The French company Stilla Technologies released the development project of the high-throughput digital PCR system Naica HT and the 6-color digital detection system

As a commonly used and effective life science research tool, the digital PCR system has been widely accepted and has begun to enter the clinical market

In addition, the company released a 6-color digital PCR detection system development project to enhance the detection capabilities of the system and seek opportunities for cooperation with the diagnostic field and diagnostic reagent manufacturers

Caroline Charky, Vice President of Commercial Operations of Stilla Company, released the high-throughput digital PCR system Naica HT and the new Opal chip at the SLAS Conference (Laboratory Automation and Screening Conference) in February 2019, which can detect ≥240 samples per day.

Charky said, "The Opal chip uses the same microfluidic technology as the first-generation Naica system to generate droplets inside the

The Naica digital PCR system consists of three parts: The Geode device includes automated droplet generation and PCR amplification steps.

"The Sapphire chip used in the Naica digital PCR system is the first-generation chip, which can run 4 samples, 3 chips each time, and ≥60 samples per day

When Stilla conducted market research, it was found that certain laboratories, especially food testing, applications in the field of oncology, such as companion diagnosis and drug monitoring of oncology patients, and large qPCR laboratories that require digital PCR to verify negative results, have Qualcomm Quantity demand

The Naica HT high-throughput digital PCR system can also perform three-color multiplex reactions.

Compared with the Sapphire chip, the Opal chip has a smaller reaction volume

"In the Opal chip we reduced the reaction volume from 25μL to

Aric Joneja, a senior scientist in the rapid diagnostics department of Abbott Laboratories, is using Stilla’s Naica digital PCR system for product development

In a follow-up interview, Charky pointed out that Stilla's patent is completely different from Bio-Rad

At the same time, Stilla is developing a digital PCR system for six-color detection to perform digital PCR detection of multiple target genes.

As previously reported, the use of three-color digital PCR to detect EGFR mutations was published in 2017, and the use of six-color digital PCR to detect non-small cell lung cancer-related mutations, especially the sensitization and drug resistance of EGFR gene, was published in Oncotarget magazine this month.

"The six-color digital PCR system is currently in the testing phase, and Stilla is expected to be released in 2020 or 2021," Charky said

Since the release of the Naica system in 2016, the company has experienced three years, Charky said, recently received financing from Illumina

Last year, Stilla won a public tender from the 39 hospitals in Paris.
These 39 hospitals will complete the procurement of the Naica system within the next four years
.
To support the rapid development of the company, the company is expanding and will triple the area by the end of this year, Charky said
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Welcome to request detailed technical information of the high-throughput digital PCR system-Naica HT