MedComm | Team of Professor Xuedong Zhou from Sichuan University: Visual analysis of trends and hotspots in global oral microbiome research

The oral microbiome contains many bacteria that directly or indirectly participate in various functions of the human body.
They have a huge impact on human health, disease and outcome by constantly exchanging signals and substances with the human body.

In order to fully understand the current status of oral microbiome research, the team of Professor Zhou Xuedong from the State Key Laboratory of Oral Disease Research published a paper on MedComm issued by Wiley.
The author extracts the literature on the oral microbiome from the number of articles, countries, institutions, and authors.
, Cited journals, keywords and emergent words, using bibliometrics methods, qualitatively and quantitatively, visually analyze and excavate global oral microbiome research trends and hotspots [1].

The corresponding author of this article is Zhou Xuedong, West China Hospital of Stomatology, Sichuan University, and the first authors are Liao Lin and Wu Jinyun, West China Hospital of Stomatology, Sichuan University.

The oral microbiome is not only closely related to the development of oral diseases [2], but also participates in the development of systemic diseases, such as diabetes, cardiovascular diseases, and respiratory diseases [3].

In order to fully understand the current status of oral microbiome research at home and abroad, the author extracted all oral microbiome-related research literature from the Web of Science core collection as of December 31, 2019, and used bibliometrics methods for qualitative and quantitative evaluation.

At the same time, in order to integrate multi-dimensional information, the author also introduced CiteSpace software for more comprehensive and intuitive analysis, and generated images through Python to represent complex intermediate information, including collaborative connection networks and cluster information.

The authors found that the number of literature in the field of oral microbiology has been increasing year by year, especially after the National Institutes of Health announced the Human Microbiome Project (2007), the increase in the number of related literature has accelerated significantly (Figure 1); the author’s collaboration and field research found that different research fields also Gradually cross and deepen integration to jointly promote the development of health care; the United States is the country that publishes the largest number of documents in this field (Figure 1C), and it has the closest cooperation with other countries.
Among them, Harvard University is the research institution that has contributed the most (Figure 1D).
, The Forsyth Institute is an affiliate of Harvard Medical School); and the oral microbiology research team of the State Key Laboratory of Oral Disease Research in China has led the development of this field in China, and has made great achievements in vertical fields and interdisciplinary in recent years.
contribution.

Figure 1 The authors of Analysis of time, subject categories, countries, and institutions studied the co-citing authors and found that FE Dewhirst, SS Socransky and JA Aas had the most cited articles; an analysis of the cited journals revealed that the Journal of Dental Research (JDR) not only has a high impact factor, but also has the most citations, which shows that these authors and JDR have a high influence in oral microbiome research (Figure 2).

Figure 2 Analysis of co-cited authors, journals, and cited journals At the same time, the author analyzed keywords and found that periodontal disease and dental plaque are the current research hotspots.
The keyword co-occurrence knowledge map constructed by CiteSpace is used to further search for emergencies.
The most common keywords, found that caries in young children, squamous cell carcinoma, intestinal microbiome, Helicobacter pylori, etc.
are the latest sudden keywords (Figure 3).
They are the research frontier and are very likely to become the next period.
Research hotspots. Figure 3 The keywords with the strongest citation bursts of articles on oral microbiome publications from 1959 to 2019 In summary, the oral microbiome knowledge map formed by using big data can provide more valuable information and enable us to study and use the oral cavity more accurately Microorganisms can reduce or even eliminate their adverse effects, enhance their beneficial effects and ultimately improve human oral health.

Therefore, the use of data mining, knowledge graphs, and visualization technologies can continuously expand traditional bibliometrics.
Through full data set analysis, it can help scientists and related personnel to more accurately identify research hotspots and development trends in related fields, and accurately locate future developments.
Direction, explore superior teams or institutions in this field, and improve the input and output of scientific research and production in the whole society. References [1] Liao G, Wu J, Peng X, et al.
Visualized analysis of trends and hotspots in global oral microbiome research: A bibliometric study.
MedComm.
2020;1:351–361.
https://doi.
org /10.
1002/mco2.
47[2] Colombo APV, Tanner ACR.
The role of bacterial biofilms in dental caries and periodontal and peri-implant diseases: a historical perspective.
J Den Res.
2019;98(4):373-385.
[3] He J, Li Y, Cao Y, Xue J, Zhou X.
The oral microbiome diversity and its relation to human diseases.
Folia Microbiol.
2015;60(1):69-80.
Cited paper Liao G, Wu J , Peng X, et al.
Visualized analysis of trends and hotspots in global oral microbiome research: A bibliometric study.
MedComm.
2020;1:351–361.
https://doi.
org/10.
1002/mco2.
47 *Chinese translation only For reference, all content is subject to the original English text.