Will taking antihypertensive drugs be resistant?

Is there anyone around you who knows that you have high blood pressure, but still eats meat and drinks heavily, and pays no attention to your eating habits? Knowing that I have high blood pressure, I am not willing to take medicine regularly, especially some young people

01Isthere resistance to antihypertensive drugs?

Many people worry that long-term consumption of a blood pressure medicine will lead to drug resistance

If there is no adverse reaction after a long period of time, it means that the patient can tolerate the drug well, and there is no need to worry about the side effects of using a drug for a long time, and there is no need to change the drug

On the contrary, frequent replacement of antihypertensive drugs may cause blood pressure fluctuations, which will adversely affect the heart, brain and kidney

If the blood pressure is only slightly to moderately elevated, there is no need to act too hastily.

There are certainly people who want to ask, but there are indeed some people who take a certain antihypertensive drug for a long time, and the effect of the drug gradually deteriorates.

02effect of antihypertensive drugs, "poor" is how is it?

There are many factors influencing blood pressure, and taking medicine is only one aspect

First of all, as many patients get older, their blood pressure will gradually increase (especially systolic blood pressure or "high pressure")

In this case, changing to another drug will generally not have a significant effect, so usually another drug is added to the original treatment plan

Secondly, in addition to the age factor, it may also be related to the patient's compliance

Finally, diet and life>

For such patients, the first thing to do is to strictly change their diet and living habits, because this is the basis for blood pressure control, and it is also a very important, safe, affordable and effective measure

In summary, some patients can control their blood pressure very well after taking a drug at the beginning, but after a few years, their blood pressure control becomes worse, but they mistakenly think that there is drug resistance, which is not the case

What if, as the age increases, the types of antihypertensive drugs taken by patients increase, but the blood pressure is still not well controlled? What should I do if I can't control blood pressure even after taking medicine?

03  diet and life>

According to the "Chinese Guidelines for the Prevention and Treatment of Hypertension in 2018", this type of hypertension is called refractory hypertension, that is, three kinds of antihypertensive drugs that can be tolerated and adequately applied on the basis of improving life>

Refractory hypertension may affect about 5% of the global population and 20%-30% of adult blood pressure; it will increase the risk of adverse cardiovascular events in patients with hypertension by 50% (including stroke, heart attack, and death) )

There are many factors influencing refractory hypertension

In the study, the researchers included a total of 140 patients with an average age of 63 years with refractory hypertension
.
Then they were divided into two groups.
90 participants received intensive, professionally supervised cardiac rehabilitation exercise training and diet counseling 3 times a week
.
The other 50 participants received health education and written instructions on exercise, weight loss, and nutritional goals, and were asked to go home to self-supervise
.

Four months later, the researchers found that compared with the self-supervised participants, the systolic blood pressure of the participants under professional supervision decreased by about 12mmHg on average
.
The blood pressure measurement results obtained by 24-hour dynamic monitoring showed that in the group under professional supervision, the systolic blood pressure of the subjects was reduced by an average of 7mmHg, while in the self-supervised group, there was no significant change in blood pressure
.
Participants supervised by professionals also had greater improvements in other key indicators of heart health, which indicates that these participants have a lower risk of future cardiovascular events
.

Reference

[1] Healthy changes in diet, activity improved treatment-resistant high blood pressure.
Retrieved SEPTEMBER 27, 2021, https://medicalxpress.
com/news/2021-09-healthy-diet-treatment-resistant-high-blood.
html

[2] James A.
Blumenthal et al.
, (2021).
Effects of Life>

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