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Acute myocardial infarction (AMI) is one of the most common diseases in cardiology. Recent studies have shown the important role of an activated immune system and its products (interleukins) in the pathogenesis of AMI in these processes:
1. | Ischemia and reperfusion process with immune-mediated myocyte injury and postischemic myocardial inflammation (1 –3 ). |
2. | Structural and geometric changes in the left ventricle, commonly referred to as remodeling (4 ). |
3. | The process of myocyte apoptosis, leading to the loss of myocardial contractile function (5 ). |