The Production Process of (6-Chloro-pyridazin-3-yl)-piperidin-3-ylMethyl-aMine hydrochloride, 98+% C10H16Cl2N4, MW: 263.17

Introduction:

In the chemical industry, the production process of various chemical compounds is a crucial aspect that determines the quality and efficiency of the final product.
Piperidine derivatives, such as (6-chloro-pyridazin-3-yl)-piperidin-3-ylMethyl-aMine hydrochloride, are important compounds with a wide range of applications in medicine, agriculture, and other industries.
In this article, we will discuss the production process of (6-chloro-pyridazin-3-yl)-piperidin-3-ylMethyl-aMine hydrochloride, 98+% C10H16Cl2N4, MW: 263.
17.

The Starting Materials:

The production of (6-chloro-pyridazin-3-yl)-piperidin-3-ylMethyl-aMine hydrochloride begins with the synthesis of the starting materials, which are 6-chloro-pyridazine and piperidine-3-ylMethyl-amine.
6-chloro-pyridazine is synthesized by treating aminopyridine with chloroform under suitable conditions.
Piperidine-3-ylMethyl-amine is synthesized by reacting dimethylamine with piperidine in the presence of a catalyst.

The Synthesis of (6-chloro-pyridazin-3-yl)-piperidin-3-ylMethyl-aMine hydrochloride:

The synthesis of (6-chloro-pyridazin-3-yl)-piperidin-3-ylMethyl-aMine hydrochloride involves the reaction of 6-chloro-pyridazine and piperidine-3-ylMethyl-amine in the presence of a suitable catalyst.
The reaction takes place in a suitable solvent, such as water or ethanol, and is typically carried out at a temperature of 100-150°C.
The reaction can be catalyzed by various reagents, such as pyridine, picoline, or DBU (1,8-diazabicyclo[5.
4.
0]undec-7-ene).

The Purification of (6-chloro-pyridazin-3-yl)-piperidin-3-ylMethyl-aMine hydrochloride:

After the synthesis of (6-chloro-pyridazin-3-yl)-piperidin-3-ylMethyl-aMine hydrochloride, the product is typically purified by recrystallization or chromatography.
Recrystallization involves dissolving the product in a suitable solvent, such as ethanol or acetonitrile, and allowing it to cool slowly, leading to the formation of pure crystals.
Chromatography involves passing the product through a column filled with a suitable stationary phase, such as silica gel or alumina, which adsorbs the impurities while allowing the pure compound to pass through.

The Characterization of (6-chloro-pyridazin-3-yl)-piperidin-3-ylMethyl-aMine hydrochloride:

The characterization of (6-chloro-pyridazin-3-yl)-piperidin-3-ylMethyl-aMine hydrochloride involves various techniques, such as mass spectrometry, nuclear magnetic resonance spectroscopy, and X-ray crystallography.
Mass spectrometry is used to determine the molecular formula and structural features of the compound.
Nuclear magnetic resonance spectroscopy is used to determine the bonding between atoms and the electronic structure of the molecule.
X-