sterilized cartons, stacked on pallets and loaded onto trucks
The BD Supply Chain team will then ship the syringes to a distribution center at McKesson, a U.
However, this time Pfizer said it does not plan to use McKesson to distribute its COVID-19 vaccine, and will use its own distribution system to provide COVID-19 vaccines directly to healthcare providers
BD says billions of needles and syringes are produced for the U.
For the new order from the U.
ApiJect secures $590 million loan to accelerate prefilled syringe production
ApiJect secures $590 million loan to accelerate prefilled syringe productionApiJect Systems, a provider of pharmaceutical prefilling solutions, has received a $590 million loan from the U.
Prefilled syringes by ApiJect Systems
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According to reports, the ApiJect Gigafactory park invested by the loan will be located in Research Triangle Park, North Carolina, covering an area of 1 million square feet
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The facility will have the world's largest pharmaceutical pre-fill facility, capable of producing up to 3 billion single-dose pre-filled syringes per year
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This new facility combines proven sterile pharmaceutical packaging technology, Blow Fill Seal (BFS), with ApiJect's proprietary syringe-specific needle technology to reliably and safely package pharmaceuticals in BFS prefilled syringes
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Using medical grade plastic resin, BFS can manufacture, fill and seal 12-25 prefilled syringes every 3 seconds per line
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ApiJect Gigafactory park renderings
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ApiJect Systems said the Gigafactory will have Biosafety Level 2 (BSL-2) capabilities and support vaccines that require standard refrigeration or cryogenic storage to -70°C
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Each line is produced in isolation, allowing up to 15 different drugs to be packaged simultaneously
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In addition to the BFS line, the ApiJect campus will have two separate special-purpose drug manufacturing facilities to process drugs such as next-generation antibiotics and cytotoxic drugs, as well as an on-site needle factory to secure this important medical supply chain project domestic supply
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