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Biocom reports: Recombinase Polymerase Amplification ( RPA ) is known as a nucleic acid detection technology that can replace PCR (developed by the British company TwistDx Inc )
In a series of articles published this year, RPA technology is widely used in the detection of common pathogenic bacteria such as Mycobacterium tuberculosis, drug-resistant bacteria MRSA , and Salmonella
Application of RPA in the field of clinical diagnosis
Clostridium difficile ( C.
It is estimated that about one-third of the world’s people are latent with tuberculosis ( TB ) pathogens, most of which are dormant in the lungs
The abuse of antibiotics has led to an increase in drug-resistant bacteria, which has now become a global public health problem
A study in " Microchimica Acta " in February this year demonstrated an RPA chip that can simultaneously amplify and detect three pathogens , including Neisseria gonorrhoeae , Salmonella enterica and MRSA
Application of RPA in the field of food safety
The Shiga toxin-producing Escherichia coli STEC is the most serious food-borne pathogen in the world
Salmonella is a major food-borne pathogen
PCR-ELISA is already a mature technology with a wide range of uses
Biological Communication Editor: Ye Yu