Xinjiang grass flower effective parts five new drugs for Alzheimer's disease declaration

In September 5th, the the Xinjiang Uygur Autonomous Region science and Technology Department organized experts to accept the project "Research on the new effective drug for the treatment of Alzheimer's disease", which was undertaken by the Xinjiang Institute of physical and chemical technology, Chinese Academy of Sciences Grass flower is cotton flower The effective part of grass flower is the effective part of total flavonoids extracted and purified from cotton petals Xinjiang, as the main cotton producing area in China, has abundant raw materials of CaoHua However, although CaoHua, as a common Uyghur medicine, has been collected in the standard Uyghur medicine volume issued by the Ministry of health, its application scope is very small and its actual utilization is not high It is mainly discarded as a by-product of cotton production According to the relevant requirements of the "drug registration management regulations", the project carried out pre clinical pharmaceutical research on the effective parts of herbaceous flowers in the prevention of Alzheimer's disease, established the fingerprint, TLC identification and content determination of herbaceous flowers, completed the draft standard for herbal medicinal herbs, developed the molding technology of the total flavones of herbaceous flowers, and completed corresponding pilot production The quality standard of the crude drug and preparation and the preparation process of the control were established The accelerated stability experiment and long-term stability experiment of the total flavonoids tablet were completed, and the storage conditions and validity period of the total flavonoids tablet were determined The project has established a pilot production line for purification of total flavonoids of CaoHua by macroporous resin, obtained one national standard product certificate and two acceptance notices of five kinds of new drugs of traditional Chinese medicine, and achieved the breakthrough of zero acceptance of five kinds of new drugs in Xinjiang After listening to the report of the project leader, the expert group reviewed the relevant acceptance data, and believed that the CaoHua herbal medicine standard established by the project has been applied to the actual production of the pharmaceutical plant, and the isoquercetin standard products obtained have also been put on the market, which is of great significance to accelerate the modernization of national medicine and promote the regional economic development At the same time, through the comprehensive utilization of grass flowers, it can turn waste into treasure, effectively improve the additional output value of cotton, and is expected to contribute to increase the income of cotton farmers After discussion by the expert group, it was agreed that the project passed the acceptance.