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▎Editor of WuXi AppTec's content team Sometimes, cancer patients have undergone very successful treatment, and the remaining cancer cells cannot be detected in the body, but after many years, the cancer will still recur, and the same type of cancer cells will be detected in the body.
Why is this? Researchers believe that part of the reason may be because some cancer cells have entered a state similar to "hibernation" and call this state "hibernation.
"
Image source: 123RF When cancer cells are in a dormant state, it means that they no longer divide and are difficult to detect.
Although cancer cells are known for their ability to grow, proliferate, and divide rapidly.
If cancer cells leave the tumor and continue to divide in a certain part of the body, even if they divide very slowly and are difficult to detect at the time, they will grow into tumors within a few years after treatment.
But when a cancer survivor’s cancer recurs 5-10 years after treatment, one of the most likely explanations is that these cancer cells are dormant and dormant for several years without dividing before they "wake up" and begin.
Rapid growth, proliferation and division.
At present, most cancer treatment methods are aimed at dividing cells, so dormant cancer cells can be prevented from being killed.
For these elusive cancer cells, researchers hope to learn more about them, including how they dormant and how to kill them.
Image source: How do 123RF cancer cells dormant? Researchers believe that there are several explanations for why cancer cells stop dividing and enter a dormant state.
The first explanation is that due to years of evolution, normal cells have a built-in inspection function that can count and control the number of times they proliferate.
This safety mechanism is often destroyed in cancer cells, but if this mechanism still exists in a cancer cell, the mechanism will trigger a cancer cell to enter a dormant state.
The second explanation is that cancer cells can also differentiate into more specialized cells, such as breast or intestinal cells, and stay in this state (this process is called terminal differentiation), and the cancer cells can no longer divide.
The third explanation is that cancer cells may also stop dividing due to some unknown principle.
It may be that cancer cells did not receive specific signals from surrounding cells or the environment, which affected their ability to divide.
It should be noted that no matter what causes one or some cancer cells to be in a dormant state, these cancer cells do not always remain in this dormant state.
Cancer cells can sometimes stay quietly somewhere in the body for years without dividing, and then for some reason, they can divide again, causing the cancer to recur.
Image source: 123RF study dormant cancer cells.
For cancer cells, researchers mainly study how they grow and divide.
For dormant cancer cells, the biggest difficulty for researchers is "If cells don’t divide, how do you study them?" Regarding dormant cancer cells, some key questions have not been answered—still don’t know what caused them.
Cancer cells are dormant, and what causes this behavior can be reversed.
Researchers also don't know where dormant cancer cells may be hiding in the body.
Because these cancer cells leave the original tumor and do not divide, it is difficult to find them.
Researchers have two main points about where dormant cancer cells may hide.
One is that dormant cancer cells may hide in body parts that the immune system cannot attack, such as bone marrow.
Then, when some reason triggers them to start dividing again, they may move to another organ and begin to develop into tumors.
Another view is that dormant cancer cells may be hidden in organs that eventually become tumors until they wake up for some reason and divide again.
Although studies have shown that both of the above conditions may occur, it is still uncertain which tumors these conditions occur in and what causes these different behaviors.
For researchers, it is very important to develop better tools to study dormant cancer cells.
Only in this way can it be possible to better understand dormant cancer cells and achieve the ultimate goal of killing dormant cancer cells.
.
Image source: 123RF solves the dormancy problem of cancer cells.
In order to target dormant cancer cells, researchers are studying several different treatment options.
The first is to kill dormant cancer cells by targeting substances specific to their surface.
Another option is to wake dormant cancer cells.
Scientists have been trying to force dormant cancer cells to divide again so that they will respond to traditional drugs such as chemotherapy.
However, there is still a long way to go before the second method is tried in cancer patients.
Because awakening dormant cancer cells is very dangerous, if the drugs used after awakening them are ineffective, or if all the cancer cells are not eliminated, it is tantamount to artificially speeding up cancer recurrence.
In other words, once dormant cancer cells are awakened and begin to divide, it must be ensured that the treatment strategy works and can kill all cancer cells.
For researchers, no matter what they do, it is necessary to understand the cause of cancer cell dormancy and the mechanism of awakening.
Some early-stage cancer patients seem to be cured after treatment, but the cancer eventually recurs.
For these patients, solving the problem of cancer cell dormancy may bring more beneficial effects.
Picture source: 123RF Conclusion In conclusion, if people can understand the way cancer cells enter dormancy and how to deal with dormant cancer cells, then the prognosis of some cancer patients is likely to be significantly improved.
We look forward to the success of researchers and one step further on the road to defeating cancer! It is recommended to read the data of nearly 200,000 people: Eat more of this kind of fish, and the risk of cardiovascular disease recurrence and death will be reduced by more than 15%.
Watch out for these 7 viruses in your life.
They are closely related to a variety of cancers! In addition to taking medicine, these 10 ways are also conducive to lowering blood pressure! Certain oncogene mutations existed more than 40 years before diagnosis! Harvard research brings new findings.
Oxford University research data of more than 400,000 people: people who love meat are more susceptible to heart disease, stroke, pneumonia, diabetes.
.
.
References [1] Science Surgery:'How do cancer cells remain dormant for many years?'.
Retrieved Mar 11 ,2021, from https://scienceblog.
cancerresearchuk.
org/2019/10/31/science-surgery-how-do-cancer-cells-remain-dormant-for-many-years/[ 2] What Is Cancer Recurrence?.
Retrieved Mar 11 ,2021, from https:// Note: This article aims to introduce the progress of medical and health research, not to recommend treatment options.
If you need guidance on treatment plans, please go to a regular hospital for treatment.
Why is this? Researchers believe that part of the reason may be because some cancer cells have entered a state similar to "hibernation" and call this state "hibernation.
"
Image source: 123RF When cancer cells are in a dormant state, it means that they no longer divide and are difficult to detect.
Although cancer cells are known for their ability to grow, proliferate, and divide rapidly.
If cancer cells leave the tumor and continue to divide in a certain part of the body, even if they divide very slowly and are difficult to detect at the time, they will grow into tumors within a few years after treatment.
But when a cancer survivor’s cancer recurs 5-10 years after treatment, one of the most likely explanations is that these cancer cells are dormant and dormant for several years without dividing before they "wake up" and begin.
Rapid growth, proliferation and division.
At present, most cancer treatment methods are aimed at dividing cells, so dormant cancer cells can be prevented from being killed.
For these elusive cancer cells, researchers hope to learn more about them, including how they dormant and how to kill them.
Image source: How do 123RF cancer cells dormant? Researchers believe that there are several explanations for why cancer cells stop dividing and enter a dormant state.
The first explanation is that due to years of evolution, normal cells have a built-in inspection function that can count and control the number of times they proliferate.
This safety mechanism is often destroyed in cancer cells, but if this mechanism still exists in a cancer cell, the mechanism will trigger a cancer cell to enter a dormant state.
The second explanation is that cancer cells can also differentiate into more specialized cells, such as breast or intestinal cells, and stay in this state (this process is called terminal differentiation), and the cancer cells can no longer divide.
The third explanation is that cancer cells may also stop dividing due to some unknown principle.
It may be that cancer cells did not receive specific signals from surrounding cells or the environment, which affected their ability to divide.
It should be noted that no matter what causes one or some cancer cells to be in a dormant state, these cancer cells do not always remain in this dormant state.
Cancer cells can sometimes stay quietly somewhere in the body for years without dividing, and then for some reason, they can divide again, causing the cancer to recur.
Image source: 123RF study dormant cancer cells.
For cancer cells, researchers mainly study how they grow and divide.
For dormant cancer cells, the biggest difficulty for researchers is "If cells don’t divide, how do you study them?" Regarding dormant cancer cells, some key questions have not been answered—still don’t know what caused them.
Cancer cells are dormant, and what causes this behavior can be reversed.
Researchers also don't know where dormant cancer cells may be hiding in the body.
Because these cancer cells leave the original tumor and do not divide, it is difficult to find them.
Researchers have two main points about where dormant cancer cells may hide.
One is that dormant cancer cells may hide in body parts that the immune system cannot attack, such as bone marrow.
Then, when some reason triggers them to start dividing again, they may move to another organ and begin to develop into tumors.
Another view is that dormant cancer cells may be hidden in organs that eventually become tumors until they wake up for some reason and divide again.
Although studies have shown that both of the above conditions may occur, it is still uncertain which tumors these conditions occur in and what causes these different behaviors.
For researchers, it is very important to develop better tools to study dormant cancer cells.
Only in this way can it be possible to better understand dormant cancer cells and achieve the ultimate goal of killing dormant cancer cells.
.
Image source: 123RF solves the dormancy problem of cancer cells.
In order to target dormant cancer cells, researchers are studying several different treatment options.
The first is to kill dormant cancer cells by targeting substances specific to their surface.
Another option is to wake dormant cancer cells.
Scientists have been trying to force dormant cancer cells to divide again so that they will respond to traditional drugs such as chemotherapy.
However, there is still a long way to go before the second method is tried in cancer patients.
Because awakening dormant cancer cells is very dangerous, if the drugs used after awakening them are ineffective, or if all the cancer cells are not eliminated, it is tantamount to artificially speeding up cancer recurrence.
In other words, once dormant cancer cells are awakened and begin to divide, it must be ensured that the treatment strategy works and can kill all cancer cells.
For researchers, no matter what they do, it is necessary to understand the cause of cancer cell dormancy and the mechanism of awakening.
Some early-stage cancer patients seem to be cured after treatment, but the cancer eventually recurs.
For these patients, solving the problem of cancer cell dormancy may bring more beneficial effects.
Picture source: 123RF Conclusion In conclusion, if people can understand the way cancer cells enter dormancy and how to deal with dormant cancer cells, then the prognosis of some cancer patients is likely to be significantly improved.
We look forward to the success of researchers and one step further on the road to defeating cancer! It is recommended to read the data of nearly 200,000 people: Eat more of this kind of fish, and the risk of cardiovascular disease recurrence and death will be reduced by more than 15%.
Watch out for these 7 viruses in your life.
They are closely related to a variety of cancers! In addition to taking medicine, these 10 ways are also conducive to lowering blood pressure! Certain oncogene mutations existed more than 40 years before diagnosis! Harvard research brings new findings.
Oxford University research data of more than 400,000 people: people who love meat are more susceptible to heart disease, stroke, pneumonia, diabetes.
.
.
References [1] Science Surgery:'How do cancer cells remain dormant for many years?'.
Retrieved Mar 11 ,2021, from https://scienceblog.
cancerresearchuk.
org/2019/10/31/science-surgery-how-do-cancer-cells-remain-dormant-for-many-years/[ 2] What Is Cancer Recurrence?.
Retrieved Mar 11 ,2021, from https:// Note: This article aims to introduce the progress of medical and health research, not to recommend treatment options.
If you need guidance on treatment plans, please go to a regular hospital for treatment.
