Professor Wu Rina of Shenyang Agricultural University: Research Progress in Essential Fatty Acid Biosynthesis and Production

Original Title: Biochem. Eng. J. │Professor Wu Rina of Shenyang Agricultural University: Research Progress in Essential Fatty Acid Biosynthesis and Production: Elucidating the Role of Δ12/Δ15 Fatty Acid Desaturase , Shenyang Key Laboratory of Microbial Fermentation Technology Innovation Wu Chen, Shi Haisu*, Wu Rina*, etc. reviewed the biosynthesis and production of essential fatty acids, elucidated the Δ12/15 fatty acid desaturase (Δ12/15 fatty acid desaturase, FADS12 /15) Role in essential fatty acid biosynthesis . Essential fatty acids provide a variety of biological and physiological benefits, however, they cannot be synthesized in the human body and must be obtained from the diet . Essential fatty acids from traditional sources such as animals and plants are far from meeting human needs, and some new sources of essential fatty acids are currently being explored, including microalgae, oleaginous yeast, and fungi . In these species, FADS12/15 play key roles in essential fatty acid biosynthesis . Under appropriate environmental conditions, the production of essential fatty acids can be enhanced by FADS12/15 catalysis or genetically engineered organisms with high FADS12/15 activity . 　　This paper reviews the recent research progress on new sources of essential fatty acids such as microalgae and oil-producing microorganisms, elucidates the role of FADS12/15 in essential fatty acid biosynthesis and its catalytic mechanism, and further elaborates the environmental conditions and genetically engineered organisms that enhance the production of essential fatty acids. , highlighting key bottlenecks and proposing strategies to improve essential fatty acid production . Finally, the potential prospects of industrial essential fatty acid production in terms of commercial safety, downstream processing and development of microbial cell factories are prospected . 　　The article "Recent advances on essential fatty acid biosynthesis and production: Clarifying the roles of Δ12/Δ15 fatty acid desaturase" was published in Biochemical Engineering Journal in January 2022 . "Dairy Science and Technology" editorial board professor Wu Zina is one of the corresponding authors of this article . Expert introduction Urina, Ph. D. , professor, doctoral supervisor, post-doctoral cooperative supervisor . Research direction: exploration and utilization of probiotic resources, fermented food, intestinal nutrition and health . He is currently the director of Liaoning Provincial Food Fermentation Technology Engineering Research Center, the chief scientist of Shenyang Key Laboratory of Food Fermentation Technology Innovation, and the leader of food fermentation and probiotics research . Presided over 3 projects of the National Natural Science Foundation of China, presided over the key projects of the National Natural Science Foundation of China, the first-class funding project of the China Postdoctoral Science Foundation, the Liaoning Provincial "Xing Liao Talents" Support Program, the Liaoning Provincial Agricultural Field Youth Science and Technology Innovation Talent Project, and the Liaoning Provincial Higher Education Project. More than 20 projects such as the School Excellent Talent Project, the Liaoning Provincial Department of Education Project, the Shenyang Young and Middle-aged Scientific and Technological Innovation Talent Project, and the Shenyang Furun Achievement Transformation Project, participated in the National 863 Major Project, the National "Twelfth Five-Year" Science and Technology Support, and the National Spark Plan. More than 40 projects, such as the National Natural Science Foundation of China . Published more than 150 scientific papers in Molecular and Cellular Proteomics, Food Chemistry, International Journal of Food Microbiology, Food Research International, Journal of Agricultural and Food Chemistry, Food & Function , etc. , of which 82 were included in SCI, with the highest impact factor of 9. 606; EI 23 articles were collected . Applied for 22 national patents, obtained 10 authorized national patents, and obtained 9 authorized national software copyrights . 1 paper was selected for the 2015-2019 "Top Runner 5000 - Top Academic Papers in China's Fine Science and Technology Journals"; 12 textbooks and books, 2 English monographs (Springer), and 1 national standard were formulated . Served as editorial board member of magazines such as "Chinese Journal of Microecology", "Chinese Brewing", "Food Research and Development", "Dairy Science and Technology", Yuyuan Sauerkraut, Qinghua Brewing, Yiyuan, Yurun, Shuanghui Enterprise Consulting Expert, Degree thesis of the Academic Degrees Center of the State Council, National Natural Science Foundation of China, Postdoctoral Fund of the Ministry of Education, Ministry of Science and Technology, Ministry of Education Science and Technology Evaluation and Review, Science and Technology Department of Liaoning Province, Science and Technology Department of Henan Province, Shenyang Science and Technology Project Evaluation Expert, Nature Communication, MCP, Trends in Reviewer for Food Science & Technology, Critical Reviews in Food Science and Nutrition, Food Chemistry, Food Microbiology and other journals . Translator: Liu Dan, Editor in charge: Liu Li   Disclaimer: This article only represents the author's personal opinion and has nothing to do with China Probiotics Network . Its originality and the text and content stated in the text have not been verified by this site, and this site does not make any guarantee or commitment to the authenticity, completeness and timeliness of this text and all or part of its content and text. Readers are only for reference and please Verify the relevant content yourself .   Copyright Notice 1. Some articles reproduced on this site are not original, and their copyright and responsibility belong to the original author . 2. All reprinted articles, links and pictures on this website are for the purpose of conveying more information, and the source and author are clearly indicated. 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　　Original Title: Biochem.
Eng.
J.
│Professor Wu Rina of Shenyang Agricultural University: Research Progress in Essential Fatty Acid Biosynthesis and Production: Elucidating the Role of Δ12/Δ15 Fatty Acid Desaturase , Shenyang Key Laboratory of Microbial Fermentation Technology Innovation Wu Chen, Shi Haisu*, Wu Rina*, etc.
reviewed the biosynthesis and production of essential fatty acids, elucidated the Δ12/15 fatty acid desaturase (Δ12/15 fatty acid desaturase, FADS12 /15) Role in essential fatty acid biosynthesis
.


　　Essential fatty acids provide a variety of biological and physiological benefits, however, they cannot be synthesized in the human body and must be obtained from the diet
.
Essential fatty acids from traditional sources such as animals and plants are far from meeting human needs, and some new sources of essential fatty acids are currently being explored, including microalgae, oleaginous yeast, and fungi
.
In these species, FADS12/15 play key roles in essential fatty acid biosynthesis
.
Under appropriate environmental conditions, the production of essential fatty acids can be enhanced by FADS12/15 catalysis or genetically engineered organisms with high FADS12/15 activity
.


　　This paper reviews the recent research progress on new sources of essential fatty acids such as microalgae and oil-producing microorganisms, elucidates the role of FADS12/15 in essential fatty acid biosynthesis and its catalytic mechanism, and further elaborates the environmental conditions and genetically engineered organisms that enhance the production of essential fatty acids.
, highlighting key bottlenecks and proposing strategies to improve essential fatty acid production
.
Finally, the potential prospects of industrial essential fatty acid production in terms of commercial safety, downstream processing and development of microbial cell factories are prospected
.


　　The article "Recent advances on essential fatty acid biosynthesis and production: Clarifying the roles of Δ12/Δ15 fatty acid desaturase" was published in Biochemical Engineering Journal in January 2022
.
"Dairy Science and Technology" editorial board professor Wu Zina is one of the corresponding authors of this article
.


Expert introduction
Urina, Ph.
D.
, professor, doctoral supervisor, post-doctoral cooperative supervisor
.
Research direction: exploration and utilization of probiotic resources, fermented food, intestinal nutrition and health
.
He is currently the director of Liaoning Provincial Food Fermentation Technology Engineering Research Center, the chief scientist of Shenyang Key Laboratory of Food Fermentation Technology Innovation, and the leader of food fermentation and probiotics research
.


Presided over 3 projects of the National Natural Science Foundation of China, presided over the key projects of the National Natural Science Foundation of China, the first-class funding project of the China Postdoctoral Science Foundation, the Liaoning Provincial "Xing Liao Talents" Support Program, the Liaoning Provincial Agricultural Field Youth Science and Technology Innovation Talent Project, and the Liaoning Provincial Higher Education Project.
More than 20 projects such as the School Excellent Talent Project, the Liaoning Provincial Department of Education Project, the Shenyang Young and Middle-aged Scientific and Technological Innovation Talent Project, and the Shenyang Furun Achievement Transformation Project, participated in the National 863 Major Project, the National "Twelfth Five-Year" Science and Technology Support, and the National Spark Plan.
More than 40 projects, such as the National Natural Science Foundation of China
.
Published more than 150 scientific papers in Molecular and Cellular Proteomics, Food Chemistry, International Journal of Food Microbiology, Food Research International, Journal of Agricultural and Food Chemistry, Food & Function , etc.
, of which 82 were included in SCI, with the highest impact factor of 9.
606; EI 23 articles were collected
.
Applied for 22 national patents, obtained 10 authorized national patents, and obtained 9 authorized national software copyrights
.
1 paper was selected for the 2015-2019 "Top Runner 5000 - Top Academic Papers in China's Fine Science and Technology Journals"; 12 textbooks and books, 2 English monographs (Springer), and 1 national standard were formulated
.


Served as editorial board member of magazines such as "Chinese Journal of Microecology", "Chinese Brewing", "Food Research and Development", "Dairy Science and Technology", Yuyuan Sauerkraut, Qinghua Brewing, Yiyuan, Yurun, Shuanghui Enterprise Consulting Expert, Degree thesis of the Academic Degrees Center of the State Council, National Natural Science Foundation of China, Postdoctoral Fund of the Ministry of Education, Ministry of Science and Technology, Ministry of Education Science and Technology Evaluation and Review, Science and Technology Department of Liaoning Province, Science and Technology Department of Henan Province, Shenyang Science and Technology Project Evaluation Expert, Nature Communication, MCP, Trends in Reviewer for Food Science & Technology, Critical Reviews in Food Science and Nutrition, Food Chemistry, Food Microbiology and other journals
.


Translator: Liu Dan, Editor in charge: Liu Li

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　　Original Title: Biochem.
Eng.
J.
│Professor Wu Rina of Shenyang Agricultural University: Research Progress in Essential Fatty Acid Biosynthesis and Production: Elucidating the Role of Δ12/Δ15 Fatty Acid Desaturase , Shenyang Key Laboratory of Microbial Fermentation Technology Innovation Wu Chen, Shi Haisu*, Wu Rina*, etc.
reviewed the biosynthesis and production of essential fatty acids, elucidated the Δ12/15 fatty acid desaturase (Δ12/15 fatty acid desaturase, FADS12 /15) Role in essential fatty acid biosynthesis
.


　　Essential fatty acids provide a variety of biological and physiological benefits, however, they cannot be synthesized in the human body and must be obtained from the diet
.
Essential fatty acids from traditional sources such as animals and plants are far from meeting human needs, and some new sources of essential fatty acids are currently being explored, including microalgae, oleaginous yeast, and fungi
.
In these species, FADS12/15 play key roles in essential fatty acid biosynthesis
.
Under appropriate environmental conditions, the production of essential fatty acids can be enhanced by FADS12/15 catalysis or genetically engineered organisms with high FADS12/15 activity
.


　　This paper reviews the recent research progress on new sources of essential fatty acids such as microalgae and oil-producing microorganisms, elucidates the role of FADS12/15 in essential fatty acid biosynthesis and its catalytic mechanism, and further elaborates the environmental conditions and genetically engineered organisms that enhance the production of essential fatty acids.
, highlighting key bottlenecks and proposing strategies to improve essential fatty acid production
.
Finally, the potential prospects of industrial essential fatty acid production in terms of commercial safety, downstream processing and development of microbial cell factories are prospected
.


　　The article "Recent advances on essential fatty acid biosynthesis and production: Clarifying the roles of Δ12/Δ15 fatty acid desaturase" was published in Biochemical Engineering Journal in January 2022
.
"Dairy Science and Technology" editorial board professor Wu Zina is one of the corresponding authors of this article
.


Expert introduction
Urina, Ph.
D.
, professor, doctoral supervisor, post-doctoral cooperative supervisor
.
Research direction: exploration and utilization of probiotic resources, fermented food, intestinal nutrition and health
.
He is currently the director of Liaoning Provincial Food Fermentation Technology Engineering Research Center, the chief scientist of Shenyang Key Laboratory of Food Fermentation Technology Innovation, and the leader of food fermentation and probiotics research
.


Presided over 3 projects of the National Natural Science Foundation of China, presided over the key projects of the National Natural Science Foundation of China, the first-class funding project of the China Postdoctoral Science Foundation, the Liaoning Provincial "Xing Liao Talents" Support Program, the Liaoning Provincial Agricultural Field Youth Science and Technology Innovation Talent Project, and the Liaoning Provincial Higher Education Project.
More than 20 projects such as the School Excellent Talent Project, the Liaoning Provincial Department of Education Project, the Shenyang Young and Middle-aged Scientific and Technological Innovation Talent Project, and the Shenyang Furun Achievement Transformation Project, participated in the National 863 Major Project, the National "Twelfth Five-Year" Science and Technology Support, and the National Spark Plan.
More than 40 projects, such as the National Natural Science Foundation of China
.
Published more than 150 scientific papers in Molecular and Cellular Proteomics, Food Chemistry, International Journal of Food Microbiology, Food Research International, Journal of Agricultural and Food Chemistry, Food & Function , etc.
, of which 82 were included in SCI, with the highest impact factor of 9.
606; EI 23 articles were collected
.
Applied for 22 national patents, obtained 10 authorized national patents, and obtained 9 authorized national software copyrights
.
1 paper was selected for the 2015-2019 "Top Runner 5000 - Top Academic Papers in China's Fine Science and Technology Journals"; 12 textbooks and books, 2 English monographs (Springer), and 1 national standard were formulated
.


Served as editorial board member of magazines such as "Chinese Journal of Microecology", "Chinese Brewing", "Food Research and Development", "Dairy Science and Technology", Yuyuan Sauerkraut, Qinghua Brewing, Yiyuan, Yurun, Shuanghui Enterprise Consulting Expert, Degree thesis of the Academic Degrees Center of the State Council, National Natural Science Foundation of China, Postdoctoral Fund of the Ministry of Education, Ministry of Science and Technology, Ministry of Education Science and Technology Evaluation and Review, Science and Technology Department of Liaoning Province, Science and Technology Department of Henan Province, Shenyang Science and Technology Project Evaluation Expert, Nature Communication, MCP, Trends in Reviewer for Food Science & Technology, Critical Reviews in Food Science and Nutrition, Food Chemistry, Food Microbiology and other journals
.


Translator: Liu Dan, Editor in charge: Liu Li

---

　　Original Title: Biochem.
Eng.
J.
│Professor Wu Rina of Shenyang Agricultural University: Research Progress in Essential Fatty Acid Biosynthesis and Production: Elucidating the Role of Δ12/Δ15 Fatty Acid Desaturase , Shenyang Key Laboratory of Microbial Fermentation Technology Innovation Wu Chen, Shi Haisu*, Wu Rina*, etc.
reviewed the biosynthesis and production of essential fatty acids, elucidated the Δ12/15 fatty acid desaturase (Δ12/15 fatty acid desaturase, FADS12 /15) Role in essential fatty acid biosynthesis
.
Original Title: Biochem.
Eng.
J.
│Professor Wu Rina of Shenyang Agricultural University: Research Progress in Essential Fatty Acid Biosynthesis and Production: Elucidating the Role of Δ12/Δ15 Fatty Acid Desaturase

　　Essential fatty acids provide a variety of biological and physiological benefits, however, they cannot be synthesized in the human body and must be obtained from the diet
.
Essential fatty acids from traditional sources such as animals and plants are far from meeting human needs, and some new sources of essential fatty acids are currently being explored, including microalgae, oleaginous yeast, and fungi
.
In these species, FADS12/15 play key roles in essential fatty acid biosynthesis
.
Under appropriate environmental conditions, the production of essential fatty acids can be enhanced by FADS12/15 catalysis or genetically engineered organisms with high FADS12/15 activity
.


　　This paper reviews the recent research progress on new sources of essential fatty acids such as microalgae and oil-producing microorganisms, elucidates the role of FADS12/15 in essential fatty acid biosynthesis and its catalytic mechanism, and further elaborates the environmental conditions and genetically engineered organisms that enhance the production of essential fatty acids.
, highlighting key bottlenecks and proposing strategies to improve essential fatty acid production
.
Finally, the potential prospects of industrial essential fatty acid production in terms of commercial safety, downstream processing and development of microbial cell factories are prospected
.


　　The article "Recent advances on essential fatty acid biosynthesis and production: Clarifying the roles of Δ12/Δ15 fatty acid desaturase" was published in Biochemical Engineering Journal in January 2022
.
"Dairy Science and Technology" editorial board professor Wu Zina is one of the corresponding authors of this article
.


Expert introduction
Urina, Ph.
D.
, professor, doctoral supervisor, post-doctoral cooperative supervisor
.
Research direction: exploration and utilization of probiotic resources, fermented food, intestinal nutrition and health
.
He is currently the director of Liaoning Provincial Food Fermentation Technology Engineering Research Center, the chief scientist of Shenyang Key Laboratory of Food Fermentation Technology Innovation, and the leader of food fermentation and probiotics research
.


Presided over 3 projects of the National Natural Science Foundation of China, presided over the key projects of the National Natural Science Foundation of China, the first-class funding project of the China Postdoctoral Science Foundation, the Liaoning Provincial "Xing Liao Talents" Support Program, the Liaoning Provincial Agricultural Field Youth Science and Technology Innovation Talent Project, and the Liaoning Provincial Higher Education Project.
More than 20 projects such as the School Excellent Talent Project, the Liaoning Provincial Department of Education Project, the Shenyang Young and Middle-aged Scientific and Technological Innovation Talent Project, and the Shenyang Furun Achievement Transformation Project, participated in the National 863 Major Project, the National "Twelfth Five-Year" Science and Technology Support, and the National Spark Plan.
More than 40 projects, such as the National Natural Science Foundation of China
.
Published more than 150 scientific papers in Molecular and Cellular Proteomics, Food Chemistry, International Journal of Food Microbiology, Food Research International, Journal of Agricultural and Food Chemistry, Food & Function , etc.
, of which 82 were included in SCI, with the highest impact factor of 9.
606; EI 23 articles were collected
.
Applied for 22 national patents, obtained 10 authorized national patents, and obtained 9 authorized national software copyrights
.
1 paper was selected for the 2015-2019 "Top Runner 5000 - Top Academic Papers in China's Fine Science and Technology Journals"; 12 textbooks and books, 2 English monographs (Springer), and 1 national standard were formulated
.


Served as editorial board member of magazines such as "Chinese Journal of Microecology", "Chinese Brewing", "Food Research and Development", "Dairy Science and Technology", Yuyuan Sauerkraut, Qinghua Brewing, Yiyuan, Yurun, Shuanghui Enterprise Consulting Expert, Degree thesis of the Academic Degrees Center of the State Council, National Natural Science Foundation of China, Postdoctoral Fund of the Ministry of Education, Ministry of Science and Technology, Ministry of Education Science and Technology Evaluation and Review, Science and Technology Department of Liaoning Province, Science and Technology Department of Henan Province, Shenyang Science and Technology Project Evaluation Expert, Nature Communication, MCP, Trends in Reviewer for Food Science & Technology, Critical Reviews in Food Science and Nutrition, Food Chemistry, Food Microbiology and other journals
.


Translator: Dan Liu, Editor in charge: Li Liu Molecular and Cellular Proteomics, Food Chemistry, International Journal of Food Microbiology, Food Research International, Journal of Agricultural and Food Chemistry, Food & Function Nature Communication, MCP, Trends in Food Science & Technology, Critical Reviews in Food Science and Nutrition, Food Chemistry, Food Microbiology

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