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On May 21, the winners of the first Chinese Chemical Society Life Chemistry Award were announced
.
Among them, the Life Chemistry Achievement Award of the Chinese Chemical Society was awarded to Zhang Lihe, an academician of the Chinese Academy of Sciences, and the Life Chemistry Youth Innovation Award of the Chinese Chemical Society was awarded to Liu Kai of Tsinghua University and Yi Chengqi of Peking University respectively
.
Zhang Lihe, the winner of the first Chinese Chemical Society Life Chemistry Achievement Award, is a professor at Peking University School of Pharmacy and honorary director of the Academic Committee of the State Key Laboratory of Natural Medicines and Biomimetic Medicines
.
Academician Zhang Lihe has made outstanding achievements in nucleic acid chemistry and nucleic acid-targeted drug research.
He is a pioneer and leader in the discipline of chemical biology in China.
He is mainly engaged in the research of nucleic acid chemistry and anti-tumor and anti-viral drugs
.
He systematically studied the chemical and biological activities and structure-activity relationship of the intracellular messenger molecules cADPR and cAMP and found that 8-chloroadenosine is a new anticancer agent with low toxicity acting on the signal transduction system and can induce differentiation of tumor cells.
;Research on the mechanism of enzymatic nucleic acid cleavage of nucleic acid chains, the properties of artificially modified oligonucleotides and their recognition of nucleic acids, and the antitumor and antiviral activities of various nucleosides, nucleotides and their conjugates made outstanding contributions in the field
.
He also served as the director of the Department of Chemistry of the National Natural Science Foundation of China, the convener of the Pharmacy Discipline of the Academic Degrees Committee of the State Council, the Fellow of the Royal Society of Chemistry, and the Chairman of the Asian Pharmacy Society
.
Liu Kai, winner of the Life Chemistry Youth Innovation Award of the Chinese Chemical Society, is a tenured associate professor, distinguished researcher, and doctoral supervisor of Tsinghua University.
He has worked in Changchun Institute of Applied Chemistry, Chinese Academy of Sciences and Department of Chemistry, Tsinghua University.
Since 2019, he has served as the chief scientist of national key projects.
, mainly engaged in the creation of rare earth biosynthesis systems and high-tech applications
.
Yi Chengqi, another winner of the Life Chemistry Youth Innovation Award of the Chinese Chemical Society, is a Peking University Boya Distinguished Professor and Doctoral Supervisor.
He is currently working in the School of Life Sciences, Peking University
.
Through chemical biology and other means, he developed new technologies for the labeling and detection of nucleic acid modifications, and studied their biological functions, expanding the new field of epitranscriptomics
.
The selection of the first Chinese Chemical Society Life Chemistry Award was launched on January 1, 2022
.
According to the "Chinese Chemical Society Life Chemistry Award Regulations", the final list of winners will be generated after nomination by members of the professional committee, review by the award committee, election by secret ballot, and approval by the Chinese Chemical Society
.
The award is established and run by the Chemical Biology Professional Committee of the Chinese Chemical Society.
The prize is donated and funded by Zhao Yufen, an academician of the Chinese Academy of Sciences
.