Protein also has a "dual personality
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Last Update: 2015-08-06
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Source: Internet
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Author: User
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Recently, a new study published in the journal Molecular Cell found that a protein has similar duality, sometimes it can inhibit bad cells, sometimes it can promote the growth of cancer cells Researchers say that in the future, the protein can be used to develop new anticancer drugs by "suppressing evil and promoting good" Researchers from Oxford University and other institutions found that a protein called "E2F" plays an important regulatory role in cell growth, differentiation and death Under normal circumstances, it can monitor DNA damage in cells, and start the cell death process, so that the damaged cells no longer differentiate and proliferate, but gradually apoptosis But in cancer cells, the monitoring function of "E2F" is often out of control, making cancer cells not only not killed, but also crazy growth and spread Further study found that in the monitoring mechanism of "E2F", two enzymes play a key role They will compete with each other to identify the "good" or "bad" of the cell, so as to decide whether to promote the cell growth or guide it to death In the future, researchers say, they hope to use this feature to develop new drugs, so that "E2F" no longer shows the "bad" side, so as to correctly identify and kill cancer cells.
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