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On December 24, 2022, the Gansu Science and Technology (Patent) Award Conference and the Qiang Science and Technology Action Work Promotion Video and Telephone Conference were held to commend and reward the scientific and technological workers who contributed to the province's scientific and technological progress and economic and social development in 2021, and the achievements of "Development and Application of Polyolefin Resin Technology for Medical Pharmaceutical Packaging Materials" jointly completed by Lanzhou Petrochemical Company, Petrochemical Research Institute Lanzhou Chemical Research Center and Southwest Chemical Sales Company won the first prize of Gansu Province Science and Technology Progress Award
.
High-risk pharmaceutical polyolefin resin is in long-term contact with liquid drugs, which is as important as drugs, directly affecting people's health and even life safety, so drug safety puts forward harsh technical requirements
for polyolefin resin.
China's pharmaceutical polyolefin resin has long been monopolized by foreign companies, and has become the "neck" material
for safe drug use in China.
Before 2011, all domestic polyolefin resins for pharmaceutical packaging materials relied on imports, and the safety evaluation system was blank, so it was urgent to overcome the "stuck neck" technology in this field
.
In order to realize the industrial application of pharmaceutical polyolefin resin, with the strong support of the provincial party committee and the provincial government and the group company, Lanzhou Petrochemical relies on the major polyolefin project to systematically study the key technologies
of "stuck neck" such as narrow distribution ethylene propylene random copolymerization, ultra-high pressure polymerization, and "ultra-pure" polyolefin production.
After more than ten years of concentrating on the whole industrial chain, major technological breakthroughs
have been made.
The narrow distribution ethylene propylene random copolymerization technology was developed, which solved the problem of high precipitate content.
Invented the high-efficiency and low-migration polymer bifunctional polypropylene resin antioxidant system for medicine, which met the requirements of European and American countries, Japan and other countries; Design and develop a new low-temperature initiation system and ultra-high pressure pharmaceutical polyethylene production technology to ensure the stable and continuous operation of the device under ultra-high pressure; The safety evaluation method and standard system of China's pharmaceutical polyolefin resin have been established, which solves the problem of application evaluation and market access of high-risk pharmaceutical polyolefin resin and fills the national gap
.
It is understood that the achievements of "development and application of polyolefin resin technology for medical pharmaceutical packaging materials" have formed 10 authorized invention patents, released 2 group standards, 5 enterprise standards, published 5 core papers, pioneered the establishment of a pharmaceutical polyolefin resin quality management system in line with pharmaceutical production quality management practices in the field of international petrochemicals, built a 100,000-ton large-scale ultra-clean polyolefin resin production base, and realized the large-scale production of high-risk pharmaceutical polypropylene resin and polyethylene resin products.
Realize the application of polyolefin resin in the field of high-risk pharmaceutical packaging materials, break the foreign monopoly, the performance reaches the level of high-end products in Europe and the United States, and the market share exceeds 80%, effectively ensuring the safety of national drugs and achieving significant economic and social benefits
.
At the same time, "medical polypropylene special material RP260" also won the 2020 "Gansu Province Industrial Excellent New Product First Prize" and 2021 Su Province "Most Influential Product Brand" honorary title
.