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Efficient production method of vitamin E further reduces costs

 Last Update: 2022-09-03
 Source: Internet
 Author: User

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News from this newspaper, researchers from the Key Laboratory of Biomass Chemical Engineering, Ministry of Education, School of Chemical Engineering and Bioengineering, Zhejiang University recently released a method for high-density production of vitamin E tocotrienols using Saccharomyces cerevisiae

Vitamin E is an essential nutrient in the human diet, with functions such as scavenging free radicals and anti-aging

In order to make tocotrienols more accessible, the researchers referred to the synthesis pathway of vitamin E in photosynthetic organisms, and appropriately truncated the transit peptide from plant-derived enzymes to improve protein expression, and combined with the endogenous shikimate pathway of Saccharomyces cerevisiae and mevalonate pathway, constructed an engineered strain of Saccharomyces cerevisiae producing vitamin

Assays showed that the engineered yeast could produce up to 7.

This method reveals the potential of microbial fermentation to produce vitamin E through the high-density fermentation principle of engineered yeast, which makes vitamin E more efficient and convenient to produce and further reduces the cost of industrial production of vitamin

(Source: China Biotechnology Network)

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