Decolorizing and whitening drugs

July 27, 2013 classification: efficacy effect: 0 people commented that human skin pigment can produce different kinds of skin color according to different human species, which is mainly caused by four kinds of biological pigments, namely: melanin, carotene, hemoglobin oxide and hemoglobin reduction, in which melanin plays a major role Melanin is produced by melanocytes Mature melanocytes are located in the basal layer of epidermis, which transport melanin particles to keratinocytes of epidermis And with the periodic renewal of the cuticle, some of the melanin in the dermis is phagocytized and degraded by phagocytes, or enters the blood circulation through the lymph nodes, and finally is discharged from the urine The biochemical synthesis mechanism of melanin has not been fully understood Generally, melanin is formed through the following reactions (1) increase of melanin (1) melanocyte stimulating hormone [MSH] secreted by pituitary gland (2) estrogen secreted by gonad (pregnancy, contraceptive and endocrine disorders) (3) Thyroxine (hyperthyroidism) secreted by the thyroid gland (4) UV irradiation can activate the activity of tyrosine (5) The activity of thiohydrol [- SH] decreased, the activity of tyrosinase increased and the activity of copper ion released Such as: local skin inflammation, grinding, skin replacement, heavy metals (iron, silver, arsenic, mercury, etc.) (6) The increase of lipid peroxide, chronic malnutrition and poor blood flow can make the source of thiohydrogen insufficient (such as: cysteine, methionine, vitamin A deficiency, etc.) （2） Inhibition of melanocytosis (1) melanocyte inhibitory factor [MIF] secreted by hypothalamus and (2) melanocyte inhibitory factor [MCF] secreted by sympathetic nerve (3) Adrenocortical hormone secreted by adrenal gland can inhibit [MSH] (4) copper ion complexing agent, such as cysteine, glutathione, sodium thiosulfate, etc (5) Tyrosinase inhibition (6) Microelements: vitamins (vitamin E, C, a, zinc ion) (7) SOD, IL-6, TNF (8) Sunscreen (9) Redox agent (oxidation reaction inhibitor) (10) Angle peeling agent (11) Traditional Chinese medicine: Invigorating Qi and nourishing blood, promoting blood circulation and removing stasis (12) Black cell toxicity: such as: aminomercury, isopropylchitosanol, N-acetylcysteine, etc （1） Injection (1) vitamin C injection (2) Sodium thiosulfate powder for injection (3) Contains liquorice extract (Qianglining, Ganlixin, etc.) injection (4) Cysteine, glutathione injection (5) Traditional Chinese medicine, Danshen injection, etc （2） Oral agents (1) vitamin A, C, e, glycyrrhizin tablets, glycyrrhizin zinc (2) Corticosteroids, indomethacin (3) Traditional Chinese medicine, Yiqi Yangxue, Huoxue Huayu.