Xinjiang scientists have successfully extracted anticancer compounds from Camellia

In traditional minority medicine, how is the pharmacological effect of pricking sugar in the treatment of abdominal pain and diarrhea realized? In the study, the research team found that the extract of n-butanol from camel thorn had a significant inhibitory effect on intestinal propulsion in guinea pigs It was through anti acetylcholine to inhibit intestinal peristalsis so as to play a role in the treatment of abdominal pain and diarrhea Is there any other important use of camel thorn growing on the vast desert Gobi in Xinjiang besides its ecological security function? After four years of research, the scientists in our region found that some compounds isolated from Camellia have good performance in anti-oxidation, anti allergy, anti-tumor and other aspects, and their new compound anti-cancer activity was found for the first time This achievement passed the achievement appraisal organized by science and Technology Department of Xinjiang Uygur Autonomous Region at the beginning of this month Modern Chinese medicine and Chinese Journal of pharmacy have published their research results Camel thorn is a special deciduous shrub in arid desert area of our region The plant can secrete carbohydrate The thorn sugar collected after drying is a folk medicine used by ethnic minorities to treat abdominal pain, abdominal distention, diarrhea, tonic and strong, balance body fluid and abnormal bile fluid Since 2004, the Research Institute of traditional Chinese medicine and the research center of national medicine engineering and technology of the autonomous region have set up a research group of experts to conduct a comprehensive and systematic pharmacological activity screening of the extract parts of camel thorn, and at the same time, carry out six aspects of research, namely, anti-oxidation, anti allergy, anti-bacterial, anti-inflammatory and anti-tumor According to Jia Xiaoguang, director of the project design and the Institute of traditional Chinese medicine and ethnic medicine of the autonomous region, the research group has systematically studied the active chemical components of Camellia and acanthose through extraction, separation and purification, and has isolated and identified 50 compounds, 14 of which are found for the first time in camellia, 4 of which are found for the first time in Camellia, and the new compound isoflavone lignan The discovery of is a new compound This kind of substance is "hard to find in nature", showing medium intensity induction activity to mouse lung cancer cell line, "indicating that it has anti-cancer application value" It is found that the new compounds and isoflavones found in the plants of Camellia can be used as the leading compounds related to the efficacy of Camellia, providing scientific basis for the further development of antiallergic, antitumor, anti ulcer and antibacterial medicine So, in traditional minority medicine, how is the pharmacological effect of pricking sugar in the treatment of abdominal pain and diarrhea realized? In the study, the research team found that the extract of n-butanol from camel thorn had a significant inhibitory effect on intestinal propulsion in guinea pigs It was through anti acetylcholine to inhibit intestinal peristalsis so as to play a role in the treatment of abdominal pain and diarrhea It was found that the n-butanol extract of Camellia had no significant toxic and side effects on the survival of normal cells Experts believe that this provides a theoretical basis for the development of antiallergic agents This research is still blank in China and has obvious innovation Compared with the model group, the mucositis and superficial erosion were significantly improved According to the appraisal committee composed of seven experts, including Professor Gao Xiaoli from the school of pharmacy of Xinjiang Medical University, Geng Dongsheng, chief pharmacist of pharmacology of Xinjiang Drug Inspection Institute, and Ma Xiaokang, director of business department of Xinjiang Drug Inspection Institute, the project "explores the effective parts of the efficacy of camel thorn, with advanced methods, reliable data and innovative discoveries." According to the appraisal committee, "the project has great economic and social benefits, the level of science and technology is the first in China, the technology is mature, and the application value is great This basic research has played a demonstration role in the standardization and standardization of Uighur medicine." According to relevant evaluation, the research results have promoted the pharmaceutical research related to camel thorn and thorn sugar, "which has a positive role in promoting environmental protection, sand industry and sustainable development." Common sense: Camel thorn, known as a desert warrior, conquers nature with tenacious vitality It is also one of the "three treasures" of desert Gobi The other two treasures are Populus euphratica and red willow Camel grass, because it has a long body of hard thorns, people are more accustomed to call it camel thorn Camel thorn has the characteristics of cold resistance, drought resistance, salt resistance and wind sand resistance, and has the characteristics of strong adaptability, wide distribution and large area, especially in the North Xinjiang, Karamay, Changji and other places where there are a large number of wild camel thorn, which plays a very important role in preventing the land from being eroded by wind sand Camel thorn has the vitality of drought resistance, drought resistance, salt tolerance and alkalinity While protecting the wild camel thorn, we should research and use it.