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Aminodithioester compounds are patented
The amino acid ester dithioformate compound invented by the Xinjiang Institute of Physical and Chemical Technology of the Chinese Academy of Sciences and its preparation method and use have recently obtained a national invention patent
.
Aminodithioformate compounds are not only highly active but also good sulfur-containing ligands
.
Researchers of the institute use amino acids and dichlorothionyl as raw materials to synthesize the intermediate amino acid methyl ester hydrochloride, and react with carbon disulfide and halogenated hydrocarbons in sodium hydroxide and methanol systems to generate amino acid ester dithioformate compounds
.
The reagents used in this method are common and readily available, the reaction conditions are mild, and the experimental steps are simple
.
The amino acid ester dithioformate compounds synthesized by this method have a good inhibitory effect
on hepatitis B virus.
(Zeng Yu)