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European Radiology: The added value of radiomics features in predicting prognosis in patients with lung adenocarcinoma
Time of Update: 2022-11-25
In this study, SZM features were used to establish a risk model for overall survival, and compared it with traditional radiomics risk models and clinical variable-based risk models.
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About 30% of early-stage lung cancers will recur and metastasize after surgery! How to predict cancer recurrence, what experts say
Time of Update: 2022-11-25
Consensus 4: After radical resection in patients with early-stage NSCLC, a positive minimal residual disease (MRD) indicates a high risk of recurrence and requires closer follow-up management and consideration of more aggressive intervention strategies.
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Clin Cancer Res: Olaparib in metastatic castration-resistant prostate cancer with ctDNA BRCA/ATM variants
Time of Update: 2022-11-25
The Phase 3 PROfound study evaluated the efficacy of olaparib compared to abiraterone or enzalutamide (control) in patients with metastatic castration-resistant prostate cancer carrying HRR gene variants.
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Pay attention to the accurate screening of lung cancer in asymptomatic people, and early screening and early diagnosis of lung cancer
Time of Update: 2022-11-25
" On November 10, Liu Lunxu, executive vice president of West China Hospital of Sichuan University and vice chairman of the Thoracic and Cardiovascular Surgery Branch of the Chinese Medical Association, said in the first program of the series of live broadcasts "How to effectively detect early lung cancer".
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European Radiology: Application of prostate biopsy in the era of MRI-targeted therapy
Time of Update: 2022-11-25
MRI-targeted biopsy (TBx) increases the detection of clinically significant PCa (csPCa) while reducing the rate of false negatives compared to standard transrectal ultrasound (TRUS)-guided 12-core systematic biopsy (SBx).
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The latest paper by Taiwanese scholars: Chinese scholars are beginning to go global, and the global scientific center is shifting to the east
Time of Update: 2022-11-25
Recently, Zhang Zhiwei and others of the Center for Condensed Matter Science at National Taiwan University published an article in Science Reports arguing that the rapid rise of China's scientific level has gradually lost its aura to other scientific research powers that once stood on the top of the mountain (the United States, the United Kingdom, Germany, France, and Japan) - first the number of published papers, then the number of citations, and now highly cited papers.
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Nature Biotechnology: Engineered RNA polymerases to purify mRNA production and reduce immunostimulation byproducts
Time of Update: 2022-11-25
mRNA therapy is an emerging drug with some advantages over large molecule biologics and small molecule drugs. From a manufacturing perspective, a key advantage of mRNA therapeutics is the use of a sin
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European Radiology: How valuable is breast MR diffusion-weighted imaging?
Time of Update: 2022-11-25
5T and 3T scanners or only 3T scanners and their willingness to join the scanner working groupIn summary, the data presented in this study can better understand the role and value of DWI in breast clinical MRI, and provide a reference for its standardization and implementation.
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Nature Communications: Hippocampal astrocytes regulate anxious behavior
Time of Update: 2022-11-25
Figure 1: VR technology combined with two-photon microscopy to dynamically monitor astrocytes activityImmunofluorescence experiments showed that neuronal activity in the surrounding area after photoactivation of hippocampal astrocytes was also significantly increased, and electrophysiological experiments showed that activation of hippocampal astrocytes could enhance spontaneous postsynaptic current.
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Osimertinib resistance strategy is fully sorted out (recommended collection~)
Time of Update: 2022-11-25
Real case introduction: Professor Lu Shun of Shanghai Chest Hospital published a domestic case of trans mutation treatment in the journal JTO, a 42-year-old female lung adenocarcinoma 19Del patient was treated with osimertinib positive after multi-line drug resistance (erlotinib, chemotherapy).
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Eur Urol: Does a smaller age at the time of prostate-specific antigen detection reduce prostate cancer mortality?
Time of Update: 2022-11-25
screening for prostate PSA levels starting at age 50 to 55 years of age can significantly reduce the risk of PC death and is moreOriginal source:Original source:Sigrid V Carlsson, Rebecka Arnsrud Godtman, Carl-Gustav Pihl et al.
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European Radiology: AI-based computer-aided diagnosis in mammography
Time of Update: 2022-11-25
Recently, a study published in the journal European Radiology evaluated the abnormality score of breast cancer based on clinical, radiological and pathological features, and analyzed the breast cancer characteristics of false-negative cases in AI-CAD, providing a reference for the technology to better assist radiologists and clinicians.
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Japan's 5-year survival rate for stomach cancer has more than doubled! How to choose treatment for patients with different stages of gastric cancer
Time of Update: 2022-11-25
In July this year, a study published in JAMA (Journal of the American Medical Association) confirmed that the effect of laparoscopic surgery in patients with locally advanced gastric cancer is similar to that of open surgery, and the complication rate is significantly lower than that of open surgery.
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European Radiology: CT radiomics analysis improves preoperative prediction of lymph node metastasis in laryngeal squamous cell carcinoma
Time of Update: 2022-11-25
To our knowledge, few studies have explored the performance of CT radiology in predicting LNM for LSCCs. A study published in the journal European Radiology evaluated a CT-based radiomics model that will combine radiomics and independent clinical risk factors to enable preoperative predictive assessment of lymph node status in LSCC patients.
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Weekend Topic JAMA: Before what age does quitting smoking reduce the risk of death? 35!
Time of Update: 2022-11-25
Compared to participants who never smoked:Current smokers had a 180%, 238%, 134% and 1512% increased risk of death from all causes, cancer, cardiovascular disease and lower respiratory tract disease, respectively; In men, the associated risks were 170%, 240%, 127%, and 1306%, respectively; The associated risks in women were 190%, 229%, 144%, and 1595%, respectively.
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The "handle" of the anti-tumor community - moxibustion, used correctly, has many benefits
Time of Update: 2022-11-25
As one of the important external treatments of traditional medicine, moxibustion has the effects of supporting the solid foundation, warming the meridians, promoting qi and activating blood, dissipating stagnation and eliminating stasis, and has a significant effect in the treatment of tumors, especially in improving the symptoms of tumor patients, treating complications and reducing adverse reactions of radiotherapy and chemotherapy.
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Some key questions about mRNA vaccines
Time of Update: 2022-11-25
1 variants have glutamate (E) to lysine (K) mutations at position 484 (E484K) of the spike protein receptor binding domain, which promotes immune evasion 。 Fortunately, the FDA-approved mRNA vaccines BNT162b2 and mRNA-1273 produced cross-neutralizing antibodies against B.
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JAMA Oncol: Cost-effectiveness ratio for prostate cancer screening with MRI+ biopsy
Time of Update: 2022-11-25
Cost-effectiveness of Prostate Cancer Screening Using Magnetic Resonance Imaging or Standard Biopsy Based on the STHLM3-MRI Study.
Cost-effectiveness of Prostate Cancer Screening Using Magnetic Resonance Imaging or Standard Biopsy Based on the STHLM3-MRI Study.
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Take you to the Japanese proton therapy "guide" hospital and learn about the proton therapy process!
Time of Update: 2022-11-25
Non-invasive, painless, patients only need to lie on the bed, receive irradiation, can accurately "blast" tumor cells; Each treatment process does not exceed 30 minutes, after the end of the treatment
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Let's take a look at the magnificent history of the struggle between human beings and cancer, which is worth collecting
Time of Update: 2022-11-25
"Radiation therapy cured Hodgkin's disease SixPolitical action related to the war on cancerBuoyed by early chemotherapy victories, cancer prevention and control advocates, led by Lasker and Farber, urged the U.