Nature Reviews: Understanding the role of the microbiota-gut-brain axis in Parkinson's disease

Nature Reviews Neurology [IF:4711] ① Gut-brain axis plays an important role in the occurrence and development of Parkinson's disease (PD); ② Abnormal structure or function of intestinal flora, constipation, altered intestinal permeability and inflammation, α-synuclein in the intestine Aggregation in the nervous system increases the risk of PD; ③ Various intestinal diseases (infection, dysbiosis, inflammation and movement disorders), intestinal intervention and dietary factors are all related to the development and progression of PD; ④ Intestinal motility, levodopa Drug metabolism and intestinal flora have a significant impact on the treatment effect of PD; ⑤ Various intestinal flora-oriented therapies (diet, probiotics, fecal transplantation, postbiotics, e. ) are expected to control or improve PD-related symptoms and sympto. proce. The microbiome–gut–brain axis in Parkinson disease — from basic research to the clinic06-24, doi: 11038/s41582-022-00681-2 [Editor's comment] Parkinson's disease (PD) is a common neurodegenerative disease The occurrence of the disease is affected by many factors such as heredity, environment, infection, aging and oxidative stre. The microbiota-gut-brain axis is a two-way information communication system integrating brain and gut functio. A recent review published in Nature Reviews Neurology outlines the potential roles and interrelationships of the gut-brain axis in PD, including the vagus nerve, alpha-synuclein in the enteric nervous system, altered gut permeability and inflammation, and Gut microbiota and its metabolic activi. It also expounded that gut-related factors are closely related to the development of PD treatment, and also looked forward to various future intestinal flora-oriented therapies for PD, which are worthy of study and exchange by relevant personn. @jiuqingchen   Disclaimer: This article only represents the author's personal opinion and has nothing to do with China Probiotics Netwo. Its originality and the text and content stated in the text have not been verified by this site, and this site does not make any guarantee or commitment to the authenticity, completeness and timeliness of this text and all or part of its content and te. Readers are only for reference and please Verify the relevant content yourse. Copyright Notice Some articles reproduced on this site are not original, and their copyright and responsibility belong to the original auth. All reprinted articles, links and pictures on this website are for the purpose of conveying more information, and the source and author are clearly indicat. Media or individuals who do not wish to be reprinted can contact us for infringing information that can provide sufficient eviden. , bio149 will be deleted within 12 hours after confirmati. Users are welcome to submit original articles to 86371366@. com, which will be published on the homepage after review, and the copyright and responsibility of the articles belong to the send.

Nature Reviews Neurology
① Gut-brain axis plays an important role in the occurrence and development of Parkinson's disease (PD); ② Abnormal structure or function of intestinal flora, constipation, altered intestinal permeability and inflammation, α-synuclein in the intestine Aggregation in the nervous system increases the risk of PD; ③ Various intestinal diseases (infection, dysbiosis, inflammation and movement disorders), intestinal intervention and dietary factors are all related to the development and progression of PD; ④ Intestinal motility, levodopa Drug metabolism and intestinal flora have a significant impact on the treatment effect of PD; ⑤ Various intestinal flora-oriented therapies (diet, probiotics, fecal transplantation, postbiotics, e.

) are expected to control or improve PD-related symptoms and sympto.

proce.

The microbiome–gut–brain axis in Parkinson disease — from basic research to the clinic06-24, doi: 11038/s41582-022-00681-2 [Editor's comment] Parkinson's disease (PD) is a common neurodegenerative disease The occurrence of the disease is affected by many factors such as heredity, environment, infection, aging and oxidative stre.

The microbiota-gut-brain axis is a two-way information communication system integrating brain and gut functio.

A recent review published in Nature Reviews Neurology outlines the potential roles and interrelationships of the gut-brain axis in PD, including the vagus nerve, alpha-synuclein in the enteric nervous system, altered gut permeability and inflammation, and Gut microbiota and its metabolic activi.

It also expounded that gut-related factors are closely related to the development of PD treatment, and also looked forward to various future intestinal flora-oriented therapies for PD, which are worthy of study and exchange by relevant personn.

@jiuqingchen

---

Nature Reviews Neurology
① Gut-brain axis plays an important role in the occurrence and development of Parkinson's disease (PD); ② Abnormal structure or function of intestinal flora, constipation, altered intestinal permeability and inflammation, α-synuclein in the intestine Aggregation in the nervous system increases the risk of PD; ③ Various intestinal diseases (infection, dysbiosis, inflammation and movement disorders), intestinal intervention and dietary factors are all related to the development and progression of PD; ④ Intestinal motility, levodopa Drug metabolism and intestinal flora have a significant impact on the treatment effect of PD; ⑤ Various intestinal flora-oriented therapies (diet, probiotics, fecal transplantation, postbiotics, e.

) are expected to control or improve PD-related symptoms and sympto.

proce.

The microbiome–gut–brain axis in Parkinson disease — from basic research to the clinic06-24, doi: 11038/s41582-022-00681-2 [Editor's comment] Parkinson's disease (PD) is a common neurodegenerative disease The occurrence of the disease is affected by many factors such as heredity, environment, infection, aging and oxidative stre.

The microbiota-gut-brain axis is a two-way information communication system integrating brain and gut functio.

A recent review published in Nature Reviews Neurology outlines the potential roles and interrelationships of the gut-brain axis in PD, including the vagus nerve, alpha-synuclein in the enteric nervous system, altered gut permeability and inflammation, and Gut microbiota and its metabolic activi.

It also expounded that gut-related factors are closely related to the development of PD treatment, and also looked forward to various future intestinal flora-oriented therapies for PD, which are worthy of study and exchange by relevant personn.

@jiuqingchen

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