The high-quality development plan for the API industry was issued

The "Notice of the National Development and Reform Commission and the Ministry of Industry and Information Technology on the Implementation Plan for Promoting the High-Quality Development of the API Industry" was issued last week
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The "Notice" aims to accelerate the pace of high-quality development of the API industry under the new situation, puts forward new requirements for the green development of the chemical API industry, and clarifies eight major tasks for the development of the API industry
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The "Notice" pointed out that chemical raw materials are the basic raw materials and active ingredients of drugs
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At present, China has become the world's largest producer and exporter of APIs, but at the same time there are problems such as unreasonable industrial structure, imperfect industrial layout, and low level of green production
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The "Notice" emphasizes that it is necessary to adhere to the basic principles of innovation-led, green and low-carbon, scientific layout, and open development.
By 2025, develop a batch of high-value-added and high-growth varieties, break through a batch of green and low-carbon technology and equipment, and cultivate a batch of Leading enterprises with international competitiveness will build a group of industrial clusters and production bases with global influence
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The innovative development and advanced manufacturing level of the API industry has been greatly improved, and the green and low-carbon development capacity has been significantly improved
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The "Notice" clarifies eight major tasks for the development of the API industry
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One is to promote the innovation and upgrading of production technology
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In line with the technological innovation trend of APIs, accelerate the development and application of advanced technologies such as synthetic biotechnology, continuous flow microreaction, continuous crystallization and crystal form control, and use modern technology to transform traditional production processes
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Promote digital and intelligent transformation and upgrading of key enterprises to improve production efficiency and quality control
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Focusing on the key common technologies in the production of APIs, support the development of a number of public service platforms with strong externalities
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The second is to promote the green and low-carbon transformation of the industry
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Strengthen forward-looking research layout and develop green and low-carbon production technologies for APIs
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Promote the green transformation of bulk APIs, and continue to reduce energy consumption and emissions per unit of product
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Strengthen the resource utilization of by-products in the production process of APIs, promote the treatment and transformation of volatile organic compounds (VOCs), and improve the comprehensive treatment level of solid waste, high-salt wastewater and organic waste liquid
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The third is to promote the optimization and adjustment of the industrial structure
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Promote the large-scale and intensive development of API production, encourage advantageous enterprises to become bigger and stronger, and increase industrial concentration
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Strictly implement the "Industrial Structure Adjustment Guidance Catalog" and other policies, strictly implement environmental protection, energy consumption, safety and other standards, and accelerate the elimination of outdated products, technologies and equipment
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The fourth is to promote the concentrated development of industries
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Promote new API projects to enter suitable regions and chemical (pharmaceutical) parks established in compliance, and guide existing API companies to optimize and adjust their layout among regions
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Taking into account factors such as raw materials, markets, and technologies, we will build a world-class industrial cluster and production base in areas with good development foundation, prominent location advantages, and abundant element resources
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The fifth is to promote breakthroughs in major equipment research
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Facing the cutting-edge technology field of API production, guide key enterprises to deploy innovation chains with upstream and downstream of the industrial chain and scientific research institutes, accelerate the development of high-end production equipment such as nucleic acid reactors and special consumables such as high-end membrane materials, break through the bottleneck of industrial development, and improve the industrial chain level of autonomy
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Strengthen the sharing of advanced technologies in petrochemical, chemical, pharmaceutical and other industries, and improve the level of industrial integration and innovation
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In addition, the "Plan" also proposes major tasks such as promoting the division of labor and cooperation in related industries, the construction of an industrial standard system, and high-level open cooperation in the industry
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Five major projects for high-quality development of APIs

This time, together with the implementation plan for promoting the high-quality development of the API industry, the "Major Project for High-Quality Development of APIs" was also released, including advanced manufacturing technology innovation, green and low-carbon technology development, high-end production equipment upgrade, energy-saving and environmental protection equipment upgrade, high The five major projects, including the development of energy-efficient materials, will become major projects to promote the high-quality development of APIs
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In terms of advanced manufacturing technology innovation engineering, it will focus on the development of synthetic biotechnology, biocatalyst (enzyme) screening and preparation, continuous flow microreaction, continuous crystallization and crystal form control, chiral synthesis, solid phase synthesis, efficient separation and purification, and trace impurities in drugs Advanced technologies such as control and process analysis
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In terms of green and low-carbon technology development projects, it will focus on the development of enzyme catalysis, electrochemical reaction, photochemical synthesis and other technologies, precious metal catalyst replacement or reuse technology, toxic and harmful raw material replacement technology, compound medium replacement and other fermentation emission reduction technologies, and advanced wastewater oxidation.
, membrane biological reaction and other treatment technologies, high-concentration refractory wastewater treatment technology, volatile organic waste gas treatment technology, waste liquid and residue recycling, harmless treatment and evaluation technology
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In terms of upgrading high-end production equipment, it will support the development of internationally advanced microchannel reactors, peptide synthesizers, nucleic acid synthesizers, new crystallizers, high airtight isolators, fluidized bed dryers, ultrafine powder jet mills, wet process Grinding homogenizer, membrane separation system, automatic synthesis reactor and other high-end equipment
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In terms of energy-saving and environmental protection equipment upgrading projects, it will develop and apply high-efficiency energy-saving equipment for high-energy-consuming links such as air compression, refrigeration, water production, distillation, fermentation, and "three wastes" treatment, improve the level of thermal recycling, and reduce energy consumption
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Focusing on the application of environmental protection technology, develop new "three wastes" treatment equipment such as continuous solvent recovery, catalytic oxidation, sludge reduction, waste liquid desalination, bacterial residue treatment, and regenerative incineration
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In terms of high-performance consumables development projects, high-end membrane materials and components such as nanofiltration, ultrafiltration, microfiltration, and reverse osmosis will be developed, high-performance sensors such as online carbon dioxide, glucose, ammonia nitrogen, and cyanide probes, diatomite filters, activated carbon filters, New filtration consumables such as precious metal removal filter elements, as well as new chromatographic fillers and resins
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