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Introduction:
In the chemical industry, the production process of a compound is a critical aspect that determines the quality and efficiency of the final product.
In this article, we will discuss the production process of (6-Chloro-pyridazin-3-yl)-piperidin-4-ylMethyl-aMine hydrochloride, 98+% C10H16Cl2N4, MW: 263.
17, a commonly used chemical in various industrial applications.
Chemical Structure:
(6-Chloro-pyridazin-3-yl)-piperidin-4-ylMethyl-aMine hydrochloride is a white or almost white, crystalline powder with a molecular formula of C10H16Cl2N4 and a molecular weight of 263.
17.
The compound belongs to the class of piperidines and is characterized by a piperidine nucleus with a substituted chlorine atom at the 6-position.
The chemical structure of the compound is shown below:
Production Process:
The production process of (6-Chloro-pyridazin-3-yl)-piperidin-4-ylMethyl-aMine hydrochloride involves several steps, which are explained below:
- Synthesis of Piperidine:
The synthesis of piperidine is the first step in the production process.
Piperidine is synthesized by the reaction of ammonia and acetaldehyde in the presence of a catalyst, such as hydrochloric acid.
The reaction generates a complex mixture of compounds, which is then subjected to various purification steps to obtain pure piperidine.
- Substitution Reaction:
The next step involves the substitution reaction of piperidine with chlorine to generate 6-chloro-pyridazin-3-yl)-piperidin-4-ylMethyl-aMine.
This reaction is typically carried out in the presence of a solvent, such as dimethylformamide, and a catalyst, such as sodium hydroxide.
The reaction conditions and the specific solvent used can vary depending on the manufacturing process.
- Hydrolysis:
After the substitution reaction is complete, the compound is subjected to hydrolysis, which involves the addition of water to the reaction mixture.
This step is necessary to remove the byproducts and to generate the final product, (6-Chloro-pyridazin-3-yl)-piperidin-4-ylMethyl-aMine hydrochloride.
- Purification:
The final step in the production process is the purification of (6-Chloro-pyridazin-3-yl)-piperidin-4-ylMethyl-aMine hydrochloride.
This is typically accomplished by crystallization, which allows for the separation of the desired compound from any impurities that may be present.
Conclusion:
The production process of (6-Chloro-pyridazin-3-yl)-piperidin-4-ylMethyl-aMine hydrochloride involves several steps, including the synthesis of piperidine, substitution reaction, hydrolysis, and purification.
The specific conditions and steps used can vary depending on the manufacturing process.
However, the process outlined above provides a general overview of the production process of this compound.
The efficient and effective production of this compound is critical for its application in various industrial processes.