 Home > Biochemistry News > Microbiology News > Rapid Strain Evaluation Using Dynamic DO-Stat Fed-Batch Fermentation Under Scale-Down Conditions

Rapid Strain Evaluation Using Dynamic DO-Stat Fed-Batch Fermentation Under Scale-Down Conditions

 Last Update: 2021-01-31
 Source: Internet
 Author: User

Tags

strain measurement devices

scale systems

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

While large amount of strains can be quickly generated via metabolic engineering, the speed/efficiency of evaluating each strain becomes the bottleneck in the process from strain development to final production. In this chapter, a method is introduced to rapidly evaluate strain performance in fed-batch fermentation mode by using dynamic dissolved oxygen stat feed back control with no additional advanced online measurement. In addition, a scale-down feature is integrated in the method to mimic the limitation of oxygen transfer in large-scale vessels, so that strains can be evaluated under the conditions close to that in large-scale bioreactors. The method has been implemented in several commercial standard benchtop scale fermentation systems with different fermentation control software.

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

Schizophyllan, CAS:9050-67-3

CAS No.: 9050-67-3

Reagent Grade

$55-58/G FOB

alpha-Casozepine CAS 117592-45-7 1mg/5mg/10mg/25mg/50mg/100mg 98% China Factory

CAS No.: 117592-45-7

Pharmacy Grade

$100-120/G FOB

Lactium T29892 CAS 117592-45-7 alpha-Casozepine Manufacturer/Lab Test T29892-25mg-TM

CAS No.: 117592-45-7

Pharmacy Grade

$100-120/G FOB

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.