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    Home > Biochemistry News > Natural Products News > Why is brown fat so important to the health of the body?

    Why is brown fat so important to the health of the body?

    • Last Update: 2020-07-28
    • Source: Internet
    • Author: User
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    ""This article has compiled a number of important research results to explain why brown fat is so important to the health of the body to share with everyone! Photo Credit: New Discovery! Brown fat may burn energy in an unexpected way! : When we are exposed to enough cold or exercise, small clusters of brown fat cells start to burn to produce energy From the Jocelyn Diabetes Research Center and other institutions scientists have found that this beneficial form of fat (brown fat) can be active in adultsIn a recent study published in the journal, researchers found an unexpected biological pathway in which brown fat cells convert energy into heat; studies in mice have shown that activating special pathways in brown or white fat precursor cells may help boost the heat-producing capacity of these cells without allowing them to accumulate fatPrevious researchers have found that specific biological signals that enhance brown fat cells appear to produce an unhelpful white fat cell, which could be one of the challenges the researchers have identified in this study, which may be possible to solve this challengeThe researchers who first studied proteins in mitochondria were key components that activate brown fat cellsNow researchers screened multiple mammalian proteins to identify key factors that increase yields in brown fat precursor cells: The mystery of many years has finally been solved! Revealing why brown adipose tissue is good for human health: Researchers at research institutions such as the University of California, San Francisco, have found in a new study how brown adipose tissue may help prevent obesity and diabetesTheir research increases our understanding of the role of brown adipose tissue in human health and may lead to the recent publication of new drug-related findings for the treatment of obesity and diabetesBrown adipose tissue is thought to be a heat generator tubePeople have several grams of the tissue in areas such as the neck, collarbone, kidneys and spinal cordWhen activated at low temperatures, brown adipose tissue uses sugar and fat in the blood to generate heat in the bodyThe study found that brown adipose tissue can also help the body filter and remove branched chain amino acids from the blood(leucine, isoleline and proline) are also found in supplements used by some athletes and people who want to increase muscle mass in foods such as eggs, meat, fish, chicken and milkThese amino acids are essential for good health at normal concentrations in the bloodThey are associated with diabetes and obesity when overdoses are presentThe researchers found that people with little or no brown adipose tissue were less able to clear the blood, which could lead to obesity and diabetes: Really? Can a cup of coffee stimulate the activity of brown fat to help the body lose weight effectively? Scientists from the University of Nottingham recently found that drinking a cup of coffee stimulates the body's brown fat () brown fat to resist fat and is a key finding to tackle obesity and diabetes in humans Published in the international journal The researchers have experimented with humans to find components that can have a direct impact on brown fat functionBrown fat tissue ( ) also becomes brown fat , an initial researcher who found brown fat in infant and hibernating mammals in infants and hibernating mammals People with lower BODY mass index (BMI) tend to have large amounts of brown fat in their bodies; the researchers say brown fat can function in a way that is different from other fats in the body, which often reacts to the cold by burning sugar and fat to generate heat for the body Increased activity improves blood sugar control and blood lipid levels, and extra calorie burning can also help with effective weight loss, but so far no scientist has been able to find an acceptable way to stimulate the activity of brown fat in humans Surprise: Accident! Brown adipose tissue is also involved in controlling food intake: scientists first discovered that the gut hormone trypslavin () stimulates the pancreas to secrete bicarbonate salts to aid the small intestine in the neutrality of acids and the digestion of the main nutrients In a new study, researchers from Germany and Finland found that the interaction of so-called "brown adipose tissue( )" in mice with pancreatic fluid can transmit nutritional signals about satiety to the brain during eating The study reinforces our understanding of the long-suspected role of brown adipose tissue in controlling food intake published in the journal The researchers say we show the association between the gut, brain and brown adipose tissue and reveal a previously unknown aspect of this complex regulatory system that controls energy balance The idea that brown fat is used only as a fever organ must be corrected and people need to pay more attention to its function in controlling hunger and satiety Signals encoded by intestinal hormones during eating reach the brain through the blood or through nerves activated in the small intestine In this new study, and colleagues found that the role of psoriasis in ego is not fully understood They found that hungry mice injected with pantry were inhibited in their appetite Injecting mice with pancreatic fluid also increases the amount of heat generated by their brown adipose tissue However, mice with inactivated brown adipose tissue did not experience the same appetite suppression when they received an amcredin injection, which suggested that it was the effects of pancreatitum on brown adipose tissue that led to satiety Scientists identify key molecules that give brown fat a special identity and are expected to develop new treatments for obesity and diabetes: Most fat cells in the human body are able to store energy, but everyone has a portion of brown fat doing the opposite job of burning calories to generate heat Now researchers from the Salk Institute have shed light on how special molecules give healthy brown fat energy to burn, allowing these cells to warm up when the body enters a cold state, published in the international journal, or could help scientists develop new targeted therapies for treatments for obesity-related diseases The researchers say this not only helps us understand how the body responds to the cold, but also helps us develop new ways to control the direct correlation between brown fat in the body and the occurrence of a variety of diseases, including obesity, diabetes and fatty liver disease Back in about a year ago, scientists believed that brown fat existed in the infant's body alone because babies could not produce heat by chilling, and since then researchers have found that adults who also contain brown fat in their bodies are more likely to contain high levels of brown fat despite very low levels and low body mass index (body mass index); Photo Source: Small molecules developed by Cassmedicine Drugs or activated browning to treat obesity: When excess energy accumulates in white adipose tissue causes obesity and brown adipose tissue can be decoupled by the heat-producing process to combat obesity White fat cells can also be transformed into brown-like cells (beige fat cells) with heat-producing functions under the influence of some external stimuli, such as freezing It is an important energy receptor that plays a role in regulating energy metabolism in a variety of tissues, but how the molecule participates in the function of adipose tissue, especially the browning process of white adipose tissue, is not fully understood To clarify the effects of fat cells on energy metabolism, researchers at the Shanghai Institute of Pharmaceutical Research of the University of Chinese Science, who constructed mice with fat cell-specific knockout of alpha, found that the mice were not tolerated in freezing and that mitochondrial integrity and mitochondrial production defects in subcutaneous white adipose tissue were inhibited in the expression of heat-producing genes in freezing environments Knockout mice fed a high-fat diet experienced increased obesity, increased liver fat immersion and fibrosis, and impaired glucose tolerance and insulin sensitivity At the same time, knockout mice experienced significant decreases in energy consumption and oxygen consumption under normal conditions and in the event of stimulation by beta-adrenaline receptor agonists Heavy weight! Scientists have successfully converted white fat into brown fat New obesity therapy is expected to be developed: in a recent study published in the international journal, researchers from the Caroline Institute and others explained the molecular mechanisms by studying mice that convert energy-stored white fat into energy-consuming brown fat Obesity is a major health problem facing the global population, and obesity at the same time increases the risk of a variety of diseases in the world, including cardiovascular disease, diabetes and cancer; Now scientists can effectively distinguish between white and brown fat, which make up most of the body's adipose tissue, which stores excess energy in the body, while brown fat produces heat for the body by consuming energy One possible treatment for obesity, the researchers point out, is to stimulate some white fat into brown fat New research reveals that natural weight-loss drugs in the body can activate brown fat-burning lipids: A small amount of brown fat scattered throughout the body after being activated by cold can burn calories to warm up and help reduce insulin resistance and alleviate other symptoms of diabetes and obesity Since the discovery that brown fat activates adults, researchers around the world have been studying how to activate it Now scientists from the Gasling Diabetes Center have discovered a way to turn the switch on "A lipid circulating in the blood can send signals to brown fat cells to burn other lipids in mice Dr Gaslin, a postdoctoral fellow and the first author of the article published in the paper, said In one experiment, low doses of obese mice had lower levels of triglycerides in their blood, while triglycerides were lipid molecules that increased the risk of heart disease and diabetes Although Gaslin's team has not shown that it promotes the activation of brown fat in the body, the lipid can act as a biomarker for the process to help people study the process Researchers in the field can now detect the activation of brown fat only by injecting small doses of radioactively labeled glucose and using positron radiation tomography imaging Series Review: Brown adipose tissue not only burns calories but also secretes organs: Brown adipose tissue is not only the body's main heat-producing organ but also the endocrine organ that secretes signal factors that activate fat and carbohydrate metabolism This is the main conclusion of an article published in Brown adipose tissue helps burn calories so that the body burns fat to produce heat According to the latest research, this special aditotissue tissue has endocrine function that activates the body's lipid and sugar metabolism, which is expected to become a therapeutic target for diseases such as obesity The researchers say that in the past brown adipose tissue was used only as a calorie-burning organ, but we saw that it also had endocrine effects New understanding of the function of brown adipose tissue is similar to the change in understanding of the function of white adipose tissue several years ago It was previously thought that white adipose tissue could only be used to store fat and later found that white adipose tissue was able to secrete leptin and then discovered other fat factors So brown adipose tissue is now being treated as an endocrine organ brown adipose and is now going through this process : Human cell line model research to help develop brown fat weight loss therapy: In a recent study published in the international journal, researchers from Harvard Medical School and others have successfully developed human brown fat and white fat precursor cell lines, which may help researchers more elaborately study specific factors that drive the development and activity of different types of cells The researchers say that by this way we can acquire human brown fat precursor cells and allow them to grow and grow them in a petri dish to become energy-consuming cells, the cellular system could serve as an important tool to help parse the biological properties of human brown fat tissue, of course, is also crucial to the development of new drug screening systems The development of new cell lines will encourage scientists to study gene expression in brown fat and white fat precursor cells or will help understand the mechanisms of brown fat cell formation and the molecular mechanisms that are regulated in the body, as well as to develop new technologies that promote how white fat cells are converted into brown fat cells () More wonderful counts! Stay tuned!
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