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    Home > Biochemistry News > Microbiology News > Design and Construction of Poliovirus Epitope Expression Vectors

    Design and Construction of Poliovirus Epitope Expression Vectors

    • Last Update: 2021-02-22
    • Source: Internet
    • Author: User
    Tags

    1 3 bisphosphoglycerate

    application
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    We have developed the very safe and efficacious live-attenuated Sabin 1 poliovirus vaccine strain as a vehicle for the presentation of defined epitopes from foreign pathogens (
    1
    –
    3
    ). Precise modification of the poliovirus capsid is made possible by the application of recombinant
    DNA
    technology to cloned
    cDNA
    copies of the viral genome, which are infectious for mammalian cells in culture (
    4
    ).
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