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Zhejiang Pharmaceutical ARX305 obtains notification of acceptance of drug clinical trial application

 Last Update: 2021-12-24
 Source: Internet
 Author: User

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On December 22, Zhejiang Medicine issued an announcement stating that its subsidiary, Zhejiang Xinma Biomedicine Co.

Recombinant humanized anti-CD70 monoclonal antibody-AS269 conjugate (ARX305) for injection is a new generation of monoclonal antibody conjugate drug developed by the company on October 22, 2019, which signed the "Cooperative Development and License Agreement" with Ambrx in the United States.

As of November 30, 2021, the company's ARX305 project has invested a total of 65.

CD70 is a member of the tumor necrosis factor receptor (TNFR) superfamily.

The CD70 monoclonal antibodies that have been or are being developed abroad include MDX1411, ARGX-110 and SEA-CD70, and ADCs include SGN-75, SGN-CD70A, MDX-1203 and AMG172.

At present, there is no marketed drug targeting CD70 at home and abroad

Cancer is one of the most important public health problems in the 21st century, with high morbidity and mortality rates worldwide

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