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Plastics are beyond the reach of traditional materials in terms of plasticity, durability and chemical stability, so they are widely used in industrial production and life
.
The metabolomics research group led by Cui Qiu, a researcher at the Qingdao Institute of Bioenergy and Processes of the Chinese Academy of Sciences, has successfully established a mature gene manipulation platform for Clostridium thermocellum, a typical thermophilic bacterium.
Arbitrary genetic modification realizes the directional construction of efficient whole-bacteria catalysts
.
Using Clostridium thermocellum as a chassis cell, the researchers heterologously expressed the thermophilic cutinase LCC from the branch and leaf compost metagenome in C.
thermocellum, thereby successfully establishing a thermophilic whole bacteria catalyst with PET degradation function (Fig.
1)
.
This work was funded by the Strategic Pilot Project of the Chinese Academy of Sciences, the National Natural Science Foundation of China, and the Natural Science Foundation of Shandong Province
.