Weekend Topic JAMA: Before what age does quitting smoking reduce the risk of death? 35！

The World Health Organization states that lifelong smoking reduces life expectancy by at least 10 years
.
However, with the increase in health awareness, many people have now started quitting activities
.
So, before what age do you quit smoking, and how long after quitting smoking, can lost life expectancy be restored?

In October 2022, a study published in JAMA Network Open in the Journal of the American Medical Association showed that for smokers, quitting smoking at any time can help reduce the risk of death; But the sooner you quit smoking, the lower the risk of death; Quitting smoking before age 35 is likely to return to a similar level of death to never-smokers
.

warn

smoke

↑ Paper link: https://jamanetwork.
com/journals/jamanetworkopen/fullarticle/2796614

01

1

Study samples

Researchers from the American Cancer Society (ACS), the University of Oxford in the United Kingdom, and the National University of Malaysia analyzed data from the National Health Visiting Survey (NHIS) from 1997 to 2018, including 551388 participants aged 25-84 years
.

The mean age of the participants was 48.
9 years, 243787 (44.
2%) were male and 307601 (55.
8%) were female
.

The researchers counted basic information such as height, weight, and ethnicity of the participants; Lifestyle information such as diet, alcohol consumption, physical activity, smoking status, age at initiation of smoking, age at quitting smoking, etc.
; and information
on the history and treatment of chronic diseases such as diabetes and hypertension.

The statistical results show:

A total of 74,870 participants died
during an average follow-up period of up to 11 years.
Among them, 38,078 (50.
9%) were women and 36,792 (49.
1%) were men; 19,433 (26%), 22,034 (29%) and 4,803 (6%) died
from cancer, cardiovascular disease and lower respiratory disease, respectively.

After removing other factors, the researchers found that smoking was associated with an increased risk of death; Smoking cessation significantly reduces the risk of
death.

Overall, approximately 44.
0% of all-cause deaths, 52.
2% of cancer deaths, 34.
7% of cardiovascular disease deaths and 86.
9% of lower respiratory disease deaths, as well as 31.
3% of male deaths and 22.
3% of female deaths, were related to
smoking.

2

Study results

Smoking is associated with an increased risk of death; Smoking cessation significantly reduces the risk of
death.

After removing other factors, the researchers found that, overall, about 44.
0 percent of all-cause deaths, 52.
2 percent of cancer deaths, 34.
7 percent of cardiovascular disease deaths and 86.
9 percent of lower respiratory disease deaths, as well as 31.
3 percent of male deaths and 22.
3 percent of female deaths, were related to
smoking.

Compared to participants who never smoked:

Current smokers had a 180%, 238%, 134% and 1512% increased risk of death from all causes, cancer, cardiovascular disease and lower respiratory tract disease, respectively; In men, the associated risks were 170%, 240%, 127%, and 1306%, respectively; The associated risks in women were 190%, 229%, 144%, and 1595%, respectively
.

People who had smoked had a 37%, 52%, 23% and 376% increased risk of death from all causes, cancer, cardiovascular disease and lower respiratory tract disease, respectively.
In men, the associated risk was 30%, 41%, 21%, and 287%, respectively; The associated risk in women was 46%, 61%, 30%, and 440%,
respectively.

The sooner you quit, the more you reduce your increased risk of death from smoking
.

Compared to participants who never smoked:

The longer you quit smoking, the more your increased risk of death decreases
.

Compared to participants who never smoked:

3

Conclusion of the study

The study concluded by noting that numerous studies have confirmed that smoking is associated with a higher risk of death; Quitting smoking is associated with
risk reversal.
The study's findings highlight that the earlier you quit, the more the risk of death from smoking reverses, even to levels similar to those of people who have never
smoked.

Researchers say that although smoking prevalence has declined in many countries around the world, smoking remains the leading preventable cause
of death worldwide.
More smoking cessation support should be provided to people who smoke to quit early; At the same time, raise health awareness and prevent non-smokers from starting to smoke
.

This will likely avert considerable smoking-related premature deaths and improve health and life expectancy
in the coming decades.

(This article is authorized to be reproduced from the WeChat public account "Health Press" 2022-11-01, originally "How old is quitting smoking before quitting smoking, how long after quitting smoking, can you return to normal life?") WuXi AppTec Content Team Editor; There are changes
when reprinting.
For reprinting authorization, please contact the original public number
.
）

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