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    Home > Medical News > Latest Medical News > Yangzijiang grabbed the first imitation of Shugeng Sodium Glucose, and Cinda’s revenue was 4.2 billion and a loss of 3.1 billion

    Yangzijiang grabbed the first imitation of Shugeng Sodium Glucose, and Cinda’s revenue was 4.2 billion and a loss of 3.1 billion

    • Last Update: 2022-04-16
    • Source: Internet
    • Author: User
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    share two news


    First, the official WeChat news of Yangzijiang Pharmaceuticals, the company's Shugeng Sodium Glucose Injection was approved and grabbed the first imitation
    .





    Sugammadex sodium is a specific binding neuromuscular blocking antagonist
    .




    The original research was developed by Merck & Co.


    of the United States.
    It was listed in Europe for the first time in July 2008 under the trade name Bridion.
    It was launched in Japan and the United States in 2010 and 2015



    Sugammadex sodium is a water-soluble modified γ-cyclodextrin drug that specifically binds to muscle relaxants through physical encapsulation to reverse the neuromuscular blockade effect
    .




    It is clinically used to reverse the state of muscle relaxation in patients with general anesthesia, and promote the recovery of spontaneous breathing and limb mobility
    .




    Merck's annual report shows that the annual sales of products in the global market in 2021 will be US$1.


    532 billion, a year-on-year increase of 27%.
    It is already a heavy product



    According to Yaohai data, the sales of the original research have grown rapidly since the launch, reaching nearly 300 million yuan last year
    .





    Such a heavyweight variety is of course a popular domestic imitation.


    Many large companies such as Kelun, Yangzijiang, Chia Tai Tianqing, and Hengrui have applied for listing, but 5 companies have failed to apply for listing



    declare enterprise Date Acceptance number
    Changsha Ruhong Pharmaceutical Technology Co.


    , Ltd.
    2022-03-07 CYHS2200397
    2022-03-07 CYHS2200396
    Hainan Ruizhi Pharmaceutical Technology Investment Co.
    , Ltd.
    2022-02-17 CYHS2200321
    Beijing Tide Pharmaceutical Co.
    , Ltd.



    Another news is that Innovent Bio announced its 2021 financial report
    .





    The financial report shows that Cinda's revenue in 2021 will be 4.


    269 billion yuan, 4 billion yuan will come from drug sales, and 269 million yuan will come from licensing fees



    The annual report does not disclose the specific sales of the flagship product, sintilimab.
    According to data estimates, the sales in 2021 will be about 3 billion yuan, and the cumulative sales of the product since its launch will be about 6.
    4 billion yuan
    .


    According to the International Financial Reporting Standards, the loss during the year was 3.
    138 billion yuan, an increase of more than 200% over the previous year
    .


    Sharing these two news, I want to say that it is really difficult to make medicine
    .


    It's hard to make generics
    .
    For companies that fail to apply for the listing of sugammadex sodium, the research and development expenses can only be wasted
    .
    Looking at the current application pattern, although Yangzijiang Pharmaceutical has grabbed the first imitation, it has too many chasing troops, and the pressure is not small.
    In the later stage, if multiple companies are approved and the products enter the centralized procurement, the price will not go up, and the profit will not be guaranteed
    .
    Enterprises that did not catch up with centralized procurement will have a more difficult life
    .


    It is more difficult to make innovative drugs
    .
    Innovent is regarded as a leader in innovative drug companies.
    It entered the industry early, has a strong team, has abundant pipelines, and has abundant funds.
    Even though 6 products have been launched, it still loses money
    .


    While maintaining high investment in research and development, Innovent is also investing heavily in market sales
    .
    In 2021, the investment in the market and sales expenses will be 2.
    541 billion yuan, accounting for 63.
    5% of product revenue
    .
    The sales force will increase from 1,284 in 2020 to 2,768 employees in 2021
    .


    I carefully studied the product pipeline of the next company.
    The listed products such as sintilimab, bevacizumab, rituximab, adalimumab, etc.
    , have fierce competition among domestic manufacturers with the same target and the same indication
    .



    According to the progress of the declaration, it will take time for the follow-up new products to be launched.
    That is to say, it is very difficult to increase sales and turn losses into profits only by relying on the varieties already on the market
    .


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