There are 140,000 viruses living in the human gut

。，（EMBL-EBI）14，。《》28000。，。，，，。，，、。，，。，DNA，280602898，14。“，。”、EMBL-EBIAlexandre Almeida，DNA，。，，，Gubaphage。Gubaphage，2014crAssphage。，Gubaphage。"An important aspect of our work is to ensure that the reconstructed viral genome is of the highest quality. Strict quality control processes and machine learning methods can reduce pollution and obtain a highly complete viral genome. High-quality viral genomes provide a better understanding of how viruses are The role of the gut microbiota paves the way, including the discovery of new treatments, such as antibacterial agents derived from bacteriophages," said Luis F. Camarillo-Guerrero of the Weikang Sanger Institute, the first author of the paper. The research results form the basis of the intestinal phage database, which contains 142809 non-redundant phage genomes, which is a very valuable resource for those engaged in phage-related research. One of the authors, Dr. Trevor Lawley Wellcome Sanger Institute, said: "This high-quality, large-scale human enterovirus directory, can be used as study groups to guide future virus ecology and evolutionary analysis of the blueprint. " 　　Relevant papers Information: https://doi. org/10. 1016/j. cell. 2021. 01. 029      Disclaimer: This article only represents the author's personal views and has nothing to do with China Probiotics. com. The originality and the text and content stated in the article have not been verified by this site. This site does not make any guarantee or commitment to the authenticity, completeness, and timeliness of this article, all or part of the content, and the text. Please readers for reference only, and please Verify the relevant content yourself.      Copyright Notice    1. Some of the reprinted articles on this site are not original, and the copyright and liability belong to the original author. 2. All reprinted articles, links and pictures on this website are for the purpose of conveying more information, and clearly indicate the source and author. Media or individuals who do not want to be reprinted can contact us for infringement information that can provide sufficient evidence , Bio149 will be deleted within 12 hours after confirmation. 3. Users are welcome to post original articles to 86371366@qq. com, and publish them to the homepage after review. The copyright and liability belong to the sender.

　　Viruses are the most numerous organisms on the planet.
Now, researchers at the Wellcome Sanger Institute and the European Institute of Bioinformatics (EMBL-EBI) have identified more than 140,000 viruses living in human intestines, more than half of which have never been seen before.
　　A paper published in Cell recently analyzed more than 28,000 gut microbiome samples collected in different parts of the world.
The number and diversity of viruses discovered by researchers is surprisingly high.
These data open up new research avenues for understanding how enteroviruses affect human health.
　　In the human intestine, in addition to bacteria, thousands of viruses called bacteriophages that can infect bacteria also live there.
It is well known that the imbalance of the gut microbiota can lead to diseases such as inflammatory bowel disease, allergies and obesity.
However, little is known about the role of intestinal bacteria and related bacteriophages in human health and disease.
　　This time, using a DNA research method called metagenomics, the researchers studied and recorded the diversity of virus species found in 28060 human intestinal metagenomics and 2898 bacterial isolated genomes, confirming that they live in the human intestine.
There are more than 140,000 viruses in the road.
　　"Not all viruses are harmful.
They are an indispensable part of the intestinal ecosystem.
" One of the authors of the paper, Alexandre Almeida of the Wellcome Sanger Institute and EMBL-EBI said that most of the viruses they found Viruses all use DNA as genetic material, and these samples are mainly from healthy individuals without specific diseases.
　　Among the tens of thousands of viruses discovered, a new epidemic branch was discovered.
This is a group of viruses that are thought to have a common ancestor, and researchers call it Gubaphage.
Gubaphage was found to be the second most common branch of the virus in the human intestine, second only to crAssphage, which was discovered in 2014.
　　The two viruses seem to infect similar types of human intestinal bacteria, but the exact function of Gubaphage is not yet clear.
　　"An important aspect of our work is to ensure that the reconstructed viral genome is of the highest quality.
Strict quality control processes and machine learning methods can reduce pollution and obtain a highly complete viral genome.
High-quality viral genomes provide a better understanding of how viruses are The role of the gut microbiota paves the way, including the discovery of new treatments, such as antibacterial agents derived from bacteriophages," said Luis F.
Camarillo-Guerrero of the Weikang Sanger Institute, the first author of the paper.
　　The research results form the basis of the intestinal phage database, which contains 142809 non-redundant phage genomes, which is a very valuable resource for those engaged in phage-related research.
　　One of the authors, Dr.
Trevor Lawley Wellcome Sanger Institute, said: "This high-quality, large-scale human enterovirus directory, can be used as study groups to guide future virus ecology and evolutionary analysis of the blueprint.
" 　　Relevant papers Information: https://doi.
org/10.
1016/j.
cell.
2021.
01.
029

---

　　Viruses are the most numerous organisms on the planet.
Now, researchers at the Wellcome Sanger Institute and the European Institute of Bioinformatics (EMBL-EBI) have identified more than 140,000 viruses living in human intestines, more than half of which have never been seen before.
　　A paper published in Cell recently analyzed more than 28,000 gut microbiome samples collected in different parts of the world.
The number and diversity of viruses discovered by researchers is surprisingly high.
These data open up new research avenues for understanding how enteroviruses affect human health.
　　In the human intestine, in addition to bacteria, thousands of viruses called bacteriophages that can infect bacteria also live there.
It is well known that the imbalance of the gut microbiota can lead to diseases such as inflammatory bowel disease, allergies and obesity.
However, little is known about the role of intestinal bacteria and related bacteriophages in human health and disease.
　　This time, using a DNA research method called metagenomics, the researchers studied and recorded the diversity of virus species found in 28060 human intestinal metagenomics and 2898 bacterial isolated genomes, confirming that they live in the human intestine.
There are more than 140,000 viruses in the road.
　　"Not all viruses are harmful.
They are an indispensable part of the intestinal ecosystem.
" One of the authors of the paper, Alexandre Almeida of the Wellcome Sanger Institute and EMBL-EBI said that most of the viruses they found Viruses all use DNA as genetic material, and these samples are mainly from healthy individuals without specific diseases.
　　Among the tens of thousands of viruses discovered, a new epidemic branch was discovered.
This is a group of viruses that are thought to have a common ancestor, and researchers call it Gubaphage.
Gubaphage was found to be the second most common branch of the virus in the human intestine, second only to crAssphage, which was discovered in 2014.
　　The two viruses seem to infect similar types of human intestinal bacteria, but the exact function of Gubaphage is not yet clear.
　　"An important aspect of our work is to ensure that the reconstructed viral genome is of the highest quality.
Strict quality control processes and machine learning methods can reduce pollution and obtain a highly complete viral genome.
High-quality viral genomes provide a better understanding of how viruses are The role of the gut microbiota paves the way, including the discovery of new treatments, such as antibacterial agents derived from bacteriophages," said Luis F.
Camarillo-Guerrero of the Weikang Sanger Institute, the first author of the paper.
　　The research results form the basis of the intestinal phage database, which contains 142809 non-redundant phage genomes, which is a very valuable resource for those engaged in phage-related research.
　　One of the authors, Dr.
Trevor Lawley Wellcome Sanger Institute, said: "This high-quality, large-scale human enterovirus directory, can be used as study groups to guide future virus ecology and evolutionary analysis of the blueprint.
" 　　Relevant papers Information: https://doi.
org/10.
1016/j.
cell.
2021.
01.
029

---

　　Viruses are the most numerous organisms on the planet.
Now, researchers at the Wellcome Sanger Institute and the European Institute of Bioinformatics (EMBL-EBI) have identified more than 140,000 viruses living in human intestines, more than half of which have never been seen before.
　　A paper published in Cell recently analyzed more than 28,000 gut microbiome samples collected in different parts of the world.
The number and diversity of viruses discovered by researchers is surprisingly high.
These data open up new research avenues for understanding how enteroviruses affect human health.
　　In the human intestine, in addition to bacteria, thousands of viruses called bacteriophages that can infect bacteria also live there.
It is well known that the imbalance of the gut microbiota can lead to diseases such as inflammatory bowel disease, allergies and obesity.
However, little is known about the role of intestinal bacteria and related bacteriophages in human health and disease.
　　This time, using a DNA research method called metagenomics, the researchers studied and recorded the diversity of virus species found in 28060 human intestinal metagenomics and 2898 bacterial isolated genomes, confirming that they live in the human intestine.
There are more than 140,000 viruses in the road.
　　"Not all viruses are harmful.
They are an indispensable part of the intestinal ecosystem.
" One of the authors of the paper, Alexandre Almeida of the Wellcome Sanger Institute and EMBL-EBI said that most of the viruses they found Viruses all use DNA as genetic material, and these samples are mainly from healthy individuals without specific diseases.
　　Among the tens of thousands of viruses discovered, a new epidemic branch was discovered.
This is a group of viruses that are thought to have a common ancestor, and researchers call it Gubaphage.
Gubaphage was found to be the second most common branch of the virus in the human intestine, second only to crAssphage, which was discovered in 2014.
　　The two viruses seem to infect similar types of human intestinal bacteria, but the exact function of Gubaphage is not yet clear.
　　"An important aspect of our work is to ensure that the reconstructed viral genome is of the highest quality.
Strict quality control processes and machine learning methods can reduce pollution and obtain a highly complete viral genome.
High-quality viral genomes provide a better understanding of how viruses are The role of the gut microbiota paves the way, including the discovery of new treatments, such as antibacterial agents derived from bacteriophages," said Luis F.
Camarillo-Guerrero of the Weikang Sanger Institute, the first author of the paper.
　　The research results form the basis of the intestinal phage database, which contains 142809 non-redundant phage genomes, which is a very valuable resource for those engaged in phage-related research.
　　One of the authors, Dr.
Trevor Lawley Wellcome Sanger Institute, said: "This high-quality, large-scale human enterovirus directory, can be used as study groups to guide future virus ecology and evolutionary analysis of the blueprint.
" 　　Relevant papers Information: https://doi.
org/10.
1016/j.
cell.
2021.
01.
029

---