 Home > Biochemistry News > Microbiology News > Detection of SV40 DNA Sequences in Human Tissue

Detection of SV40 DNA Sequences in Human Tissue

 Last Update: 2021-02-16
 Source: Internet
 Author: User

Tags

2 3 dichlorobutane

1 8 3 4

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

Several recent investigations using polymerase chain reaction (
PCR
) detection methods have identified SV40-like
DNA
sequences in human neoplasms, particularly choroid plexus tumors (
1
), ependymomas (
1
), mesotheliomas (
2
), and osteosarcomas (
3
,
4
). Difficulties have arisen because of the use of paraffin-fixed tissue, loss of possible viral episomes during DNA isolation, low copy numbers of viral DNA, PCR contamination, and confusion with BKV and JCV sequences. Nonetheless, the authentication of amplified products by DNA sequencing, the finding of a single 72-bp viral-enhancer repeat element, variability of large tumor antigen (T-ag) carboxy terminal DNA sequences in many specimens, and the isolation of SV40 virus from a choroid plexus tumor all support the validity of the basic observation that SV40 is present in humans, and may therefore contribute to oncogenesis in special situations.

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

Schizophyllan, CAS:9050-67-3

CAS No.: 9050-67-3

Reagent Grade

$55-58/G FOB

alpha-Casozepine CAS 117592-45-7 1mg/5mg/10mg/25mg/50mg/100mg 98% China Factory

CAS No.: 117592-45-7

Pharmacy Grade

$100-120/G FOB

Lactium T29892 CAS 117592-45-7 alpha-Casozepine Manufacturer/Lab Test T29892-25mg-TM

CAS No.: 117592-45-7

Pharmacy Grade

$100-120/G FOB

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.