In-depth inventory!

The so-called "physical and mental health" refers to ensuring both physical and mental health! Nowadays, with the increasing pressure of people's lives, mental health problems have become more and more prominent, including high pressure, which can easily lead to anxiety, mania, and even depression in severe cases. Other effective treatment methods, and long-term treatment with psychotropic drugs are particularly serious for physical damage . Scientific research has shown that probiotics, as important probiotics, can regulate emotional problems in the field of human mental health through the "gut-brain axis" while regulating the intestinal flora . The research of probiotics for mental health is at the international leading level, and a series of population/clinical trials have been carried out to confirm that probiotics can relieve stress and anxiety and improve the mental health of specific groups . Lactobacillus plantarum P-8 relieves stress and anxiety. As early as 2019, the research and development staff of Ketuo Biosciences published a literature on Lactobacillus plantarum P-8 to relieve stress and anxiety in "Clinical Nutrition"; and in 2021 in "Neurobiology of The relevant mechanism of action of Lactobacillus plantarum P-8 on mental health improvement was republished in Stress . The study found that the administration of probiotic Lactobacillus plantarum P-8 could improve plasma cortisol, INF-ϒ, TNF-ɑ and other cytokine levels, reduce stress and anxiety-related scores, and found that Lactobacillus plantarum P-8 could improve 43 Different metabolic pathways can be used to relieve stress and anxiety . Further research on its mechanism of action found that Lactobacillus plantarum P-8 can stimulate the secretion of neurotransmitters or related substances by regulating the intestinal flora, and increase the synthesis of vitamin K2, γ-aminobutyric acid (GABA), and short-chain fatty acids (SCFAs). Metabolism; direct and indirect regulation of the "gut-brain axis" via the vagus nerve, cytokines and metabolites of microbial origin, thereby relieving stress and anxiety in adults . 　　Relief of stress and anxiety of ocean-going sailors 　　After discovering that Lactobacillus plantarum P-8 relieves stress and anxiety of human body, the research and development team of Ketuo Bio has not stopped exploring the field of mental health, and developed a compound probiotic preparation for ocean-going sailors. A long-term follow-up population trial has been carried out in people who are very prone to emotional health problems, and good research results have been achieved, and it has been successfully published in the international authoritative journal "Gut Microbes" in 2020 . 　　The study found that compound probiotic preparations can well regulate the intestinal flora of voyage crew members and maintain the diversity of intestinal microbes; stabilize the abundance of functional genes of related metabolic pathways, reduce the risk of disease, and relieve the stress and anxiety of voyage crew members. emotions . 　　Ketuo Bio also pays attention to the field of mental health. . . 　　In the process of continuous research on the ocean sailing population, Ketuo Bio also found that the crew members commonly suffer from abnormal defecation frequency, insomnia, poor sleep quality, nausea and overeating. This is an obvious symptom of sub-health state, collectively referred to as "Navigation Syndrome", which is a general term for problems with both physical and mental health of crew members . The study also found a correlation between "Navigation Syndrome" and the structure of the gut microbiota . The improvement of physical health and mental health (related to sleep) is closely related. The improvement of mental health problems is also based on the improvement of intestinal flora and physical health, and the development of sub-health status for specific groups of people for the future. The improved probiotic formula provides scientific support, and the results of this study have been successfully published in Microbiol Spectrum in 2022 . 　　In addition, the research on the adjuvant therapy of Bifidobacterium lactis Probio-M8, the star strain of Ketuo Bio, for autism, Alzheimer's disease and Parkinson's disease, has been carried out in Shenzhen Hospital of Southern Medical University, Affiliated Hospital of Inner Mongolia Medical University and Weihai Municipal Hospital Relevant clinical trials were carried out . In the future, the research of Ketuo Bio probiotics in the field of mental health will continue, and there will be more new discoveries to share with you in the future . 　　Ketuo Bio has always adhered to scientific research and continuous innovation, and cooperated with many domestic universities, research institutes and enterprises to isolate, identify and preserve 21,268 strains of lactic acid bacteria from naturally fermented foods, healthy people's intestines and breast milk from all over Asia. The largest resource bank of lactic acid bacteria strains . A total of 60 clinical trials have been carried out in cooperation with more than ten tertiary hospitals in China, and the effect is remarkable . In the future, Ketuo Bio will continue to innovate and help the healthy development of China's probiotics industry! references: 1. Lee-Ching Lew, Yan-Yan Hor, Nur Asmaa' A. Yusoff, Sy-Bing Choi, Muhamad SB Yusoff, Nurhanis S. Roslan, Anisa Ahmad, Jamilah AM Mohammad, Mohammad Farris IL Abdullah, Norzila Zakaria, Normala Wahid , Zhihong Sun, Lai-Yu Kwok, Heping Zhang, Min-Tze Liong. Probiotic Lactobacillus plantarum P8 alleviated stress and anxiety while enhancing memory and cognition in stressed adults: A randomised, double-blind, placebo-controlled study. Clinical Nutrition 38 ( 2019) 2053-2064 2. Teng Ma, Hao Jin, Lai-Yu Kwok, Zhihong Sun, Min-Tze Liong, Heping Zhang. Probiotic consumption relieved human stress and anxiety symptoms possibly via modulating the neuroactive potential of the gut microbiota. Neurobiology of Stress 14 (2021) 100294 3. Jiachao Zhang, Jinshan Zhao, Hao Jin, Ruirui Lv, Huiwen Shi, Guozhong De, Bo Yang, Zhihong Sun & Heping Zhang (2020): Probiotics maintain the intestinal microbiome homeostasis of the sailors during a long sea voyage, Gut Microbes, DOI: 10. 1080/19490976. 2020. 1722054 4. Zheng Sun, Meng Zhang, Min Li, Yogendra Bhaskar, Jinshan Zhao, Youran Ji, Hongbing Cui, Heping Zhang, Zhihong Sun. Interactions between Human Gut Microbiome Dynamics and Sub-Optimal Health Symptoms during Seafaring Expeditions. Microbiology Spectrum (2022) e00925-21   Disclaimer: This article only represents the author's personal opinion and has nothing to do with China Probiotics Network . Its originality and the text and content stated in the text have not been verified by this site, and this site does not make any guarantee or commitment to the authenticity, completeness and timeliness of this text and all or part of its content and text. Readers are only for reference and please Verify the relevant content yourself .   Copyright Notice 1. Some articles reproduced on this site are not original, and their copyright and responsibility belong to the original author . 2. 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　　The so-called "physical and mental health" refers to ensuring both physical and mental health! Nowadays, with the increasing pressure of people's lives, mental health problems have become more and more prominent, including high pressure, which can easily lead to anxiety, mania, and even depression in severe cases.
Other effective treatment methods, and long-term treatment with psychotropic drugs are particularly serious for physical damage
.
Scientific research has shown that probiotics, as important probiotics, can regulate emotional problems in the field of human mental health through the "gut-brain axis" while regulating the intestinal flora
.
The research of probiotics for mental health is at the international leading level, and a series of population/clinical trials have been carried out to confirm that probiotics can relieve stress and anxiety and improve the mental health of specific groups
.


　　Lactobacillus plantarum P-8 relieves stress and anxiety.



　　As early as 2019, the research and development staff of Ketuo Biosciences published a literature on Lactobacillus plantarum P-8 to relieve stress and anxiety in "Clinical Nutrition"; and in 2021 in "Neurobiology of The relevant mechanism of action of Lactobacillus plantarum P-8 on mental health improvement was republished in Stress
.


　　The study found that the administration of probiotic Lactobacillus plantarum P-8 could improve plasma cortisol, INF-ϒ, TNF-ɑ and other cytokine levels, reduce stress and anxiety-related scores, and found that Lactobacillus plantarum P-8 could improve 43 Different metabolic pathways can be used to relieve stress and anxiety
.
Further research on its mechanism of action found that Lactobacillus plantarum P-8 can stimulate the secretion of neurotransmitters or related substances by regulating the intestinal flora, and increase the synthesis of vitamin K2, γ-aminobutyric acid (GABA), and short-chain fatty acids (SCFAs).
Metabolism; direct and indirect regulation of the "gut-brain axis" via the vagus nerve, cytokines and metabolites of microbial origin, thereby relieving stress and anxiety in adults
.


　　Relief of stress and anxiety of ocean-going sailors


　　After discovering that Lactobacillus plantarum P-8 relieves stress and anxiety of human body, the research and development team of Ketuo Bio has not stopped exploring the field of mental health, and developed a compound probiotic preparation for ocean-going sailors.
A long-term follow-up population trial has been carried out in people who are very prone to emotional health problems, and good research results have been achieved, and it has been successfully published in the international authoritative journal "Gut Microbes" in 2020
.


　　The study found that compound probiotic preparations can well regulate the intestinal flora of voyage crew members and maintain the diversity of intestinal microbes; stabilize the abundance of functional genes of related metabolic pathways, reduce the risk of disease, and relieve the stress and anxiety of voyage crew members.
emotions
.


　　Ketuo Bio also pays attention to the field of mental health.
.
.


　　In the process of continuous research on the ocean sailing population, Ketuo Bio also found that the crew members commonly suffer from abnormal defecation frequency, insomnia, poor sleep quality, nausea and overeating.
This is an obvious symptom of sub-health state, collectively referred to as "Navigation Syndrome", which is a general term for problems with both physical and mental health of crew members
.
The study also found a correlation between "Navigation Syndrome" and the structure of the gut microbiota
.
The improvement of physical health and mental health (related to sleep) is closely related.
The improvement of mental health problems is also based on the improvement of intestinal flora and physical health, and the development of sub-health status for specific groups of people for the future.
The improved probiotic formula provides scientific support, and the results of this study have been successfully published in Microbiol Spectrum in 2022
.


　　In addition, the research on the adjuvant therapy of Bifidobacterium lactis Probio-M8, the star strain of Ketuo Bio, for autism, Alzheimer's disease and Parkinson's disease, has been carried out in Shenzhen Hospital of Southern Medical University, Affiliated Hospital of Inner Mongolia Medical University and Weihai Municipal Hospital Relevant clinical trials were carried out
.
In the future, the research of Ketuo Bio probiotics in the field of mental health will continue, and there will be more new discoveries to share with you in the future
.


　　Ketuo Bio has always adhered to scientific research and continuous innovation, and cooperated with many domestic universities, research institutes and enterprises to isolate, identify and preserve 21,268 strains of lactic acid bacteria from naturally fermented foods, healthy people's intestines and breast milk from all over Asia.
The largest resource bank of lactic acid bacteria strains
.
A total of 60 clinical trials have been carried out in cooperation with more than ten tertiary hospitals in China, and the effect is remarkable
.
In the future, Ketuo Bio will continue to innovate and help the healthy development of China's probiotics industry!

references:

1.
Lee-Ching Lew, Yan-Yan Hor, Nur Asmaa' A.
Yusoff, Sy-Bing Choi, Muhamad SB Yusoff, Nurhanis S.
Roslan, Anisa Ahmad, Jamilah AM Mohammad, Mohammad Farris IL Abdullah, Norzila Zakaria, Normala Wahid , Zhihong Sun, Lai-Yu Kwok, Heping Zhang, Min-Tze Liong.
Probiotic Lactobacillus plantarum P8 alleviated stress and anxiety while enhancing memory and cognition in stressed adults: A randomised, double-blind, placebo-controlled study.
Clinical Nutrition 38 ( 2019) 2053-2064

2.
Teng Ma, Hao Jin, Lai-Yu Kwok, Zhihong Sun, Min-Tze Liong, Heping Zhang.
Probiotic consumption relieved human stress and anxiety symptoms possibly via modulating the neuroactive potential of the gut microbiota.
Neurobiology of Stress 14 (2021) 100294

3.
Jiachao Zhang, Jinshan Zhao, Hao Jin, Ruirui Lv, Huiwen Shi, Guozhong De, Bo Yang, Zhihong Sun & Heping Zhang (2020): Probiotics maintain the intestinal microbiome homeostasis of the sailors during a long sea voyage, Gut Microbes, DOI: 10.
1080/19490976.
2020.
1722054

4.
Zheng Sun, Meng Zhang, Min Li, Yogendra Bhaskar, Jinshan Zhao, Youran Ji, Hongbing Cui, Heping Zhang, Zhihong Sun.
Interactions between Human Gut Microbiome Dynamics and Sub-Optimal Health Symptoms during Seafaring Expeditions.
Microbiology Spectrum (2022) e00925-21

---

　　The so-called "physical and mental health" refers to ensuring both physical and mental health! Nowadays, with the increasing pressure of people's lives, mental health problems have become more and more prominent, including high pressure, which can easily lead to anxiety, mania, and even depression in severe cases.
Other effective treatment methods, and long-term treatment with psychotropic drugs are particularly serious for physical damage
.
Scientific research has shown that probiotics, as important probiotics, can regulate emotional problems in the field of human mental health through the "gut-brain axis" while regulating the intestinal flora
.
The research of probiotics for mental health is at the international leading level, and a series of population/clinical trials have been carried out to confirm that probiotics can relieve stress and anxiety and improve the mental health of specific groups
.


　　Lactobacillus plantarum P-8 relieves stress and anxiety.



　　As early as 2019, the research and development staff of Ketuo Biosciences published a literature on Lactobacillus plantarum P-8 to relieve stress and anxiety in "Clinical Nutrition"; and in 2021 in "Neurobiology of The relevant mechanism of action of Lactobacillus plantarum P-8 on mental health improvement was republished in Stress
.


　　The study found that the administration of probiotic Lactobacillus plantarum P-8 could improve plasma cortisol, INF-ϒ, TNF-ɑ and other cytokine levels, reduce stress and anxiety-related scores, and found that Lactobacillus plantarum P-8 could improve 43 Different metabolic pathways can be used to relieve stress and anxiety
.
Further research on its mechanism of action found that Lactobacillus plantarum P-8 can stimulate the secretion of neurotransmitters or related substances by regulating the intestinal flora, and increase the synthesis of vitamin K2, γ-aminobutyric acid (GABA), and short-chain fatty acids (SCFAs).
Metabolism; direct and indirect regulation of the "gut-brain axis" via the vagus nerve, cytokines and metabolites of microbial origin, thereby relieving stress and anxiety in adults
.


　　Relief of stress and anxiety of ocean-going sailors


　　After discovering that Lactobacillus plantarum P-8 relieves stress and anxiety of human body, the research and development team of Ketuo Bio has not stopped exploring the field of mental health, and developed a compound probiotic preparation for ocean-going sailors.
A long-term follow-up population trial has been carried out in people who are very prone to emotional health problems, and good research results have been achieved, and it has been successfully published in the international authoritative journal "Gut Microbes" in 2020
.


　　The study found that compound probiotic preparations can well regulate the intestinal flora of voyage crew members and maintain the diversity of intestinal microbes; stabilize the abundance of functional genes of related metabolic pathways, reduce the risk of disease, and relieve the stress and anxiety of voyage crew members.
emotions
.


　　Ketuo Bio also pays attention to the field of mental health.
.
.


　　In the process of continuous research on the ocean sailing population, Ketuo Bio also found that the crew members commonly suffer from abnormal defecation frequency, insomnia, poor sleep quality, nausea and overeating.
This is an obvious symptom of sub-health state, collectively referred to as "Navigation Syndrome", which is a general term for problems with both physical and mental health of crew members
.
The study also found a correlation between "Navigation Syndrome" and the structure of the gut microbiota
.
The improvement of physical health and mental health (related to sleep) is closely related.
The improvement of mental health problems is also based on the improvement of intestinal flora and physical health, and the development of sub-health status for specific groups of people for the future.
The improved probiotic formula provides scientific support, and the results of this study have been successfully published in Microbiol Spectrum in 2022
.


　　In addition, the research on the adjuvant therapy of Bifidobacterium lactis Probio-M8, the star strain of Ketuo Bio, for autism, Alzheimer's disease and Parkinson's disease, has been carried out in Shenzhen Hospital of Southern Medical University, Affiliated Hospital of Inner Mongolia Medical University and Weihai Municipal Hospital Relevant clinical trials were carried out
.
In the future, the research of Ketuo Bio probiotics in the field of mental health will continue, and there will be more new discoveries to share with you in the future
.


　　Ketuo Bio has always adhered to scientific research and continuous innovation, and cooperated with many domestic universities, research institutes and enterprises to isolate, identify and preserve 21,268 strains of lactic acid bacteria from naturally fermented foods, healthy people's intestines and breast milk from all over Asia.
The largest resource bank of lactic acid bacteria strains
.
A total of 60 clinical trials have been carried out in cooperation with more than ten tertiary hospitals in China, and the effect is remarkable
.
In the future, Ketuo Bio will continue to innovate and help the healthy development of China's probiotics industry!

references:

1.
Lee-Ching Lew, Yan-Yan Hor, Nur Asmaa' A.
Yusoff, Sy-Bing Choi, Muhamad SB Yusoff, Nurhanis S.
Roslan, Anisa Ahmad, Jamilah AM Mohammad, Mohammad Farris IL Abdullah, Norzila Zakaria, Normala Wahid , Zhihong Sun, Lai-Yu Kwok, Heping Zhang, Min-Tze Liong.
Probiotic Lactobacillus plantarum P8 alleviated stress and anxiety while enhancing memory and cognition in stressed adults: A randomised, double-blind, placebo-controlled study.
Clinical Nutrition 38 ( 2019) 2053-2064

2.
Teng Ma, Hao Jin, Lai-Yu Kwok, Zhihong Sun, Min-Tze Liong, Heping Zhang.
Probiotic consumption relieved human stress and anxiety symptoms possibly via modulating the neuroactive potential of the gut microbiota.
Neurobiology of Stress 14 (2021) 100294

3.
Jiachao Zhang, Jinshan Zhao, Hao Jin, Ruirui Lv, Huiwen Shi, Guozhong De, Bo Yang, Zhihong Sun & Heping Zhang (2020): Probiotics maintain the intestinal microbiome homeostasis of the sailors during a long sea voyage, Gut Microbes, DOI: 10.
1080/19490976.
2020.
1722054

4.
Zheng Sun, Meng Zhang, Min Li, Yogendra Bhaskar, Jinshan Zhao, Youran Ji, Hongbing Cui, Heping Zhang, Zhihong Sun.
Interactions between Human Gut Microbiome Dynamics and Sub-Optimal Health Symptoms during Seafaring Expeditions.
Microbiology Spectrum (2022) e00925-21

---

　　The so-called "physical and mental health" refers to ensuring both physical and mental health! Nowadays, with the increasing pressure of people's lives, mental health problems have become more and more prominent, including high pressure, which can easily lead to anxiety, mania, and even depression in severe cases.
Other effective treatment methods, and long-term treatment with psychotropic drugs are particularly serious for physical damage
.
Scientific research has shown that probiotics, as important probiotics, can regulate emotional problems in the field of human mental health through the "gut-brain axis" while regulating the intestinal flora
.
The research of probiotics for mental health is at the international leading level, and a series of population/clinical trials have been carried out to confirm that probiotics can relieve stress and anxiety and improve the mental health of specific groups
.


　　Lactobacillus plantarum P-8 relieves stress and anxiety.



　　As early as 2019, the research and development staff of Ketuo Biosciences published a literature on Lactobacillus plantarum P-8 to relieve stress and anxiety in "Clinical Nutrition"; and in 2021 in "Neurobiology of The relevant mechanism of action of Lactobacillus plantarum P-8 on mental health improvement was republished in Stress
.


　　The study found that the administration of probiotic Lactobacillus plantarum P-8 could improve plasma cortisol, INF-ϒ, TNF-ɑ and other cytokine levels, reduce stress and anxiety-related scores, and found that Lactobacillus plantarum P-8 could improve 43 Different metabolic pathways can be used to relieve stress and anxiety
.
Further research on its mechanism of action found that Lactobacillus plantarum P-8 can stimulate the secretion of neurotransmitters or related substances by regulating the intestinal flora, and increase the synthesis of vitamin K2, γ-aminobutyric acid (GABA), and short-chain fatty acids (SCFAs).
Metabolism; direct and indirect regulation of the "gut-brain axis" via the vagus nerve, cytokines and metabolites of microbial origin, thereby relieving stress and anxiety in adults
.


　　Relief of stress and anxiety of ocean-going sailors


　　After discovering that Lactobacillus plantarum P-8 relieves stress and anxiety of human body, the research and development team of Ketuo Bio has not stopped exploring the field of mental health, and developed a compound probiotic preparation for ocean-going sailors.
A long-term follow-up population trial has been carried out in people who are very prone to emotional health problems, and good research results have been achieved, and it has been successfully published in the international authoritative journal "Gut Microbes" in 2020
.


　　The study found that compound probiotic preparations can well regulate the intestinal flora of voyage crew members and maintain the diversity of intestinal microbes; stabilize the abundance of functional genes of related metabolic pathways, reduce the risk of disease, and relieve the stress and anxiety of voyage crew members.
emotions
.


　　Ketuo Bio also pays attention to the field of mental health.
.
.


　　In the process of continuous research on the ocean sailing population, Ketuo Bio also found that the crew members commonly suffer from abnormal defecation frequency, insomnia, poor sleep quality, nausea and overeating.
This is an obvious symptom of sub-health state, collectively referred to as "Navigation Syndrome", which is a general term for problems with both physical and mental health of crew members
.
The study also found a correlation between "Navigation Syndrome" and the structure of the gut microbiota
.
The improvement of physical health and mental health (related to sleep) is closely related.
The improvement of mental health problems is also based on the improvement of intestinal flora and physical health, and the development of sub-health status for specific groups of people for the future.
The improved probiotic formula provides scientific support, and the results of this study have been successfully published in Microbiol Spectrum in 2022
.


　　In addition, the research on the adjuvant therapy of Bifidobacterium lactis Probio-M8, the star strain of Ketuo Bio, for autism, Alzheimer's disease and Parkinson's disease, has been carried out in Shenzhen Hospital of Southern Medical University, Affiliated Hospital of Inner Mongolia Medical University and Weihai Municipal Hospital Relevant clinical trials were carried out
.
In the future, the research of Ketuo Bio probiotics in the field of mental health will continue, and there will be more new discoveries to share with you in the future
.


　　Ketuo Bio has always adhered to scientific research and continuous innovation, and cooperated with many domestic universities, research institutes and enterprises to isolate, identify and preserve 21,268 strains of lactic acid bacteria from naturally fermented foods, healthy people's intestines and breast milk from all over Asia.
The largest resource bank of lactic acid bacteria strains
.
A total of 60 clinical trials have been carried out in cooperation with more than ten tertiary hospitals in China, and the effect is remarkable
.
In the future, Ketuo Bio will continue to innovate and help the healthy development of China's probiotics industry!

references:

1.
Lee-Ching Lew, Yan-Yan Hor, Nur Asmaa' A.
Yusoff, Sy-Bing Choi, Muhamad SB Yusoff, Nurhanis S.
Roslan, Anisa Ahmad, Jamilah AM Mohammad, Mohammad Farris IL Abdullah, Norzila Zakaria, Normala Wahid , Zhihong Sun, Lai-Yu Kwok, Heping Zhang, Min-Tze Liong.
Probiotic Lactobacillus plantarum P8 alleviated stress and anxiety while enhancing memory and cognition in stressed adults: A randomised, double-blind, placebo-controlled study.
Clinical Nutrition 38 ( 2019) 2053-2064

2.
Teng Ma, Hao Jin, Lai-Yu Kwok, Zhihong Sun, Min-Tze Liong, Heping Zhang.
Probiotic consumption relieved human stress and anxiety symptoms possibly via modulating the neuroactive potential of the gut microbiota.
Neurobiology of Stress 14 (2021) 100294

3.
Jiachao Zhang, Jinshan Zhao, Hao Jin, Ruirui Lv, Huiwen Shi, Guozhong De, Bo Yang, Zhihong Sun & Heping Zhang (2020): Probiotics maintain the intestinal microbiome homeostasis of the sailors during a long sea voyage, Gut Microbes, DOI: 10.
1080/19490976.
2020.
1722054

4.
Zheng Sun, Meng Zhang, Min Li, Yogendra Bhaskar, Jinshan Zhao, Youran Ji, Hongbing Cui, Heping Zhang, Zhihong Sun.
Interactions between Human Gut Microbiome Dynamics and Sub-Optimal Health Symptoms during Seafaring Expeditions.
Microbiology Spectrum (2022) e00925-21

---