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    Home > Food News > Enzyme News > Instead of PCR, RPA has become a powerful tool for pathogen detection

    Instead of PCR, RPA has become a powerful tool for pathogen detection

    • Last Update: 2021-08-10
    • Source: Internet
    • Author: User
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    Biocom reports: Recombinase Polymerase Amplification ( RPA ) is known as a nucleic acid detection technology that can replace PCR (developed by the British company TwistDx Inc )


    In a series of articles published this year, RPA technology is widely used in the detection of common pathogenic bacteria such as Mycobacterium tuberculosis, drug-resistant bacteria MRSA , and Salmonella


    Application of RPA in the field of clinical diagnosis

    Clostridium difficile ( C.


    It is estimated that about one-third of the world’s people are latent with tuberculosis ( TB ) pathogens, most of which are dormant in the lungs


    The abuse of antibiotics has led to an increase in drug-resistant bacteria, which has now become a global public health problem


    A study in " Microchimica Acta " in February this year demonstrated an RPA chip that can simultaneously amplify and detect three pathogens , including Neisseria gonorrhoeae , Salmonella enterica and MRSA


    Application of RPA in the field of food safety

    The Shiga toxin-producing Escherichia coli STEC is the most serious food-borne pathogen in the world


    Salmonella is a major food-borne pathogen


    PCR-ELISA is already a mature technology with a wide range of uses


     

    Biological Communication Editor: Ye Yu

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