-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
The intestinal microbiota is a postnatally acquired organ that is composed of a large diversity of bacterial genera and species and has an influence on the physiology of the host, both locally at the intestine and systemically. They perform important functions for the host and can, in turn, be modulated by environmental factors such as nutrition. Specific components of the intestinal microflora, including
Lactobacilli
and
Bifidobacteria
, have been associated with beneficial effects on the host, such as promotion of gut maturation and integrity, antagonisms against pathogens, and immune modulation. Beyond this, the microflora seems to play a significant role in the maintenance of intestinal immune homeostasis and prevention of inflammation. To date, the contribution of the intestinal epithelial cell in the first-line defense against pathogenic bacteria and microbial antigens has been recognized. However, the interactions of intestinal epithelial cells with commensal bacteria are less understood. This chapter intends to summarize some methods that can be used to understand the cellular and molecular mechanisms underlying bacterial modulation of the innate immune response of the host and their contribution to the homeostasis of the immune function.
