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Preparation of Cell-Wall Fractions from Mycobacteria

 Last Update: 2021-02-21
 Source: Internet
 Author: User

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50 1 mixture

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Research extending over 50 years has implicated various components of the mycobacterial cell-wall matrix in many host responses associated with tuberculosis and other mycobacterioses (
1
). The observed responses originally included granuloma formation, high-titer IgG antibodies, and the state of the T cell-mediated immunological anergy evident in multibacillary leprosy and, more recently, in the induction of specific cytokines, phagocytosis of the organism, cellular refractivity to cytokine stimulation, and regulation of phagosome-lysosome fusion.

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