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Nat Neurosci . . . Anesthetic analgesic mechanism: Central amygdala (CeA) anaesthetic neuron cluster.
Time of Update: 2020-07-21
on May 18, 2020, Professor Fan Wang of Duke University School of Medicine published the latest research results entitled "general anesthetics activate a potential central pain suppression circuit in the amygdala" online on Nature Neuroscience, GA) specifically activates a group of special neurons (ceaga) in the central amygdala (CEA), and this group of ceaga neurons plays an effective analgesic effect by inhibiting multiple downstream pain information processing brain regions.
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Brushyour phone before bed is prone to depression? The Xue Tian/Zhao Huan team reveals the neural mechanism of night-time blue light "depressing".
Time of Update: 2020-07-21
a research team led by Professor Xue Tian of China University of science and technology and Dr. Zhao Huan of Hefei University found that increasing blue light at night will affect specific neural circuits of the brain, and cause depression related symptoms.
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The Center for Brain Intelligence Excellence reveals DHA's mechanisms that promote neurodevelopment almost in the brain.
Time of Update: 2020-07-21
On May 19, cell reports online published a research paper entitled "in vivo mechanism of retinol like X receptor α regulating DHA dependent dendritic spine development and functional synaptic formation", which was completed by the research group of Yu Xiang, Center for excellence and innovation of brain science and intelligent technology, Chinese Academy of Sciences (Institute of Neuroscience) and State Key Laboratory of neuroscience.
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Rewrite the textbook! Today Science discovers a new pathway to "from the eye to the brain."
Time of Update: 2020-07-21
in fact, these cells can transmit light signals to more than 40 different brain regions, producing conscious visual perception, or performing some subconscious function (such as adjusting pupil size and biological rhythm).
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Nature Sub-journal: Playing with your phone before bed is prone to depression? Xue Tian team and other analysis of night blue light "depressing" neural mechanism.
Time of Update: 2020-07-21
this study describes for the first time the structure and function of the neural circuit that mediates the depression like phenotype induced by abnormal light at night, proves that it is abnormal light at night rather than rhythm or sleep disorder that causes depressive behavior, and finds that the excitability of the circuit is modulated by circadian rhythm gating, and explains the internal mechanism of the opposite emotional effect of light in day and night for the first time.
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The shock! When a person dreams, the brain is awake and can still obtain information selectively from the outside world.
Time of Update: 2020-07-21
scientists from CNRS, ens-psl and Monash University in Australia have shown that during the sleep phase associated with dreams, the brain suppresses information from the outside world, such as the voice of conversation.
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Tao Yuanxiang revealed a new mechanism for RNA methylation modification to participate in neuropathic pain.
Time of Update: 2020-07-21
peripheral nerve injury causes changes in the expression of pain related genes in the primary sensory neurons of the dorsal root ganglion (DRG) at the transcription and translation levels.
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Scientists have set up a new system of vascularized brain organ culture.
Time of Update: 2020-07-21
Wang Xiaoqun's research group, Institute of Biophysics, Chinese Academy of Sciences, has long been committed to the study of brain development and function.
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Science: Refresh awareness! Reveals non-classical pathways in which visual information is passed into the brain.
Time of Update: 2020-07-21
these functions are mainly realized by retinal ganglion cells (RGC), which are the only neurons in the retina that connect the brain and transmit retinal information from the eyes to the brain.
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Cell . . . Addiction treatment drugs with few side effects.
Time of Update: 2020-07-21
In this paper, we found that the β - arrestin2 biased ntsr1 ligand sbi-553 can also play a role in the treatment of addictive behavior, but there is no very small side effect.
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Nat Comm . . . Xu Yong's team reveals the secrets of sugar-sensitive neuronal perception to regulate blood sugar.
Time of Update: 2020-07-21
in this study, Xu Yong's team found a group of very sensitive glucose inhibitory and glucose excited neurons in the hypothalamus, and revealed the different ionic mechanisms of these glucose inhibited and glucose excited neurons to sense the changes of extracellular glucose concentration.
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Update: A new way to improve AD memory disorder? Scientists have discovered a new type of memory imprinted cell.
Time of Update: 2020-07-21
inhibition of memory imprinting cells in CA1 region impairs memory retrieval, and activation of these imprinted cells can perform memory retrieval even under amnesia or ad like symptoms (2).
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Experts interpret Neuron. Li Xiaoming's team reveals new mechanisms for cannabis analgesia.
Time of Update: 2020-07-21
on June 4, 2020, Professor Li Xiaoming Laboratory of Medical College of Zhejiang University published a research paper entitled "incerta thalamic circuit controls nocicensive behavior via cannabinoid type 1 receptors" in the journal Neuron, The GABAergic nerve circuit involved in pain response and revealed a new mechanism of pain relief by marijuana.
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Sleeping is also learning? For the first time, scientists have directly demonstrated that the brain "replays" learning content while sleeping.
Time of Update: 2020-07-21
the researchers say this is the first time there is direct evidence that the human brain replays waking experiences while sleeping.
in the past, memory scientists have observed through animal experiments that the neural firing patterns during waking can be "played back offline" during animal sleep.
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Cell: The evidence is conclusive! Memory trace cell groups are also subtyped.
Time of Update: 2020-07-21
these results can explain two problems: first, f-ram labeled neurons encode information of the same memory expressed in almost the same environment, which is a kind of memory generalization; while n-ram labeled neurons encode the information of the same memory which is different but similar to the environment, which is a process of memory differentiation.
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Activate this cluster of neurons and you may never feel pain again....
Time of Update: 2020-07-21
the researchers found that in addition to the supraoptic nucleus, general anesthesia drugs also activated a specific group of inhibitory neurons in the central amygdala, which they named ceaga neurons.
they found that ceaga neurons could send inhibitory signals to at least 16 brain regions involved in pain perception or related emotions.
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Cell sub-journal: Astral glial cells maintain a steady state of mitochondria and promote learning and memory.
Time of Update: 2020-07-21
in addition, under the condition of low and high glucose concentration, the glycolysis ability of GLP-1R knockout cells in vitro was enhanced and glucose intake was promoted.
Injection of FGF21 neutralizing antibody into the brain region could significantly reverse the enhancement of glucose metabolism induced by specific GLP-1R knockout.
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Pprotein and Cell . . . Wang Xiaoqun/Wu Wei collaborated on the Vivo-seq technique and revealed the molecular properties of the V1 epithelial photosensitive neurons in mice.
Time of Update: 2020-07-21
in recent years, Wang Xiaoqun, Institute of Biophysics, Chinese Academy of Sciences, has revealed the dynamic changes of cell types and transcriptional regulation mechanism in the development of prefrontal cortex and hippocampus (Zhong et al., nature, 2018; (nature | Wang Xiaoqun / Wu Qian cooperates to decode the cellular and molecular mechanisms of hippocampal development and formation, a key brain area for human learning and memory).
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Track language processing in non-reactive patients.
Time of Update: 2020-07-21
however, electroencephalogram (EEG) is more sensitive to brain activity, can better assess language processing, and distinguish between disturbance of consciousness (such as unresponsive arousal syndrome, UWS) and minimum state of consciousness (MCS).
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Upend tradition! PLOS Bio reveals that it's not staying up late that makes you fat, it's that obesity makes you sleepless.
Time of Update: 2020-07-21
the results showed that ATP levels in sleep deprived nematodes were significantly reduced, but they still stored too much fat, which was similar to human obesity.
